Autoimmune uveitis: study of treatment therapies

Detalhes bibliográficos
Autor(a) principal: Commodaro,Alessandra Gonçalves
Data de Publicação: 2010
Outros Autores: Moraes,Luciana de Deus Vieira de, Tambourgi,Denise Vilarinho, Belfort Jr.,Rubens, Sant’Anna,Osvaldo Augusto, Rizzo,Luiz Vicente
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Einstein (São Paulo)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082010000100117
Resumo: ABSTRACT Experimental autoimmune uveitis is an organ-specific T-cell mediated autoimmune disease characterized by inflammation and consequent destruction of the neural retina and adjacent tissues. Inflammation in experimental autoimmune uveitis may be induced in rodents by immunization with retinal antigens, such as interphotoreceptor retinoid-binding protein. We present a review of experimental studies that correlate primary immunobiological functions with this chronic disease and the possible use of molecules for the treatment of autoimmune uveitis.
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spelling Autoimmune uveitis: study of treatment therapiesUveitis/immunologyDisease models, animalAntigens/immunologyABSTRACT Experimental autoimmune uveitis is an organ-specific T-cell mediated autoimmune disease characterized by inflammation and consequent destruction of the neural retina and adjacent tissues. Inflammation in experimental autoimmune uveitis may be induced in rodents by immunization with retinal antigens, such as interphotoreceptor retinoid-binding protein. We present a review of experimental studies that correlate primary immunobiological functions with this chronic disease and the possible use of molecules for the treatment of autoimmune uveitis.Instituto Israelita de Ensino e Pesquisa Albert Einstein2010-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082010000100117einstein (São Paulo) v.8 n.1 2010reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.1590/s1679-45082010rb1416info:eu-repo/semantics/openAccessCommodaro,Alessandra GonçalvesMoraes,Luciana de Deus Vieira deTambourgi,Denise VilarinhoBelfort Jr.,RubensSant’Anna,Osvaldo AugustoRizzo,Luiz Vicenteeng2017-03-14T00:00:00Zoai:scielo:S1679-45082010000100117Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2017-03-14T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false
dc.title.none.fl_str_mv Autoimmune uveitis: study of treatment therapies
title Autoimmune uveitis: study of treatment therapies
spellingShingle Autoimmune uveitis: study of treatment therapies
Commodaro,Alessandra Gonçalves
Uveitis/immunology
Disease models, animal
Antigens/immunology
title_short Autoimmune uveitis: study of treatment therapies
title_full Autoimmune uveitis: study of treatment therapies
title_fullStr Autoimmune uveitis: study of treatment therapies
title_full_unstemmed Autoimmune uveitis: study of treatment therapies
title_sort Autoimmune uveitis: study of treatment therapies
author Commodaro,Alessandra Gonçalves
author_facet Commodaro,Alessandra Gonçalves
Moraes,Luciana de Deus Vieira de
Tambourgi,Denise Vilarinho
Belfort Jr.,Rubens
Sant’Anna,Osvaldo Augusto
Rizzo,Luiz Vicente
author_role author
author2 Moraes,Luciana de Deus Vieira de
Tambourgi,Denise Vilarinho
Belfort Jr.,Rubens
Sant’Anna,Osvaldo Augusto
Rizzo,Luiz Vicente
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Commodaro,Alessandra Gonçalves
Moraes,Luciana de Deus Vieira de
Tambourgi,Denise Vilarinho
Belfort Jr.,Rubens
Sant’Anna,Osvaldo Augusto
Rizzo,Luiz Vicente
dc.subject.por.fl_str_mv Uveitis/immunology
Disease models, animal
Antigens/immunology
topic Uveitis/immunology
Disease models, animal
Antigens/immunology
description ABSTRACT Experimental autoimmune uveitis is an organ-specific T-cell mediated autoimmune disease characterized by inflammation and consequent destruction of the neural retina and adjacent tissues. Inflammation in experimental autoimmune uveitis may be induced in rodents by immunization with retinal antigens, such as interphotoreceptor retinoid-binding protein. We present a review of experimental studies that correlate primary immunobiological functions with this chronic disease and the possible use of molecules for the treatment of autoimmune uveitis.
publishDate 2010
dc.date.none.fl_str_mv 2010-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082010000100117
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082010000100117
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/s1679-45082010rb1416
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
dc.source.none.fl_str_mv einstein (São Paulo) v.8 n.1 2010
reponame:Einstein (São Paulo)
instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron:IIEPAE
instname_str Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron_str IIEPAE
institution IIEPAE
reponame_str Einstein (São Paulo)
collection Einstein (São Paulo)
repository.name.fl_str_mv Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
repository.mail.fl_str_mv ||revista@einstein.br
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