Sulfone syndrome: A severe hypersensitivity reaction

Detalhes bibliográficos
Autor(a) principal: Marques, Gabriela Franco
Data de Publicação: 2012
Outros Autores: Barreto, Jaison Antônio, Sousa, Juliana Martins Prazeres, Brandão, Letícia Stella Gardini, Nigro, Maria Helena Mazzi Freire
Tipo de documento: Artigo
Idioma: por
Título da fonte: Hansenologia Internationalis (Online)
Texto Completo: https://periodicos.saude.sp.gov.br/hansenologia/article/view/36203
Resumo: Dapsone is a drug used to treat leprosy and other skin diseases. Even in normal doses can cause a condition called sulfona syndrome, characterized by fever, hepatitis exfoliative dermatitis, generalised lymphadenopathy, hemolytic anemia and atypical lymphocytes in peripheral blood. It’s a rare and severe hypersensitivity reaction to sulfone with an unpredictable clinical course. The authors report a case of sulfone syndrome, emphasizing its main clinical, laboratory and histopathological findings.
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spelling Sulfone syndrome: A severe hypersensitivity reactionSíndrome da Sulfona: uma grave reação de hipersensibilidadeHanseníaseDapsonaHipersensibilidade a DrogasLeprosyDapsoneDrug HypersensitivityDapsone is a drug used to treat leprosy and other skin diseases. Even in normal doses can cause a condition called sulfona syndrome, characterized by fever, hepatitis exfoliative dermatitis, generalised lymphadenopathy, hemolytic anemia and atypical lymphocytes in peripheral blood. It’s a rare and severe hypersensitivity reaction to sulfone with an unpredictable clinical course. The authors report a case of sulfone syndrome, emphasizing its main clinical, laboratory and histopathological findings.A dapsona é uma medicação utilizada no tratamento da hanseníase e outras doenças cutâneas. Mesmo em doses habituais pode causar um quadro denominado síndrome da sulfona caracterizado por febre, hepatite, dermatite esfoliativa, linfadenomegalia, anemia hemolítica e atipia linfocitária. Trata-se de uma rara e grave reação de hipersensibilidade à sulfona com curso clínico imprevisível. Os autores relatam um caso de síndrome da sulfona, enfatizando seus principais achados clínicos, laboratoriais e histopatológicos.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo2012-11-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3620310.47878/hi.2012.v37.36203Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 37 No. 2 (2012); 86-90Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 37 n. 2 (2012); 86-901982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLporhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/36203/34507https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMarques, Gabriela FrancoBarreto, Jaison AntônioSousa, Juliana Martins PrazeresBrandão, Letícia Stella GardiniNigro, Maria Helena Mazzi Freire2023-01-18T17:54:47Zoai:ojs.periodicos.saude.sp.gov.br:article/36203Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2023-01-18T17:54:47Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false
dc.title.none.fl_str_mv Sulfone syndrome: A severe hypersensitivity reaction
Síndrome da Sulfona: uma grave reação de hipersensibilidade
title Sulfone syndrome: A severe hypersensitivity reaction
spellingShingle Sulfone syndrome: A severe hypersensitivity reaction
Marques, Gabriela Franco
Hanseníase
Dapsona
Hipersensibilidade a Drogas
Leprosy
Dapsone
Drug Hypersensitivity
title_short Sulfone syndrome: A severe hypersensitivity reaction
title_full Sulfone syndrome: A severe hypersensitivity reaction
title_fullStr Sulfone syndrome: A severe hypersensitivity reaction
title_full_unstemmed Sulfone syndrome: A severe hypersensitivity reaction
title_sort Sulfone syndrome: A severe hypersensitivity reaction
author Marques, Gabriela Franco
author_facet Marques, Gabriela Franco
Barreto, Jaison Antônio
Sousa, Juliana Martins Prazeres
Brandão, Letícia Stella Gardini
Nigro, Maria Helena Mazzi Freire
author_role author
author2 Barreto, Jaison Antônio
Sousa, Juliana Martins Prazeres
Brandão, Letícia Stella Gardini
Nigro, Maria Helena Mazzi Freire
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Marques, Gabriela Franco
Barreto, Jaison Antônio
Sousa, Juliana Martins Prazeres
Brandão, Letícia Stella Gardini
Nigro, Maria Helena Mazzi Freire
dc.subject.por.fl_str_mv Hanseníase
Dapsona
Hipersensibilidade a Drogas
Leprosy
Dapsone
Drug Hypersensitivity
topic Hanseníase
Dapsona
Hipersensibilidade a Drogas
Leprosy
Dapsone
Drug Hypersensitivity
description Dapsone is a drug used to treat leprosy and other skin diseases. Even in normal doses can cause a condition called sulfona syndrome, characterized by fever, hepatitis exfoliative dermatitis, generalised lymphadenopathy, hemolytic anemia and atypical lymphocytes in peripheral blood. It’s a rare and severe hypersensitivity reaction to sulfone with an unpredictable clinical course. The authors report a case of sulfone syndrome, emphasizing its main clinical, laboratory and histopathological findings.
publishDate 2012
dc.date.none.fl_str_mv 2012-11-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/36203
10.47878/hi.2012.v37.36203
url https://periodicos.saude.sp.gov.br/hansenologia/article/view/36203
identifier_str_mv 10.47878/hi.2012.v37.36203
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/36203/34507
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
dc.source.none.fl_str_mv Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 37 No. 2 (2012); 86-90
Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 37 n. 2 (2012); 86-90
1982-5161
reponame:Hansenologia Internationalis (Online)
instname:Instituto Lauro de Souza Lima (ILSL)
instacron:ILSL
instname_str Instituto Lauro de Souza Lima (ILSL)
instacron_str ILSL
institution ILSL
reponame_str Hansenologia Internationalis (Online)
collection Hansenologia Internationalis (Online)
repository.name.fl_str_mv Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)
repository.mail.fl_str_mv hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br
_version_ 1796797580928090112

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