Diabetic status in leprosy
Autor(a) principal: | |
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Data de Publicação: | 1979 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Hansenologia Internationalis (Online) |
Texto Completo: | https://periodicos.saude.sp.gov.br/hansenologia/article/view/35626 |
Resumo: | The diabetic status of the local Jhansi patients (120 cases) was established before and after antileprosy treatment. Control studies were performed in normal healthy subjects (50 persons) without family history of diabetes mellitus. Random normals showed an incidence of diabetes only 2%, while leprosy patients (94 males and 26 females) had incidence of diabetic status of 14.2%. The highest incidence (19.3 %) of diabetes was in lepromatous leprosy and lowest incidence (6.4%) in tuberculoid leprosy patients. Repeated studies in leprosy after treatment showed not only clinical improvement for leprosy but also disappearance of the chemical and latent diabetes mellitus and lowering of blood sugar levels in manifest diabetes mellitus. Incidently it was noted that `diabetic status' was worse among males (82.3%) and with advancing age. Association and improvement of diabetic status with specific treatment would tentatively suggest that Mycobacterium leprae lesions are not confined to skin alone but somehow also related to carbohydrate metabolism. A careful management of the chemical and latent diabetes may help in clinical management of leprosy too. |
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Diabetic status in leprosyDiabetesHanseníaseDoença de HansenLepraDiabetesHanseniasisHansen's diseaseLeprosyThe diabetic status of the local Jhansi patients (120 cases) was established before and after antileprosy treatment. Control studies were performed in normal healthy subjects (50 persons) without family history of diabetes mellitus. Random normals showed an incidence of diabetes only 2%, while leprosy patients (94 males and 26 females) had incidence of diabetic status of 14.2%. The highest incidence (19.3 %) of diabetes was in lepromatous leprosy and lowest incidence (6.4%) in tuberculoid leprosy patients. Repeated studies in leprosy after treatment showed not only clinical improvement for leprosy but also disappearance of the chemical and latent diabetes mellitus and lowering of blood sugar levels in manifest diabetes mellitus. Incidently it was noted that `diabetic status' was worse among males (82.3%) and with advancing age. Association and improvement of diabetic status with specific treatment would tentatively suggest that Mycobacterium leprae lesions are not confined to skin alone but somehow also related to carbohydrate metabolism. A careful management of the chemical and latent diabetes may help in clinical management of leprosy too."O estado diabético" foi determinado em pacientes de hanseníase (120 casos) antes e depois do tratamento anti-hansênico. O grupo controle constitui-se de indivíduos normais, sadios (50 pessoas) sem história familiar de diabetes mellitus. O grupo controle mostrou uma incidência de diabetes de somente 2%, enquanto que nos pacientes de hanseníase (94 homens e 26 mulheres) a incidência do estado diabético foi de 14,2%. A maior incidência de diabetes (19,3%) foi verificada em pacientes virchowianos e a menor (6,4%) em doentes do tipo tuberculóide. Estudos repetidos após o tratamento mostraram não somente melhora clínica da hanseníase, como também o desaparecimento do diabetes mellitus químico e latente, com diminuição dos níveis sangüíneos de açúcar em casos de "diabetes mellitus" manifesto. Observou-se que o "estado diabético" é mais freqüentemente encontrado nos indivíduos de sexo masculino (82,3%) e em idade avançada. Esta associação e a melhoria do "estado diabético" com o tratamento específico poderiam sugerir que as lesões causadas pelo Mycobacterium leprae não estariam restritas à pele, mas também de alguma maneira, relacionadas ao metabolismo dos carbohidratos. O tratamento cuidadoso do diabetes químico e latente poderia também auxiliar o tratamento da hanse-níase.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo1979-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3562610.47878/hi.1979.v4.35626Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 4 No. 1 (1979); 7-14Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 4 n. 1 (1979); 7-141982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLporhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/35626/34030NIGAM, PraneshDAYAL, S. G.SRIVASTAVA, P.JOSHI, L . D.GOYAL, B. M.DUTT , BrahmaGUPTA, M. C.info:eu-repo/semantics/openAccess2021-05-19T20:56:21Zoai:ojs.periodicos.saude.sp.gov.br:article/35626Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2021-05-19T20:56:21Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false |
dc.title.none.fl_str_mv |
Diabetic status in leprosy |
title |
Diabetic status in leprosy |
spellingShingle |
Diabetic status in leprosy NIGAM, Pranesh Diabetes Hanseníase Doença de Hansen Lepra Diabetes Hanseniasis Hansen's disease Leprosy |
title_short |
Diabetic status in leprosy |
title_full |
Diabetic status in leprosy |
title_fullStr |
Diabetic status in leprosy |
title_full_unstemmed |
Diabetic status in leprosy |
title_sort |
Diabetic status in leprosy |
author |
NIGAM, Pranesh |
author_facet |
NIGAM, Pranesh DAYAL, S. G. SRIVASTAVA, P. JOSHI, L . D. GOYAL, B. M. DUTT , Brahma GUPTA, M. C. |
author_role |
author |
author2 |
DAYAL, S. G. SRIVASTAVA, P. JOSHI, L . D. GOYAL, B. M. DUTT , Brahma GUPTA, M. C. |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
NIGAM, Pranesh DAYAL, S. G. SRIVASTAVA, P. JOSHI, L . D. GOYAL, B. M. DUTT , Brahma GUPTA, M. C. |
dc.subject.por.fl_str_mv |
Diabetes Hanseníase Doença de Hansen Lepra Diabetes Hanseniasis Hansen's disease Leprosy |
topic |
Diabetes Hanseníase Doença de Hansen Lepra Diabetes Hanseniasis Hansen's disease Leprosy |
description |
The diabetic status of the local Jhansi patients (120 cases) was established before and after antileprosy treatment. Control studies were performed in normal healthy subjects (50 persons) without family history of diabetes mellitus. Random normals showed an incidence of diabetes only 2%, while leprosy patients (94 males and 26 females) had incidence of diabetic status of 14.2%. The highest incidence (19.3 %) of diabetes was in lepromatous leprosy and lowest incidence (6.4%) in tuberculoid leprosy patients. Repeated studies in leprosy after treatment showed not only clinical improvement for leprosy but also disappearance of the chemical and latent diabetes mellitus and lowering of blood sugar levels in manifest diabetes mellitus. Incidently it was noted that `diabetic status' was worse among males (82.3%) and with advancing age. Association and improvement of diabetic status with specific treatment would tentatively suggest that Mycobacterium leprae lesions are not confined to skin alone but somehow also related to carbohydrate metabolism. A careful management of the chemical and latent diabetes may help in clinical management of leprosy too. |
publishDate |
1979 |
dc.date.none.fl_str_mv |
1979-06-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/35626 10.47878/hi.1979.v4.35626 |
url |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/35626 |
identifier_str_mv |
10.47878/hi.1979.v4.35626 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/35626/34030 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
dc.source.none.fl_str_mv |
Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 4 No. 1 (1979); 7-14 Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 4 n. 1 (1979); 7-14 1982-5161 reponame:Hansenologia Internationalis (Online) instname:Instituto Lauro de Souza Lima (ILSL) instacron:ILSL |
instname_str |
Instituto Lauro de Souza Lima (ILSL) |
instacron_str |
ILSL |
institution |
ILSL |
reponame_str |
Hansenologia Internationalis (Online) |
collection |
Hansenologia Internationalis (Online) |
repository.name.fl_str_mv |
Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL) |
repository.mail.fl_str_mv |
hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br |
_version_ |
1796797580075597824 |