Diabetic status in leprosy

Detalhes bibliográficos
Autor(a) principal: NIGAM, Pranesh
Data de Publicação: 1979
Outros Autores: DAYAL, S. G., SRIVASTAVA, P., JOSHI, L . D., GOYAL, B. M., DUTT , Brahma, GUPTA, M. C.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Hansenologia Internationalis (Online)
Texto Completo: https://periodicos.saude.sp.gov.br/hansenologia/article/view/35626
Resumo: The diabetic status of the local Jhansi patients (120 cases) was established before and after antileprosy treatment. Control studies were performed in normal healthy subjects (50 persons) without family history of diabetes mellitus. Random normals showed an incidence of diabetes only 2%, while leprosy patients (94 males and 26 females) had incidence of diabetic status of 14.2%. The highest incidence (19.3 %) of diabetes was in lepromatous leprosy and lowest incidence (6.4%) in tuberculoid leprosy patients. Repeated studies in leprosy after treatment showed not only clinical improvement for leprosy but also disappearance of the chemical and latent diabetes mellitus and lowering of blood sugar levels in manifest diabetes mellitus. Incidently it was noted that `diabetic status' was worse among males (82.3%) and with advancing age. Association and improvement of diabetic status with specific treatment would tentatively suggest that Mycobacterium leprae lesions are not confined to skin alone but somehow also related to carbohydrate metabolism. A careful management of the chemical and latent diabetes may help in clinical management of leprosy too.
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spelling Diabetic status in leprosyDiabetesHanseníaseDoença de HansenLepraDiabetesHanseniasisHansen's diseaseLeprosyThe diabetic status of the local Jhansi patients (120 cases) was established before and after antileprosy treatment. Control studies were performed in normal healthy subjects (50 persons) without family history of diabetes mellitus. Random normals showed an incidence of diabetes only 2%, while leprosy patients (94 males and 26 females) had incidence of diabetic status of 14.2%. The highest incidence (19.3 %) of diabetes was in lepromatous leprosy and lowest incidence (6.4%) in tuberculoid leprosy patients. Repeated studies in leprosy after treatment showed not only clinical improvement for leprosy but also disappearance of the chemical and latent diabetes mellitus and lowering of blood sugar levels in manifest diabetes mellitus. Incidently it was noted that `diabetic status' was worse among males (82.3%) and with advancing age. Association and improvement of diabetic status with specific treatment would tentatively suggest that Mycobacterium leprae lesions are not confined to skin alone but somehow also related to carbohydrate metabolism. A careful management of the chemical and latent diabetes may help in clinical management of leprosy too."O estado diabético" foi determinado em pacientes de hanseníase (120 casos) antes e depois do tratamento anti-hansênico. O grupo controle constitui-se de indivíduos normais, sadios (50 pessoas) sem história familiar de diabetes mellitus. O grupo controle mostrou uma incidência de diabetes de somente 2%, enquanto que nos pacientes de hanseníase (94 homens e 26 mulheres) a incidência do estado diabético foi de 14,2%. A maior incidência de diabetes (19,3%) foi verificada em pacientes virchowianos e a menor (6,4%) em doentes do tipo tuberculóide. Estudos repetidos após o tratamento mostraram não somente melhora clínica da hanseníase, como também o desaparecimento do diabetes mellitus químico e latente, com diminuição dos níveis sangüíneos de açúcar em casos de "diabetes mellitus" manifesto. Observou-se que o "estado diabético" é mais freqüentemente encontrado nos indivíduos de sexo masculino (82,3%) e em idade avançada. Esta  associação e a melhoria do "estado diabético" com o tratamento específico poderiam sugerir que as lesões causadas pelo Mycobacterium leprae não estariam restritas à pele, mas também de alguma maneira, relacionadas ao metabolismo dos carbohidratos. O tratamento cuidadoso do diabetes químico e latente poderia também auxiliar o tratamento da hanse-níase.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo1979-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3562610.47878/hi.1979.v4.35626Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 4 No. 1 (1979); 7-14Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 4 n. 1 (1979); 7-141982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLporhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/35626/34030NIGAM, PraneshDAYAL, S. G.SRIVASTAVA, P.JOSHI, L . D.GOYAL, B. M.DUTT , BrahmaGUPTA, M. C.info:eu-repo/semantics/openAccess2021-05-19T20:56:21Zoai:ojs.periodicos.saude.sp.gov.br:article/35626Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2021-05-19T20:56:21Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false
dc.title.none.fl_str_mv Diabetic status in leprosy
title Diabetic status in leprosy
spellingShingle Diabetic status in leprosy
NIGAM, Pranesh
Diabetes
Hanseníase
Doença de Hansen
Lepra
Diabetes
Hanseniasis
Hansen's disease
Leprosy
title_short Diabetic status in leprosy
title_full Diabetic status in leprosy
title_fullStr Diabetic status in leprosy
title_full_unstemmed Diabetic status in leprosy
title_sort Diabetic status in leprosy
author NIGAM, Pranesh
author_facet NIGAM, Pranesh
DAYAL, S. G.
SRIVASTAVA, P.
JOSHI, L . D.
GOYAL, B. M.
DUTT , Brahma
GUPTA, M. C.
author_role author
author2 DAYAL, S. G.
SRIVASTAVA, P.
JOSHI, L . D.
GOYAL, B. M.
DUTT , Brahma
GUPTA, M. C.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv NIGAM, Pranesh
DAYAL, S. G.
SRIVASTAVA, P.
JOSHI, L . D.
GOYAL, B. M.
DUTT , Brahma
GUPTA, M. C.
dc.subject.por.fl_str_mv Diabetes
Hanseníase
Doença de Hansen
Lepra
Diabetes
Hanseniasis
Hansen's disease
Leprosy
topic Diabetes
Hanseníase
Doença de Hansen
Lepra
Diabetes
Hanseniasis
Hansen's disease
Leprosy
description The diabetic status of the local Jhansi patients (120 cases) was established before and after antileprosy treatment. Control studies were performed in normal healthy subjects (50 persons) without family history of diabetes mellitus. Random normals showed an incidence of diabetes only 2%, while leprosy patients (94 males and 26 females) had incidence of diabetic status of 14.2%. The highest incidence (19.3 %) of diabetes was in lepromatous leprosy and lowest incidence (6.4%) in tuberculoid leprosy patients. Repeated studies in leprosy after treatment showed not only clinical improvement for leprosy but also disappearance of the chemical and latent diabetes mellitus and lowering of blood sugar levels in manifest diabetes mellitus. Incidently it was noted that `diabetic status' was worse among males (82.3%) and with advancing age. Association and improvement of diabetic status with specific treatment would tentatively suggest that Mycobacterium leprae lesions are not confined to skin alone but somehow also related to carbohydrate metabolism. A careful management of the chemical and latent diabetes may help in clinical management of leprosy too.
publishDate 1979
dc.date.none.fl_str_mv 1979-06-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/35626
10.47878/hi.1979.v4.35626
url https://periodicos.saude.sp.gov.br/hansenologia/article/view/35626
identifier_str_mv 10.47878/hi.1979.v4.35626
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/35626/34030
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
dc.source.none.fl_str_mv Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 4 No. 1 (1979); 7-14
Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 4 n. 1 (1979); 7-14
1982-5161
reponame:Hansenologia Internationalis (Online)
instname:Instituto Lauro de Souza Lima (ILSL)
instacron:ILSL
instname_str Instituto Lauro de Souza Lima (ILSL)
instacron_str ILSL
institution ILSL
reponame_str Hansenologia Internationalis (Online)
collection Hansenologia Internationalis (Online)
repository.name.fl_str_mv Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)
repository.mail.fl_str_mv hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br
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