Type I reaction in lepromatous patients ten years after cure

Detalhes bibliográficos
Autor(a) principal: Ural, Somei
Data de Publicação: 2001
Outros Autores: Opromolla, Diltor Vladimir Araujo, Codoy, Deise Aparecida dos Santos, Fleury, Raul Negrão
Tipo de documento: Artigo
Idioma: por
Título da fonte: Hansenologia Internationalis (Online)
Texto Completo: https://periodicos.saude.sp.gov.br/hansenologia/article/view/36406
Resumo: A case of lepromatous leprosy patient treated with rifampin and dapsone for six months, and then treated with dapsone only for 14 years, is presented. The patient remained without lesions and with negative bacilloscopy for 10 years, and after this period he started again to show lesions, now with borderline aspect and appearance of bacilli. The authors suggest that the patient has always been a borderline whose disease has become more severe to the point that he presented a lepromatous aspect. When bacilli started to show up again, the patient's cellular immunity destroyed them so that borderline lesions appeared, as it must have happened in the initial phase of the disease. They also discuss the possible causes that led bacilli, probably persistent, to multiply again.
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spelling Type I reaction in lepromatous patients ten years after cureReação tipo I em paciente virchoviano dez anos após cura clínicahanseníase virchovianahanseníase dimorfareação tipo IimunoterapiaLepromatous leprosyborderline leprosytype I reactionimmunotherapyA case of lepromatous leprosy patient treated with rifampin and dapsone for six months, and then treated with dapsone only for 14 years, is presented. The patient remained without lesions and with negative bacilloscopy for 10 years, and after this period he started again to show lesions, now with borderline aspect and appearance of bacilli. The authors suggest that the patient has always been a borderline whose disease has become more severe to the point that he presented a lepromatous aspect. When bacilli started to show up again, the patient's cellular immunity destroyed them so that borderline lesions appeared, as it must have happened in the initial phase of the disease. They also discuss the possible causes that led bacilli, probably persistent, to multiply again.É apresentado o caso de um paciente virchoviano tratado com rifampicina e dapsona durante seis meses e depois somente com a dapsona durante 14 anos. Depois de permanecer sem lesões e com baciloscopia negativa por 10 anos, voltou a apresentar lesões, desta vez do tipo dimorfo e com reaparecimento de bacilos, Os autores sugerem que paciente sempre tenha sido um dimorfo e que havia piorado a ponto de apresentar aspectos virchovianos. Quando os bacilos voltaram a aparecer, a imunidade celular que o paciente sempre teve começou a destrui-los e daí o aparecimento de lesões dimorfas como deve ter sido no inicio de sua doença. Eles discutem também as causas possíveis que levaram os bacilos, possivelmente persistentes, a voltarem a se multiplicar.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo2001-11-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3640610.47878/hi.2001.v26.36406Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 26 No. 2 (2001); 117-120Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 26 n. 2 (2001); 117-1201982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLporhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/36406/34678https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessUral, SomeiOpromolla, Diltor Vladimir AraujoCodoy, Deise Aparecida dos SantosFleury, Raul Negrão2023-09-27T13:52:43Zoai:ojs.periodicos.saude.sp.gov.br:article/36406Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2023-09-27T13:52:43Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false
dc.title.none.fl_str_mv Type I reaction in lepromatous patients ten years after cure
Reação tipo I em paciente virchoviano dez anos após cura clínica
title Type I reaction in lepromatous patients ten years after cure
spellingShingle Type I reaction in lepromatous patients ten years after cure
Ural, Somei
hanseníase virchoviana
hanseníase dimorfa
reação tipo I
imunoterapia
Lepromatous leprosy
borderline leprosy
type I reaction
immunotherapy
title_short Type I reaction in lepromatous patients ten years after cure
title_full Type I reaction in lepromatous patients ten years after cure
title_fullStr Type I reaction in lepromatous patients ten years after cure
title_full_unstemmed Type I reaction in lepromatous patients ten years after cure
title_sort Type I reaction in lepromatous patients ten years after cure
author Ural, Somei
author_facet Ural, Somei
Opromolla, Diltor Vladimir Araujo
Codoy, Deise Aparecida dos Santos
Fleury, Raul Negrão
author_role author
author2 Opromolla, Diltor Vladimir Araujo
Codoy, Deise Aparecida dos Santos
Fleury, Raul Negrão
author2_role author
author
author
dc.contributor.author.fl_str_mv Ural, Somei
Opromolla, Diltor Vladimir Araujo
Codoy, Deise Aparecida dos Santos
Fleury, Raul Negrão
dc.subject.por.fl_str_mv hanseníase virchoviana
hanseníase dimorfa
reação tipo I
imunoterapia
Lepromatous leprosy
borderline leprosy
type I reaction
immunotherapy
topic hanseníase virchoviana
hanseníase dimorfa
reação tipo I
imunoterapia
Lepromatous leprosy
borderline leprosy
type I reaction
immunotherapy
description A case of lepromatous leprosy patient treated with rifampin and dapsone for six months, and then treated with dapsone only for 14 years, is presented. The patient remained without lesions and with negative bacilloscopy for 10 years, and after this period he started again to show lesions, now with borderline aspect and appearance of bacilli. The authors suggest that the patient has always been a borderline whose disease has become more severe to the point that he presented a lepromatous aspect. When bacilli started to show up again, the patient's cellular immunity destroyed them so that borderline lesions appeared, as it must have happened in the initial phase of the disease. They also discuss the possible causes that led bacilli, probably persistent, to multiply again.
publishDate 2001
dc.date.none.fl_str_mv 2001-11-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/36406
10.47878/hi.2001.v26.36406
url https://periodicos.saude.sp.gov.br/hansenologia/article/view/36406
identifier_str_mv 10.47878/hi.2001.v26.36406
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/36406/34678
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
dc.source.none.fl_str_mv Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 26 No. 2 (2001); 117-120
Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 26 n. 2 (2001); 117-120
1982-5161
reponame:Hansenologia Internationalis (Online)
instname:Instituto Lauro de Souza Lima (ILSL)
instacron:ILSL
instname_str Instituto Lauro de Souza Lima (ILSL)
instacron_str ILSL
institution ILSL
reponame_str Hansenologia Internationalis (Online)
collection Hansenologia Internationalis (Online)
repository.name.fl_str_mv Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)
repository.mail.fl_str_mv hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br
_version_ 1796797581375832064

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