Alternative treatment of multibacillary leprosy in a case of hepatotoxicity during multidrug therapy

Detalhes bibliográficos
Autor(a) principal: Marques, Gabriela Franco
Data de Publicação: 2012
Outros Autores: Barreto, Jaison Antônio, Sousa, Juliana Martins Prazeres, Brandão, Leticia Stella Gardini
Tipo de documento: Artigo
Idioma: por
Título da fonte: Hansenologia Internationalis (Online)
Texto Completo: https://periodicos.saude.sp.gov.br/hansenologia/article/view/36202
Resumo: The combination of dapsone, rifampicin and clofazimine has proven quite effective in the treatment of multibacillary leprosy, however dapsone is responsible for numerous side effects. We report a case of hepatoxocidade during multidrug therapy, successfully treated with the introduction of alternative treatment with rifampicin, clofazimine and ofloxacin.
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spelling Alternative treatment of multibacillary leprosy in a case of hepatotoxicity during multidrug therapyEsquema alternativo para tratamento de hanseníase multibacilar em um caso de hepatotoxicidade durante a poliquimioterapiaHanseníaseHanseníase MultibacilarQuimioterapia CombinadaLeprosyLeprosy, MultibacillaryDrug Therapy, CombinationThe combination of dapsone, rifampicin and clofazimine has proven quite effective in the treatment of multibacillary leprosy, however dapsone is responsible for numerous side effects. We report a case of hepatoxocidade during multidrug therapy, successfully treated with the introduction of alternative treatment with rifampicin, clofazimine and ofloxacin.A associação da dapsona, rifampicina e clofazimina tem se mostrado eficaz do tratamento da hanseníase multibacilar, entretanto a dapsona é responsável por inúmeros efeitos colaterais. Relata-se um caso de hepatoxocidade durante a poliquimioterapia, tratado com sucesso com a introdução de esquema alternativo com rifampicina, clofazimina e ofloxacino.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo2012-11-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3620210.47878/hi.2012.v37.36202Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 37 No. 2 (2012); 81-85Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 37 n. 2 (2012); 81-851982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLporhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/36202/34506https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMarques, Gabriela FrancoBarreto, Jaison AntônioSousa, Juliana Martins PrazeresBrandão, Leticia Stella Gardini2023-01-18T17:53:26Zoai:ojs.periodicos.saude.sp.gov.br:article/36202Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2023-01-18T17:53:26Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false
dc.title.none.fl_str_mv Alternative treatment of multibacillary leprosy in a case of hepatotoxicity during multidrug therapy
Esquema alternativo para tratamento de hanseníase multibacilar em um caso de hepatotoxicidade durante a poliquimioterapia
title Alternative treatment of multibacillary leprosy in a case of hepatotoxicity during multidrug therapy
spellingShingle Alternative treatment of multibacillary leprosy in a case of hepatotoxicity during multidrug therapy
Marques, Gabriela Franco
Hanseníase
Hanseníase Multibacilar
Quimioterapia Combinada
Leprosy
Leprosy, Multibacillary
Drug Therapy, Combination
title_short Alternative treatment of multibacillary leprosy in a case of hepatotoxicity during multidrug therapy
title_full Alternative treatment of multibacillary leprosy in a case of hepatotoxicity during multidrug therapy
title_fullStr Alternative treatment of multibacillary leprosy in a case of hepatotoxicity during multidrug therapy
title_full_unstemmed Alternative treatment of multibacillary leprosy in a case of hepatotoxicity during multidrug therapy
title_sort Alternative treatment of multibacillary leprosy in a case of hepatotoxicity during multidrug therapy
author Marques, Gabriela Franco
author_facet Marques, Gabriela Franco
Barreto, Jaison Antônio
Sousa, Juliana Martins Prazeres
Brandão, Leticia Stella Gardini
author_role author
author2 Barreto, Jaison Antônio
Sousa, Juliana Martins Prazeres
Brandão, Leticia Stella Gardini
author2_role author
author
author
dc.contributor.author.fl_str_mv Marques, Gabriela Franco
Barreto, Jaison Antônio
Sousa, Juliana Martins Prazeres
Brandão, Leticia Stella Gardini
dc.subject.por.fl_str_mv Hanseníase
Hanseníase Multibacilar
Quimioterapia Combinada
Leprosy
Leprosy, Multibacillary
Drug Therapy, Combination
topic Hanseníase
Hanseníase Multibacilar
Quimioterapia Combinada
Leprosy
Leprosy, Multibacillary
Drug Therapy, Combination
description The combination of dapsone, rifampicin and clofazimine has proven quite effective in the treatment of multibacillary leprosy, however dapsone is responsible for numerous side effects. We report a case of hepatoxocidade during multidrug therapy, successfully treated with the introduction of alternative treatment with rifampicin, clofazimine and ofloxacin.
publishDate 2012
dc.date.none.fl_str_mv 2012-11-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/36202
10.47878/hi.2012.v37.36202
url https://periodicos.saude.sp.gov.br/hansenologia/article/view/36202
identifier_str_mv 10.47878/hi.2012.v37.36202
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/36202/34506
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
dc.source.none.fl_str_mv Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 37 No. 2 (2012); 81-85
Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 37 n. 2 (2012); 81-85
1982-5161
reponame:Hansenologia Internationalis (Online)
instname:Instituto Lauro de Souza Lima (ILSL)
instacron:ILSL
instname_str Instituto Lauro de Souza Lima (ILSL)
instacron_str ILSL
institution ILSL
reponame_str Hansenologia Internationalis (Online)
collection Hansenologia Internationalis (Online)
repository.name.fl_str_mv Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)
repository.mail.fl_str_mv hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br
_version_ 1796797580924944384

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