Mast cells in histoid lepromatous lesions
Autor(a) principal: | |
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Data de Publicação: | 1985 |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Hansenologia Internationalis (Online) |
Texto Completo: | https://periodicos.saude.sp.gov.br/hansenologia/article/view/35553 |
Resumo: | Ten patients with histoid lesions among the lepromatous leprosy cases, of both sexes in the age group of 35-65 years, were included in this study. Skin biopsy from the nodule with surrounding healthy skin of histoid lesion was taken. The biopsies were fixed in Susa solution and processed for light microscopy. 5-7µ thick sections were cut and stained with haematoxylin and eosin, Toluidlne blue and Fite Faraco. Observations were made on the dermis to locate the mast cells and bacili. Proliferation of mast cells and their degranulation were seen in the histoid nodule as compared to surrounding normal healthy skin where the cells were mainly intact. The study further investigates the role of mast cells in the histopathogenesis of the disease. |
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Mast cells in histoid lepromatous lesionsHanseníase históideMastócitosHistoid leprosyHistoid hanseniasisMast cellsTen patients with histoid lesions among the lepromatous leprosy cases, of both sexes in the age group of 35-65 years, were included in this study. Skin biopsy from the nodule with surrounding healthy skin of histoid lesion was taken. The biopsies were fixed in Susa solution and processed for light microscopy. 5-7µ thick sections were cut and stained with haematoxylin and eosin, Toluidlne blue and Fite Faraco. Observations were made on the dermis to locate the mast cells and bacili. Proliferation of mast cells and their degranulation were seen in the histoid nodule as compared to surrounding normal healthy skin where the cells were mainly intact. The study further investigates the role of mast cells in the histopathogenesis of the disease.Foram incluídos neste estudo dez pacientes de hanseníase virchowiana, de ambos os sexos, na faixa etária de 35 a 65 anos, que apresentavam lesões históides. Foi realizada biopsia do nódulo cutâneo, incluindo pele sã ao redor. Após fixação, as biopsias foram processadas para microscopia óptica; cortes de 5 a 7 µ foram corados pela Hematoxilina eosina. Azul de Tolui-dina e Fite Faraco. Examinou-se a derma para localização de mastócitos e bacilos. A proliferação dos mastócitos e sua degranulação foram observadas no nódulo históide e comparadas com a pele normal circunjacente, onde as células se encontravam em sua maioria intactas. O trabalho investiga ainda o papel dos mastócitos na histopatogenia da doença.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo1985-11-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3555310.47878/hi.1985.v10.35553Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 10 No. 1/2 (1985); 1-4Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 10 n. 1/2 (1985); 1-41982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLenghttps://periodicos.saude.sp.gov.br/hansenologia/article/view/35553/33958KUMAR, Raniinfo:eu-repo/semantics/openAccess2021-11-23T16:31:40Zoai:ojs.periodicos.saude.sp.gov.br:article/35553Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2021-11-23T16:31:40Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false |
dc.title.none.fl_str_mv |
Mast cells in histoid lepromatous lesions |
title |
Mast cells in histoid lepromatous lesions |
spellingShingle |
Mast cells in histoid lepromatous lesions KUMAR, Rani Hanseníase históide Mastócitos Histoid leprosy Histoid hanseniasis Mast cells |
title_short |
Mast cells in histoid lepromatous lesions |
title_full |
Mast cells in histoid lepromatous lesions |
title_fullStr |
Mast cells in histoid lepromatous lesions |
title_full_unstemmed |
Mast cells in histoid lepromatous lesions |
title_sort |
Mast cells in histoid lepromatous lesions |
author |
KUMAR, Rani |
author_facet |
KUMAR, Rani |
author_role |
author |
dc.contributor.author.fl_str_mv |
KUMAR, Rani |
dc.subject.por.fl_str_mv |
Hanseníase históide Mastócitos Histoid leprosy Histoid hanseniasis Mast cells |
topic |
Hanseníase históide Mastócitos Histoid leprosy Histoid hanseniasis Mast cells |
description |
Ten patients with histoid lesions among the lepromatous leprosy cases, of both sexes in the age group of 35-65 years, were included in this study. Skin biopsy from the nodule with surrounding healthy skin of histoid lesion was taken. The biopsies were fixed in Susa solution and processed for light microscopy. 5-7µ thick sections were cut and stained with haematoxylin and eosin, Toluidlne blue and Fite Faraco. Observations were made on the dermis to locate the mast cells and bacili. Proliferation of mast cells and their degranulation were seen in the histoid nodule as compared to surrounding normal healthy skin where the cells were mainly intact. The study further investigates the role of mast cells in the histopathogenesis of the disease. |
publishDate |
1985 |
dc.date.none.fl_str_mv |
1985-11-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/35553 10.47878/hi.1985.v10.35553 |
url |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/35553 |
identifier_str_mv |
10.47878/hi.1985.v10.35553 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/35553/33958 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
dc.source.none.fl_str_mv |
Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 10 No. 1/2 (1985); 1-4 Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 10 n. 1/2 (1985); 1-4 1982-5161 reponame:Hansenologia Internationalis (Online) instname:Instituto Lauro de Souza Lima (ILSL) instacron:ILSL |
instname_str |
Instituto Lauro de Souza Lima (ILSL) |
instacron_str |
ILSL |
institution |
ILSL |
reponame_str |
Hansenologia Internationalis (Online) |
collection |
Hansenologia Internationalis (Online) |
repository.name.fl_str_mv |
Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL) |
repository.mail.fl_str_mv |
hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br |
_version_ |
1796797579753684992 |