Mast cells in histoid lepromatous lesions

Detalhes bibliográficos
Autor(a) principal: KUMAR, Rani
Data de Publicação: 1985
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Hansenologia Internationalis (Online)
Texto Completo: https://periodicos.saude.sp.gov.br/hansenologia/article/view/35553
Resumo: Ten patients with histoid lesions among the lepromatous leprosy cases, of both sexes in the age group of 35-65 years, were included in this study. Skin biopsy from the nodule with surrounding healthy skin of histoid lesion was taken. The biopsies were fixed in Susa solution and processed for light microscopy. 5-7µ thick sections were cut and stained with haematoxylin and eosin, Toluidlne blue and Fite Faraco. Observations were made on the dermis to locate the mast cells and bacili. Proliferation of mast cells and their degranulation were seen in the histoid nodule as compared to surrounding normal healthy skin where the cells were mainly intact. The study further investigates the role of mast cells in the histopathogenesis of the disease.
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spelling Mast cells in histoid lepromatous lesionsHanseníase históideMastócitosHistoid leprosyHistoid hanseniasisMast cellsTen patients with histoid lesions among the lepromatous leprosy cases, of both sexes in the age group of 35-65 years, were included in this study. Skin biopsy from the nodule with surrounding healthy skin of histoid lesion was taken. The biopsies were fixed in Susa solution and processed for light microscopy. 5-7µ thick sections were cut and stained with haematoxylin and eosin, Toluidlne blue and Fite Faraco. Observations were made on the dermis to locate the mast cells and bacili. Proliferation of mast cells and their degranulation were seen in the histoid nodule as compared to surrounding normal healthy skin where the cells were mainly intact. The study further investigates the role of mast cells in the histopathogenesis of the disease.Foram incluídos neste estudo dez pacientes de hanseníase virchowiana, de ambos os sexos, na faixa etária de 35 a 65 anos, que apresentavam lesões históides. Foi realizada biopsia do nódulo cutâneo, incluindo pele sã ao redor. Após fixação, as biopsias foram processadas para microscopia óptica; cortes de 5 a 7 µ foram corados pela Hematoxilina eosina. Azul de Tolui-dina e Fite Faraco. Examinou-se a derma para localização de mastócitos e bacilos. A proliferação dos mastócitos e sua degranulação foram observadas no nódulo históide e comparadas com a pele normal circunjacente, onde as células se encontravam em sua maioria intactas. O trabalho investiga ainda o papel dos mastócitos na histopatogenia da doença.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo1985-11-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3555310.47878/hi.1985.v10.35553Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 10 No. 1/2 (1985); 1-4Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 10 n. 1/2 (1985); 1-41982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLenghttps://periodicos.saude.sp.gov.br/hansenologia/article/view/35553/33958KUMAR, Raniinfo:eu-repo/semantics/openAccess2021-11-23T16:31:40Zoai:ojs.periodicos.saude.sp.gov.br:article/35553Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2021-11-23T16:31:40Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false
dc.title.none.fl_str_mv Mast cells in histoid lepromatous lesions
title Mast cells in histoid lepromatous lesions
spellingShingle Mast cells in histoid lepromatous lesions
KUMAR, Rani
Hanseníase históide
Mastócitos
Histoid leprosy
Histoid hanseniasis
Mast cells
title_short Mast cells in histoid lepromatous lesions
title_full Mast cells in histoid lepromatous lesions
title_fullStr Mast cells in histoid lepromatous lesions
title_full_unstemmed Mast cells in histoid lepromatous lesions
title_sort Mast cells in histoid lepromatous lesions
author KUMAR, Rani
author_facet KUMAR, Rani
author_role author
dc.contributor.author.fl_str_mv KUMAR, Rani
dc.subject.por.fl_str_mv Hanseníase históide
Mastócitos
Histoid leprosy
Histoid hanseniasis
Mast cells
topic Hanseníase históide
Mastócitos
Histoid leprosy
Histoid hanseniasis
Mast cells
description Ten patients with histoid lesions among the lepromatous leprosy cases, of both sexes in the age group of 35-65 years, were included in this study. Skin biopsy from the nodule with surrounding healthy skin of histoid lesion was taken. The biopsies were fixed in Susa solution and processed for light microscopy. 5-7µ thick sections were cut and stained with haematoxylin and eosin, Toluidlne blue and Fite Faraco. Observations were made on the dermis to locate the mast cells and bacili. Proliferation of mast cells and their degranulation were seen in the histoid nodule as compared to surrounding normal healthy skin where the cells were mainly intact. The study further investigates the role of mast cells in the histopathogenesis of the disease.
publishDate 1985
dc.date.none.fl_str_mv 1985-11-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/35553
10.47878/hi.1985.v10.35553
url https://periodicos.saude.sp.gov.br/hansenologia/article/view/35553
identifier_str_mv 10.47878/hi.1985.v10.35553
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/35553/33958
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
dc.source.none.fl_str_mv Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 10 No. 1/2 (1985); 1-4
Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 10 n. 1/2 (1985); 1-4
1982-5161
reponame:Hansenologia Internationalis (Online)
instname:Instituto Lauro de Souza Lima (ILSL)
instacron:ILSL
instname_str Instituto Lauro de Souza Lima (ILSL)
instacron_str ILSL
institution ILSL
reponame_str Hansenologia Internationalis (Online)
collection Hansenologia Internationalis (Online)
repository.name.fl_str_mv Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)
repository.mail.fl_str_mv hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br
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