La función hepática através del espectro clinico de la hanseniasis

Detalhes bibliográficos
Autor(a) principal: Pacin, Ana
Data de Publicação: 1980
Outros Autores: Fliess, Enrique L., Llorente, Berta E
Tipo de documento: Artigo
Idioma: spa
Título da fonte: Hansenologia Internationalis (Online)
Texto Completo: https://periodicos.saude.sp.gov.br/hansenologia/article/view/36103
Resumo: The liver function was studied in 100 hanseniasis patients. They were classified in the following 10 groups: quiescent LL (20 patients), quiescent BL (13 patients), quiescent BB (7 patients), quiescent BT (9 patients), quiescent TT (12 patients), reactional LL (12 patients), reactional BL (10 patients), reactional BB (7 patients) 4 reactional BT (5 patients), reactional TT (5 patients); a comparison was made with a control group (10 healthy individuals). It was found a hyperproteinemia with high levels of globulin and normal levels of albumin in the serum of all clinical forms, and a typical pattern of "light damage hepatic cells" with raised in the enzymatic activity of GOT, GPT and alkaline phosphatase with no changes in turbidity tests and bilirrubinemia, in all reactional patients. The physiopathology of this problem and the types III and IV hypersensitivity phenomena are discussed.
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spelling La función hepática através del espectro clinico de la hanseniasisHanseniasisEnzymatic activityLiver function testsHanseniasisActividad enzimáticaPruebas de función hepáticaThe liver function was studied in 100 hanseniasis patients. They were classified in the following 10 groups: quiescent LL (20 patients), quiescent BL (13 patients), quiescent BB (7 patients), quiescent BT (9 patients), quiescent TT (12 patients), reactional LL (12 patients), reactional BL (10 patients), reactional BB (7 patients) 4 reactional BT (5 patients), reactional TT (5 patients); a comparison was made with a control group (10 healthy individuals). It was found a hyperproteinemia with high levels of globulin and normal levels of albumin in the serum of all clinical forms, and a typical pattern of "light damage hepatic cells" with raised in the enzymatic activity of GOT, GPT and alkaline phosphatase with no changes in turbidity tests and bilirrubinemia, in all reactional patients. The physiopathology of this problem and the types III and IV hypersensitivity phenomena are discussed.Se estudie la función hepática en 100 pacientes hansenianos agrupados segtin la clasificación espectral y la presencia o no de episodios reaccionales del siguiente modo; pacientes quiescentes: 20 LL, 13 BL, 7 BB, 9 BT, 12 TT. Pacientes reaccionales: 12 LL, 10 BL, 7 BB, 5 BT, 5 TT. Como grupo testigo se estudiaron 10 individuos sanos no contactantes con pacientes hansenianos y sin antecedentes de patología hepática. Los resultados obtenidos muestran una hiperproteinemia a expensas de las globulinas sin disminución de albúmina en todas las formas clínicas de la hanseniasis, reaccionales y quiescentes, y un aumento de la actividad enzimática sérica de GPT, GOT y fosfatasa alcalina en los pacientes reacciónales. Estos incrementos de la actividad enzimática caracterizan un daño hepatocelular leve, en que la bilirruhinemia y la prueba de turbidez del timol no presentan alteraciones. Se discuten los mecanismos fisiopatológicos causantes de estas alteraciones, postulándose su vinculación con fenómenos de hipersensibilidad a tipo III y IV.The liver function was studied in 100 hanseniasis patients. They were classified in the following 10 groups: quiescent LL (20 patients), quiescent BL (13 patients), quiescent BB (7 patients), quiescent BT (9 patients), quiescent TT (12 patients), reactional LL (12 patients), reactional BL (10 patients), reactional BB (7 patients) 4 reactional BT (5 patients), reactional TT (5 patients); a comparison was made with a control group (10 healthy individuals). It was found a hyperproteinemia with high levels of globulin and normal levels of albumin in the serum of all clinical forms, and a typical pattern of "light damage hepatic cells" with raised in the enzymatic activity of GOT, GPT and alkaline phosphatase with no changes in turbidity tests and bilirrubinemia, in all reactional patients. The physiopathology of this problem and the types III and IV hypersensitivity phenomena are discussed.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo1980-11-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3610310.47878/hi.1980.v5.36103Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 5 No. 2 (1980); 93-111Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 5 n. 2 (1980); 93-1111982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLspahttps://periodicos.saude.sp.gov.br/hansenologia/article/view/36103/34413https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPacin, AnaFliess, Enrique L.Llorente, Berta E2023-11-29T13:59:42Zoai:ojs.periodicos.saude.sp.gov.br:article/36103Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2023-11-29T13:59:42Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false
dc.title.none.fl_str_mv La función hepática através del espectro clinico de la hanseniasis
title La función hepática através del espectro clinico de la hanseniasis
spellingShingle La función hepática através del espectro clinico de la hanseniasis
Pacin, Ana
Hanseniasis
Enzymatic activity
Liver function tests
Hanseniasis
Actividad enzimática
Pruebas de función hepática
title_short La función hepática através del espectro clinico de la hanseniasis
title_full La función hepática através del espectro clinico de la hanseniasis
title_fullStr La función hepática através del espectro clinico de la hanseniasis
title_full_unstemmed La función hepática através del espectro clinico de la hanseniasis
title_sort La función hepática através del espectro clinico de la hanseniasis
author Pacin, Ana
author_facet Pacin, Ana
Fliess, Enrique L.
Llorente, Berta E
author_role author
author2 Fliess, Enrique L.
Llorente, Berta E
author2_role author
author
dc.contributor.author.fl_str_mv Pacin, Ana
Fliess, Enrique L.
Llorente, Berta E
dc.subject.por.fl_str_mv Hanseniasis
Enzymatic activity
Liver function tests
Hanseniasis
Actividad enzimática
Pruebas de función hepática
topic Hanseniasis
Enzymatic activity
Liver function tests
Hanseniasis
Actividad enzimática
Pruebas de función hepática
description The liver function was studied in 100 hanseniasis patients. They were classified in the following 10 groups: quiescent LL (20 patients), quiescent BL (13 patients), quiescent BB (7 patients), quiescent BT (9 patients), quiescent TT (12 patients), reactional LL (12 patients), reactional BL (10 patients), reactional BB (7 patients) 4 reactional BT (5 patients), reactional TT (5 patients); a comparison was made with a control group (10 healthy individuals). It was found a hyperproteinemia with high levels of globulin and normal levels of albumin in the serum of all clinical forms, and a typical pattern of "light damage hepatic cells" with raised in the enzymatic activity of GOT, GPT and alkaline phosphatase with no changes in turbidity tests and bilirrubinemia, in all reactional patients. The physiopathology of this problem and the types III and IV hypersensitivity phenomena are discussed.
publishDate 1980
dc.date.none.fl_str_mv 1980-11-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/36103
10.47878/hi.1980.v5.36103
url https://periodicos.saude.sp.gov.br/hansenologia/article/view/36103
identifier_str_mv 10.47878/hi.1980.v5.36103
dc.language.iso.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/36103/34413
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
dc.source.none.fl_str_mv Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 5 No. 2 (1980); 93-111
Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 5 n. 2 (1980); 93-111
1982-5161
reponame:Hansenologia Internationalis (Online)
instname:Instituto Lauro de Souza Lima (ILSL)
instacron:ILSL
instname_str Instituto Lauro de Souza Lima (ILSL)
instacron_str ILSL
institution ILSL
reponame_str Hansenologia Internationalis (Online)
collection Hansenologia Internationalis (Online)
repository.name.fl_str_mv Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)
repository.mail.fl_str_mv hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br
_version_ 1796797580530679808

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