La función hepática através del espectro clinico de la hanseniasis
Autor(a) principal: | |
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Data de Publicação: | 1980 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | spa |
Título da fonte: | Hansenologia Internationalis (Online) |
Texto Completo: | https://periodicos.saude.sp.gov.br/hansenologia/article/view/36103 |
Resumo: | The liver function was studied in 100 hanseniasis patients. They were classified in the following 10 groups: quiescent LL (20 patients), quiescent BL (13 patients), quiescent BB (7 patients), quiescent BT (9 patients), quiescent TT (12 patients), reactional LL (12 patients), reactional BL (10 patients), reactional BB (7 patients) 4 reactional BT (5 patients), reactional TT (5 patients); a comparison was made with a control group (10 healthy individuals). It was found a hyperproteinemia with high levels of globulin and normal levels of albumin in the serum of all clinical forms, and a typical pattern of "light damage hepatic cells" with raised in the enzymatic activity of GOT, GPT and alkaline phosphatase with no changes in turbidity tests and bilirrubinemia, in all reactional patients. The physiopathology of this problem and the types III and IV hypersensitivity phenomena are discussed. |
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La función hepática através del espectro clinico de la hanseniasisHanseniasisEnzymatic activityLiver function testsHanseniasisActividad enzimáticaPruebas de función hepáticaThe liver function was studied in 100 hanseniasis patients. They were classified in the following 10 groups: quiescent LL (20 patients), quiescent BL (13 patients), quiescent BB (7 patients), quiescent BT (9 patients), quiescent TT (12 patients), reactional LL (12 patients), reactional BL (10 patients), reactional BB (7 patients) 4 reactional BT (5 patients), reactional TT (5 patients); a comparison was made with a control group (10 healthy individuals). It was found a hyperproteinemia with high levels of globulin and normal levels of albumin in the serum of all clinical forms, and a typical pattern of "light damage hepatic cells" with raised in the enzymatic activity of GOT, GPT and alkaline phosphatase with no changes in turbidity tests and bilirrubinemia, in all reactional patients. The physiopathology of this problem and the types III and IV hypersensitivity phenomena are discussed.Se estudie la función hepática en 100 pacientes hansenianos agrupados segtin la clasificación espectral y la presencia o no de episodios reaccionales del siguiente modo; pacientes quiescentes: 20 LL, 13 BL, 7 BB, 9 BT, 12 TT. Pacientes reaccionales: 12 LL, 10 BL, 7 BB, 5 BT, 5 TT. Como grupo testigo se estudiaron 10 individuos sanos no contactantes con pacientes hansenianos y sin antecedentes de patología hepática. Los resultados obtenidos muestran una hiperproteinemia a expensas de las globulinas sin disminución de albúmina en todas las formas clínicas de la hanseniasis, reaccionales y quiescentes, y un aumento de la actividad enzimática sérica de GPT, GOT y fosfatasa alcalina en los pacientes reacciónales. Estos incrementos de la actividad enzimática caracterizan un daño hepatocelular leve, en que la bilirruhinemia y la prueba de turbidez del timol no presentan alteraciones. Se discuten los mecanismos fisiopatológicos causantes de estas alteraciones, postulándose su vinculación con fenómenos de hipersensibilidad a tipo III y IV.The liver function was studied in 100 hanseniasis patients. They were classified in the following 10 groups: quiescent LL (20 patients), quiescent BL (13 patients), quiescent BB (7 patients), quiescent BT (9 patients), quiescent TT (12 patients), reactional LL (12 patients), reactional BL (10 patients), reactional BB (7 patients) 4 reactional BT (5 patients), reactional TT (5 patients); a comparison was made with a control group (10 healthy individuals). It was found a hyperproteinemia with high levels of globulin and normal levels of albumin in the serum of all clinical forms, and a typical pattern of "light damage hepatic cells" with raised in the enzymatic activity of GOT, GPT and alkaline phosphatase with no changes in turbidity tests and bilirrubinemia, in all reactional patients. The physiopathology of this problem and the types III and IV hypersensitivity phenomena are discussed.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo1980-11-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3610310.47878/hi.1980.v5.36103Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 5 No. 2 (1980); 93-111Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 5 n. 2 (1980); 93-1111982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLspahttps://periodicos.saude.sp.gov.br/hansenologia/article/view/36103/34413https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPacin, AnaFliess, Enrique L.Llorente, Berta E2023-11-29T13:59:42Zoai:ojs.periodicos.saude.sp.gov.br:article/36103Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2023-11-29T13:59:42Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false |
dc.title.none.fl_str_mv |
La función hepática através del espectro clinico de la hanseniasis |
title |
La función hepática através del espectro clinico de la hanseniasis |
spellingShingle |
La función hepática através del espectro clinico de la hanseniasis Pacin, Ana Hanseniasis Enzymatic activity Liver function tests Hanseniasis Actividad enzimática Pruebas de función hepática |
title_short |
La función hepática através del espectro clinico de la hanseniasis |
title_full |
La función hepática através del espectro clinico de la hanseniasis |
title_fullStr |
La función hepática através del espectro clinico de la hanseniasis |
title_full_unstemmed |
La función hepática através del espectro clinico de la hanseniasis |
title_sort |
La función hepática através del espectro clinico de la hanseniasis |
author |
Pacin, Ana |
author_facet |
Pacin, Ana Fliess, Enrique L. Llorente, Berta E |
author_role |
author |
author2 |
Fliess, Enrique L. Llorente, Berta E |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Pacin, Ana Fliess, Enrique L. Llorente, Berta E |
dc.subject.por.fl_str_mv |
Hanseniasis Enzymatic activity Liver function tests Hanseniasis Actividad enzimática Pruebas de función hepática |
topic |
Hanseniasis Enzymatic activity Liver function tests Hanseniasis Actividad enzimática Pruebas de función hepática |
description |
The liver function was studied in 100 hanseniasis patients. They were classified in the following 10 groups: quiescent LL (20 patients), quiescent BL (13 patients), quiescent BB (7 patients), quiescent BT (9 patients), quiescent TT (12 patients), reactional LL (12 patients), reactional BL (10 patients), reactional BB (7 patients) 4 reactional BT (5 patients), reactional TT (5 patients); a comparison was made with a control group (10 healthy individuals). It was found a hyperproteinemia with high levels of globulin and normal levels of albumin in the serum of all clinical forms, and a typical pattern of "light damage hepatic cells" with raised in the enzymatic activity of GOT, GPT and alkaline phosphatase with no changes in turbidity tests and bilirrubinemia, in all reactional patients. The physiopathology of this problem and the types III and IV hypersensitivity phenomena are discussed. |
publishDate |
1980 |
dc.date.none.fl_str_mv |
1980-11-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/36103 10.47878/hi.1980.v5.36103 |
url |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/36103 |
identifier_str_mv |
10.47878/hi.1980.v5.36103 |
dc.language.iso.fl_str_mv |
spa |
language |
spa |
dc.relation.none.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/36103/34413 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
dc.source.none.fl_str_mv |
Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 5 No. 2 (1980); 93-111 Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 5 n. 2 (1980); 93-111 1982-5161 reponame:Hansenologia Internationalis (Online) instname:Instituto Lauro de Souza Lima (ILSL) instacron:ILSL |
instname_str |
Instituto Lauro de Souza Lima (ILSL) |
instacron_str |
ILSL |
institution |
ILSL |
reponame_str |
Hansenologia Internationalis (Online) |
collection |
Hansenologia Internationalis (Online) |
repository.name.fl_str_mv |
Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL) |
repository.mail.fl_str_mv |
hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br |
_version_ |
1796797580530679808 |