Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis

Detalhes bibliográficos
Autor(a) principal: Silva, Marcos V
Data de Publicação: 1996
Outros Autores: Camargo, Eide D, Batista, Luíza, Vaz, Adelaide J, Ferreira, Antonio W, Barbosa, Paulo R.S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/29354
Resumo: Leptospirosis is one of the causes of meningitis, although its importance is not well known. In the present study we contributed to this knowledge by demonstrating specific IgM class anti-leptospira antibodies by the immunoenzymatic method ELISA in 14.6% of cerebrospinal fluid (CSF) samples from 171 patients with meningitis considered to be of indeterminate etiology. The frequencies of positivity were similar in cases with predominance of polymorphonuclear or lymphomononuclear leucocytes in the CSF. Age distribution showed a predominance of the 5 to 15 year age range (72%), and sex distribution showed a predominance of males (68%). The authors discuss the contribution of this method to the etiologic elucidation of meningitis.
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spelling Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis Aplicação do ELISA-IgM anti-leptospira na elucidação etiológica das meningites LeptospirosisMeningitis and ELISA-IgM Leptospirosis is one of the causes of meningitis, although its importance is not well known. In the present study we contributed to this knowledge by demonstrating specific IgM class anti-leptospira antibodies by the immunoenzymatic method ELISA in 14.6% of cerebrospinal fluid (CSF) samples from 171 patients with meningitis considered to be of indeterminate etiology. The frequencies of positivity were similar in cases with predominance of polymorphonuclear or lymphomononuclear leucocytes in the CSF. Age distribution showed a predominance of the 5 to 15 year age range (72%), and sex distribution showed a predominance of males (68%). The authors discuss the contribution of this method to the etiologic elucidation of meningitis. A Leptospirose é uma das causas de meningite, embora sua importância seja pouco conhecida. O presente estudo contribui para este conhecimento ao demonstrar anticorpos específicos da classe IgM anti-Leptospira pelo método imunoenzimático (ELISA), em 14,6% das amostras de líqüido cefalorraquianos (LCR) de 171 pacientes com meningite considerada de etiología indeterminada. As freqüências de positividade foram parecidas nos casos com predomínio no LCR de leucócitos polimorfonucleares ou linfomononucleares. A distribuição por idade mostrou predomínio na faixa etária entre 5 e 15 anos (72%) e por sexo o predomínio do masculino (68%). Os autores discutem a contribuição desse método na elucidação etiológica das meningites. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1996-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/29354Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 No. 2 (1996); 153-156 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 Núm. 2 (1996); 153-156 Revista do Instituto de Medicina Tropical de São Paulo; v. 38 n. 2 (1996); 153-156 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/29354/31211Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessSilva, Marcos VCamargo, Eide DBatista, LuízaVaz, Adelaide JFerreira, Antonio WBarbosa, Paulo R.S.2012-07-02T01:43:23Zoai:revistas.usp.br:article/29354Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:51:06.174425Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis
Aplicação do ELISA-IgM anti-leptospira na elucidação etiológica das meningites
title Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis
spellingShingle Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis
Silva, Marcos V
Leptospirosis
Meningitis and ELISA-IgM
title_short Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis
title_full Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis
title_fullStr Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis
title_full_unstemmed Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis
title_sort Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis
author Silva, Marcos V
author_facet Silva, Marcos V
Camargo, Eide D
Batista, Luíza
Vaz, Adelaide J
Ferreira, Antonio W
Barbosa, Paulo R.S.
author_role author
author2 Camargo, Eide D
Batista, Luíza
Vaz, Adelaide J
Ferreira, Antonio W
Barbosa, Paulo R.S.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Marcos V
Camargo, Eide D
Batista, Luíza
Vaz, Adelaide J
Ferreira, Antonio W
Barbosa, Paulo R.S.
dc.subject.por.fl_str_mv Leptospirosis
Meningitis and ELISA-IgM
topic Leptospirosis
Meningitis and ELISA-IgM
description Leptospirosis is one of the causes of meningitis, although its importance is not well known. In the present study we contributed to this knowledge by demonstrating specific IgM class anti-leptospira antibodies by the immunoenzymatic method ELISA in 14.6% of cerebrospinal fluid (CSF) samples from 171 patients with meningitis considered to be of indeterminate etiology. The frequencies of positivity were similar in cases with predominance of polymorphonuclear or lymphomononuclear leucocytes in the CSF. Age distribution showed a predominance of the 5 to 15 year age range (72%), and sex distribution showed a predominance of males (68%). The authors discuss the contribution of this method to the etiologic elucidation of meningitis.
publishDate 1996
dc.date.none.fl_str_mv 1996-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/29354
url https://www.revistas.usp.br/rimtsp/article/view/29354
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/29354/31211
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 No. 2 (1996); 153-156
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 Núm. 2 (1996); 153-156
Revista do Instituto de Medicina Tropical de São Paulo; v. 38 n. 2 (1996); 153-156
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
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institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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