Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis
Autor(a) principal: | |
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Data de Publicação: | 1996 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/29354 |
Resumo: | Leptospirosis is one of the causes of meningitis, although its importance is not well known. In the present study we contributed to this knowledge by demonstrating specific IgM class anti-leptospira antibodies by the immunoenzymatic method ELISA in 14.6% of cerebrospinal fluid (CSF) samples from 171 patients with meningitis considered to be of indeterminate etiology. The frequencies of positivity were similar in cases with predominance of polymorphonuclear or lymphomononuclear leucocytes in the CSF. Age distribution showed a predominance of the 5 to 15 year age range (72%), and sex distribution showed a predominance of males (68%). The authors discuss the contribution of this method to the etiologic elucidation of meningitis. |
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Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis Aplicação do ELISA-IgM anti-leptospira na elucidação etiológica das meningites LeptospirosisMeningitis and ELISA-IgM Leptospirosis is one of the causes of meningitis, although its importance is not well known. In the present study we contributed to this knowledge by demonstrating specific IgM class anti-leptospira antibodies by the immunoenzymatic method ELISA in 14.6% of cerebrospinal fluid (CSF) samples from 171 patients with meningitis considered to be of indeterminate etiology. The frequencies of positivity were similar in cases with predominance of polymorphonuclear or lymphomononuclear leucocytes in the CSF. Age distribution showed a predominance of the 5 to 15 year age range (72%), and sex distribution showed a predominance of males (68%). The authors discuss the contribution of this method to the etiologic elucidation of meningitis. A Leptospirose é uma das causas de meningite, embora sua importância seja pouco conhecida. O presente estudo contribui para este conhecimento ao demonstrar anticorpos específicos da classe IgM anti-Leptospira pelo método imunoenzimático (ELISA), em 14,6% das amostras de líqüido cefalorraquianos (LCR) de 171 pacientes com meningite considerada de etiología indeterminada. As freqüências de positividade foram parecidas nos casos com predomínio no LCR de leucócitos polimorfonucleares ou linfomononucleares. A distribuição por idade mostrou predomínio na faixa etária entre 5 e 15 anos (72%) e por sexo o predomínio do masculino (68%). Os autores discutem a contribuição desse método na elucidação etiológica das meningites. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1996-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/29354Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 No. 2 (1996); 153-156 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 Núm. 2 (1996); 153-156 Revista do Instituto de Medicina Tropical de São Paulo; v. 38 n. 2 (1996); 153-156 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/29354/31211Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessSilva, Marcos VCamargo, Eide DBatista, LuízaVaz, Adelaide JFerreira, Antonio WBarbosa, Paulo R.S.2012-07-02T01:43:23Zoai:revistas.usp.br:article/29354Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:51:06.174425Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis Aplicação do ELISA-IgM anti-leptospira na elucidação etiológica das meningites |
title |
Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis |
spellingShingle |
Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis Silva, Marcos V Leptospirosis Meningitis and ELISA-IgM |
title_short |
Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis |
title_full |
Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis |
title_fullStr |
Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis |
title_full_unstemmed |
Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis |
title_sort |
Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis |
author |
Silva, Marcos V |
author_facet |
Silva, Marcos V Camargo, Eide D Batista, Luíza Vaz, Adelaide J Ferreira, Antonio W Barbosa, Paulo R.S. |
author_role |
author |
author2 |
Camargo, Eide D Batista, Luíza Vaz, Adelaide J Ferreira, Antonio W Barbosa, Paulo R.S. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Silva, Marcos V Camargo, Eide D Batista, Luíza Vaz, Adelaide J Ferreira, Antonio W Barbosa, Paulo R.S. |
dc.subject.por.fl_str_mv |
Leptospirosis Meningitis and ELISA-IgM |
topic |
Leptospirosis Meningitis and ELISA-IgM |
description |
Leptospirosis is one of the causes of meningitis, although its importance is not well known. In the present study we contributed to this knowledge by demonstrating specific IgM class anti-leptospira antibodies by the immunoenzymatic method ELISA in 14.6% of cerebrospinal fluid (CSF) samples from 171 patients with meningitis considered to be of indeterminate etiology. The frequencies of positivity were similar in cases with predominance of polymorphonuclear or lymphomononuclear leucocytes in the CSF. Age distribution showed a predominance of the 5 to 15 year age range (72%), and sex distribution showed a predominance of males (68%). The authors discuss the contribution of this method to the etiologic elucidation of meningitis. |
publishDate |
1996 |
dc.date.none.fl_str_mv |
1996-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/29354 |
url |
https://www.revistas.usp.br/rimtsp/article/view/29354 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/29354/31211 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 No. 2 (1996); 153-156 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 Núm. 2 (1996); 153-156 Revista do Instituto de Medicina Tropical de São Paulo; v. 38 n. 2 (1996); 153-156 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
||revimtsp@usp.br |
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1798951642220986368 |