Quality of life in Brazilian patients with treated or untreated chronic hepatitis C

Detalhes bibliográficos
Autor(a) principal: Perlin, Cássio Marques
Data de Publicação: 2017
Outros Autores: Ferreira, Vinicius Lins, Borba, Helena Hiemisch Lobo, Wiens, Astrid, Ivantes, Cláudia Alexandra Pontes, Lenzi, Luana, Pontarolo, Roberto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/143754
Resumo: Introduction: Multiple factors negatively affect the quality of life of patients infected with hepatitis C virus. This study aims to evaluate the effect of pharmacological treatment on the quality of life of these individuals. Methods: This is a cross-sectional study conducted in two Southern Brazilian centers that used two instruments (a generic and a specific one) for measuring the quality of life in patients with chronic hepatitis C: the Short Form-36 (SF-36); and the Chronic Liver Disease Questionnaire (CLDQ) for liver disease. We included patients from two centers without any treatment (control group), or receiving medication (peginterferon + ribavirin ± telaprevir or boceprevir, i.e., respectively, dual, and triple therapies). Results: One hundred and forty-seven patients were included. Patients under treatment (n = 86) had a lower score in 7 of the 8 SF-36 domains, with statistical significance (p
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spelling Quality of life in Brazilian patients with treated or untreated chronic hepatitis CQuality of lifeHepatitis C treatmentSF-36CLDQ Introduction: Multiple factors negatively affect the quality of life of patients infected with hepatitis C virus. This study aims to evaluate the effect of pharmacological treatment on the quality of life of these individuals. Methods: This is a cross-sectional study conducted in two Southern Brazilian centers that used two instruments (a generic and a specific one) for measuring the quality of life in patients with chronic hepatitis C: the Short Form-36 (SF-36); and the Chronic Liver Disease Questionnaire (CLDQ) for liver disease. We included patients from two centers without any treatment (control group), or receiving medication (peginterferon + ribavirin ± telaprevir or boceprevir, i.e., respectively, dual, and triple therapies). Results: One hundred and forty-seven patients were included. Patients under treatment (n = 86) had a lower score in 7 of the 8 SF-36 domains, with statistical significance (pUniversidade de São Paulo. Instituto de Medicina Tropical de São Paulo2017-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/143754Revista do Instituto de Medicina Tropical de São Paulo; Vol. 59 (2017); e81Revista do Instituto de Medicina Tropical de São Paulo; Vol. 59 (2017); e81Revista do Instituto de Medicina Tropical de São Paulo; v. 59 (2017); e811678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/143754/138401Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessPerlin, Cássio MarquesFerreira, Vinicius LinsBorba, Helena Hiemisch LoboWiens, AstridIvantes, Cláudia Alexandra PontesLenzi, LuanaPontarolo, Roberto2018-02-23T18:46:02Zoai:revistas.usp.br:article/143754Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:52:42.770042Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Quality of life in Brazilian patients with treated or untreated chronic hepatitis C
title Quality of life in Brazilian patients with treated or untreated chronic hepatitis C
spellingShingle Quality of life in Brazilian patients with treated or untreated chronic hepatitis C
Perlin, Cássio Marques
Quality of life
Hepatitis C treatment
SF-36
CLDQ
title_short Quality of life in Brazilian patients with treated or untreated chronic hepatitis C
title_full Quality of life in Brazilian patients with treated or untreated chronic hepatitis C
title_fullStr Quality of life in Brazilian patients with treated or untreated chronic hepatitis C
title_full_unstemmed Quality of life in Brazilian patients with treated or untreated chronic hepatitis C
title_sort Quality of life in Brazilian patients with treated or untreated chronic hepatitis C
author Perlin, Cássio Marques
author_facet Perlin, Cássio Marques
Ferreira, Vinicius Lins
Borba, Helena Hiemisch Lobo
Wiens, Astrid
Ivantes, Cláudia Alexandra Pontes
Lenzi, Luana
Pontarolo, Roberto
author_role author
author2 Ferreira, Vinicius Lins
Borba, Helena Hiemisch Lobo
Wiens, Astrid
Ivantes, Cláudia Alexandra Pontes
Lenzi, Luana
Pontarolo, Roberto
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Perlin, Cássio Marques
Ferreira, Vinicius Lins
Borba, Helena Hiemisch Lobo
Wiens, Astrid
Ivantes, Cláudia Alexandra Pontes
Lenzi, Luana
Pontarolo, Roberto
dc.subject.por.fl_str_mv Quality of life
Hepatitis C treatment
SF-36
CLDQ
topic Quality of life
Hepatitis C treatment
SF-36
CLDQ
description Introduction: Multiple factors negatively affect the quality of life of patients infected with hepatitis C virus. This study aims to evaluate the effect of pharmacological treatment on the quality of life of these individuals. Methods: This is a cross-sectional study conducted in two Southern Brazilian centers that used two instruments (a generic and a specific one) for measuring the quality of life in patients with chronic hepatitis C: the Short Form-36 (SF-36); and the Chronic Liver Disease Questionnaire (CLDQ) for liver disease. We included patients from two centers without any treatment (control group), or receiving medication (peginterferon + ribavirin ± telaprevir or boceprevir, i.e., respectively, dual, and triple therapies). Results: One hundred and forty-seven patients were included. Patients under treatment (n = 86) had a lower score in 7 of the 8 SF-36 domains, with statistical significance (p
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/143754
url https://www.revistas.usp.br/rimtsp/article/view/143754
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/143754/138401
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 59 (2017); e81
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 59 (2017); e81
Revista do Instituto de Medicina Tropical de São Paulo; v. 59 (2017); e81
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
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reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
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