Acute pancreatitis associated with multibacillary polychemotherapy for leprosy
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/191803 |
Resumo: | Acute pancreatitis (AP) is an inflammatory disease associated with abdominal pain and elevated serum pancreatic enzymes. The most common etiologies are gallstones and alcoholism. Drug-induced AP is quite rare, lacks a solid understanding and has been occasionally reported. The diagnosis requires a great suspicion and a careful exclusion of other causes. We present a case of a 37-year-old man, previously diagnosed with leprosy that developed acute pancreatitis after starting the multibacillary polychemotherapy (PCT/MB). After a month of treatment and the discontinuation of the PCT/MB, the therapy was restarted and a new episode of AP occurred. Three months after this last episode, the PCT/MB was reintroduced, changing one of the medications and the patient had no recurrence of AP or other reactions. Therefore, it is important to take into account that there is a risk of acute pancreatitis in patients on multidrug therapy (MDT) for leprosy. |
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Acute pancreatitis associated with multibacillary polychemotherapy for leprosyPancreatitisLeprosyMultibaccilary polychemotherapyDapsoneRifampicinAcute pancreatitis (AP) is an inflammatory disease associated with abdominal pain and elevated serum pancreatic enzymes. The most common etiologies are gallstones and alcoholism. Drug-induced AP is quite rare, lacks a solid understanding and has been occasionally reported. The diagnosis requires a great suspicion and a careful exclusion of other causes. We present a case of a 37-year-old man, previously diagnosed with leprosy that developed acute pancreatitis after starting the multibacillary polychemotherapy (PCT/MB). After a month of treatment and the discontinuation of the PCT/MB, the therapy was restarted and a new episode of AP occurred. Three months after this last episode, the PCT/MB was reintroduced, changing one of the medications and the patient had no recurrence of AP or other reactions. Therefore, it is important to take into account that there is a risk of acute pancreatitis in patients on multidrug therapy (MDT) for leprosy.Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2021-10-26info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/19180310.1590/S1678-9946202163073Revista do Instituto de Medicina Tropical de São Paulo; Vol. 63 (2021); e73Revista do Instituto de Medicina Tropical de São Paulo; Vol. 63 (2021); e73Revista do Instituto de Medicina Tropical de São Paulo; v. 63 (2021); e731678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/191803/176710Copyright (c) 2021 Lucas Guimarães Maciel, Lucas Ataídes Amorim França, Bárbara Veloso de Deus, Caio César Siqueira Formigahttps://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessMaciel, Lucas Guimarães França, Lucas Ataídes Amorim Deus, Bárbara Veloso de Formiga, Caio César Siqueira 2022-05-16T13:44:35Zoai:revistas.usp.br:article/191803Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:53:00.005794Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
Acute pancreatitis associated with multibacillary polychemotherapy for leprosy |
title |
Acute pancreatitis associated with multibacillary polychemotherapy for leprosy |
spellingShingle |
Acute pancreatitis associated with multibacillary polychemotherapy for leprosy Maciel, Lucas Guimarães Pancreatitis Leprosy Multibaccilary polychemotherapy Dapsone Rifampicin |
title_short |
Acute pancreatitis associated with multibacillary polychemotherapy for leprosy |
title_full |
Acute pancreatitis associated with multibacillary polychemotherapy for leprosy |
title_fullStr |
Acute pancreatitis associated with multibacillary polychemotherapy for leprosy |
title_full_unstemmed |
Acute pancreatitis associated with multibacillary polychemotherapy for leprosy |
title_sort |
Acute pancreatitis associated with multibacillary polychemotherapy for leprosy |
author |
Maciel, Lucas Guimarães |
author_facet |
Maciel, Lucas Guimarães França, Lucas Ataídes Amorim Deus, Bárbara Veloso de Formiga, Caio César Siqueira |
author_role |
author |
author2 |
França, Lucas Ataídes Amorim Deus, Bárbara Veloso de Formiga, Caio César Siqueira |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Maciel, Lucas Guimarães França, Lucas Ataídes Amorim Deus, Bárbara Veloso de Formiga, Caio César Siqueira |
dc.subject.por.fl_str_mv |
Pancreatitis Leprosy Multibaccilary polychemotherapy Dapsone Rifampicin |
topic |
Pancreatitis Leprosy Multibaccilary polychemotherapy Dapsone Rifampicin |
description |
Acute pancreatitis (AP) is an inflammatory disease associated with abdominal pain and elevated serum pancreatic enzymes. The most common etiologies are gallstones and alcoholism. Drug-induced AP is quite rare, lacks a solid understanding and has been occasionally reported. The diagnosis requires a great suspicion and a careful exclusion of other causes. We present a case of a 37-year-old man, previously diagnosed with leprosy that developed acute pancreatitis after starting the multibacillary polychemotherapy (PCT/MB). After a month of treatment and the discontinuation of the PCT/MB, the therapy was restarted and a new episode of AP occurred. Three months after this last episode, the PCT/MB was reintroduced, changing one of the medications and the patient had no recurrence of AP or other reactions. Therefore, it is important to take into account that there is a risk of acute pancreatitis in patients on multidrug therapy (MDT) for leprosy. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-10-26 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/191803 10.1590/S1678-9946202163073 |
url |
https://www.revistas.usp.br/rimtsp/article/view/191803 |
identifier_str_mv |
10.1590/S1678-9946202163073 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/191803/176710 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 63 (2021); e73 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 63 (2021); e73 Revista do Instituto de Medicina Tropical de São Paulo; v. 63 (2021); e73 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
||revimtsp@usp.br |
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1798951653728059392 |