Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice

Detalhes bibliográficos
Autor(a) principal: Takeda, Gentilda K. F.
Data de Publicação: 1986
Outros Autores: Campos, Rubens, Kieffer, Julio, Moreira, Antonio Augusto B., Amato Neto, Vicente, Castilho, Vera Lúcia P., Pinto, Pedro Luiz S., Duarte, Maria Irma Seixas
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/87457
Resumo: Blood samples of animals infected with T. cruzi — Y strain, were submitted to gamma radiation in dosage of 200 and 300 krad. In order to verify the efficacy of this method to eliminante the parasite the blood samples were inoculated in to mice and the following parameters were used: parasitemia, hemoculture, xenodiagnosis, subinoculaticn, reinoculation of mice with a virulent strain and anatomy pathological study. The blood samples exposed to the different radiation dosages and inoculated at two different periods were unable to induce a subsequent infection in all animals tested.
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spelling Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice Ação de raios gama sobre formas sanguícolas de Trypanosoma cruzi: estudo experimental em camundongos Blood samples of animals infected with T. cruzi — Y strain, were submitted to gamma radiation in dosage of 200 and 300 krad. In order to verify the efficacy of this method to eliminante the parasite the blood samples were inoculated in to mice and the following parameters were used: parasitemia, hemoculture, xenodiagnosis, subinoculaticn, reinoculation of mice with a virulent strain and anatomy pathological study. The blood samples exposed to the different radiation dosages and inoculated at two different periods were unable to induce a subsequent infection in all animals tested. Amostras de sangue de animais infectados com cepa Y de Trypanosoma cruzi foram submetidas, respectivamente, a 200 e 300 krad de radiação gama. Para verificar a eficácia do método na eliminação do parasita, o material foi inoculado em camundongos e os parâmetros utilizados na avaliação foram: parasitemia, cultura, xenodiagnóstico, subinoculação, reinoculação com cepa virulenta e exame anátomo-patológico das vísceras. Os sangues expostos às duas diferentes intensidades de radiação e inoculados em dois períodos após o processo, mostraram-se inócuos quanto a capacidade de produzir infecção nos animais Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1986-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/87457Revista do Instituto de Medicina Tropical de São Paulo; Vol. 28 No. 1 (1986); 15-18Revista do Instituto de Medicina Tropical de São Paulo; Vol. 28 Núm. 1 (1986); 15-18Revista do Instituto de Medicina Tropical de São Paulo; v. 28 n. 1 (1986); 15-181678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTporhttps://www.revistas.usp.br/rimtsp/article/view/87457/90415Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessTakeda, Gentilda K. F.Campos, RubensKieffer, JulioMoreira, Antonio Augusto B.Amato Neto, VicenteCastilho, Vera Lúcia P.Pinto, Pedro Luiz S.Duarte, Maria Irma Seixas2015-07-29T17:02:24Zoai:revistas.usp.br:article/87457Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:52:25.699821Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice
Ação de raios gama sobre formas sanguícolas de Trypanosoma cruzi: estudo experimental em camundongos
title Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice
spellingShingle Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice
Takeda, Gentilda K. F.
title_short Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice
title_full Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice
title_fullStr Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice
title_full_unstemmed Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice
title_sort Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice
author Takeda, Gentilda K. F.
author_facet Takeda, Gentilda K. F.
Campos, Rubens
Kieffer, Julio
Moreira, Antonio Augusto B.
Amato Neto, Vicente
Castilho, Vera Lúcia P.
Pinto, Pedro Luiz S.
Duarte, Maria Irma Seixas
author_role author
author2 Campos, Rubens
Kieffer, Julio
Moreira, Antonio Augusto B.
Amato Neto, Vicente
Castilho, Vera Lúcia P.
Pinto, Pedro Luiz S.
Duarte, Maria Irma Seixas
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Takeda, Gentilda K. F.
Campos, Rubens
Kieffer, Julio
Moreira, Antonio Augusto B.
Amato Neto, Vicente
Castilho, Vera Lúcia P.
Pinto, Pedro Luiz S.
Duarte, Maria Irma Seixas
description Blood samples of animals infected with T. cruzi — Y strain, were submitted to gamma radiation in dosage of 200 and 300 krad. In order to verify the efficacy of this method to eliminante the parasite the blood samples were inoculated in to mice and the following parameters were used: parasitemia, hemoculture, xenodiagnosis, subinoculaticn, reinoculation of mice with a virulent strain and anatomy pathological study. The blood samples exposed to the different radiation dosages and inoculated at two different periods were unable to induce a subsequent infection in all animals tested.
publishDate 1986
dc.date.none.fl_str_mv 1986-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/87457
url https://www.revistas.usp.br/rimtsp/article/view/87457
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/87457/90415
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 28 No. 1 (1986); 15-18
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 28 Núm. 1 (1986); 15-18
Revista do Instituto de Medicina Tropical de São Paulo; v. 28 n. 1 (1986); 15-18
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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