Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice
Autor(a) principal: | |
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Data de Publicação: | 1986 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/87457 |
Resumo: | Blood samples of animals infected with T. cruzi Y strain, were submitted to gamma radiation in dosage of 200 and 300 krad. In order to verify the efficacy of this method to eliminante the parasite the blood samples were inoculated in to mice and the following parameters were used: parasitemia, hemoculture, xenodiagnosis, subinoculaticn, reinoculation of mice with a virulent strain and anatomy pathological study. The blood samples exposed to the different radiation dosages and inoculated at two different periods were unable to induce a subsequent infection in all animals tested. |
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Revista do Instituto de Medicina Tropical de São Paulo |
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Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice Ação de raios gama sobre formas sanguícolas de Trypanosoma cruzi: estudo experimental em camundongos Blood samples of animals infected with T. cruzi Y strain, were submitted to gamma radiation in dosage of 200 and 300 krad. In order to verify the efficacy of this method to eliminante the parasite the blood samples were inoculated in to mice and the following parameters were used: parasitemia, hemoculture, xenodiagnosis, subinoculaticn, reinoculation of mice with a virulent strain and anatomy pathological study. The blood samples exposed to the different radiation dosages and inoculated at two different periods were unable to induce a subsequent infection in all animals tested. Amostras de sangue de animais infectados com cepa Y de Trypanosoma cruzi foram submetidas, respectivamente, a 200 e 300 krad de radiação gama. Para verificar a eficácia do método na eliminação do parasita, o material foi inoculado em camundongos e os parâmetros utilizados na avaliação foram: parasitemia, cultura, xenodiagnóstico, subinoculação, reinoculação com cepa virulenta e exame anátomo-patológico das vísceras. Os sangues expostos às duas diferentes intensidades de radiação e inoculados em dois períodos após o processo, mostraram-se inócuos quanto a capacidade de produzir infecção nos animais Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1986-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/87457Revista do Instituto de Medicina Tropical de São Paulo; Vol. 28 No. 1 (1986); 15-18Revista do Instituto de Medicina Tropical de São Paulo; Vol. 28 Núm. 1 (1986); 15-18Revista do Instituto de Medicina Tropical de São Paulo; v. 28 n. 1 (1986); 15-181678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTporhttps://www.revistas.usp.br/rimtsp/article/view/87457/90415Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessTakeda, Gentilda K. F.Campos, RubensKieffer, JulioMoreira, Antonio Augusto B.Amato Neto, VicenteCastilho, Vera Lúcia P.Pinto, Pedro Luiz S.Duarte, Maria Irma Seixas2015-07-29T17:02:24Zoai:revistas.usp.br:article/87457Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:52:25.699821Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice Ação de raios gama sobre formas sanguícolas de Trypanosoma cruzi: estudo experimental em camundongos |
title |
Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice |
spellingShingle |
Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice Takeda, Gentilda K. F. |
title_short |
Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice |
title_full |
Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice |
title_fullStr |
Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice |
title_full_unstemmed |
Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice |
title_sort |
Action of gamma radiation on blood forms of Trypanosoma cruzi: experimental study in mice |
author |
Takeda, Gentilda K. F. |
author_facet |
Takeda, Gentilda K. F. Campos, Rubens Kieffer, Julio Moreira, Antonio Augusto B. Amato Neto, Vicente Castilho, Vera Lúcia P. Pinto, Pedro Luiz S. Duarte, Maria Irma Seixas |
author_role |
author |
author2 |
Campos, Rubens Kieffer, Julio Moreira, Antonio Augusto B. Amato Neto, Vicente Castilho, Vera Lúcia P. Pinto, Pedro Luiz S. Duarte, Maria Irma Seixas |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Takeda, Gentilda K. F. Campos, Rubens Kieffer, Julio Moreira, Antonio Augusto B. Amato Neto, Vicente Castilho, Vera Lúcia P. Pinto, Pedro Luiz S. Duarte, Maria Irma Seixas |
description |
Blood samples of animals infected with T. cruzi Y strain, were submitted to gamma radiation in dosage of 200 and 300 krad. In order to verify the efficacy of this method to eliminante the parasite the blood samples were inoculated in to mice and the following parameters were used: parasitemia, hemoculture, xenodiagnosis, subinoculaticn, reinoculation of mice with a virulent strain and anatomy pathological study. The blood samples exposed to the different radiation dosages and inoculated at two different periods were unable to induce a subsequent infection in all animals tested. |
publishDate |
1986 |
dc.date.none.fl_str_mv |
1986-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/87457 |
url |
https://www.revistas.usp.br/rimtsp/article/view/87457 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/87457/90415 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 28 No. 1 (1986); 15-18 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 28 Núm. 1 (1986); 15-18 Revista do Instituto de Medicina Tropical de São Paulo; v. 28 n. 1 (1986); 15-18 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
||revimtsp@usp.br |
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1798951650153463808 |