Pattern of mycobacterial antigen detection in leprosy

Detalhes bibliográficos
Autor(a) principal: Pagliari, C.
Data de Publicação: 1995
Outros Autores: Duarte, M. I. S., Sotto, M. N.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/29224
Resumo: Immunohistochemistry reaction (Peroxidase anti-peroxidase - PAP) was carried out on fifty-two skin biopsies from leprosy patients with the purpose to identify the antigenic pattern in mycobacteria and to study the sensitivity of this method. Five different patterns were found: bacillar, granular, vesicular, cytoplasmatic and deposits, classified according to the antigenic material characteristics. Deposits (thinely particulate material) appeared more frequently, confirming the immunohistochemistry sensitivity to detect small amounts of antigens even when this material is not detected by histochemical stainings.
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spelling Pattern of mycobacterial antigen detection in leprosy Detecção de padrões antigênicos de micobactérias na hanseníase ImmunohistochemistryLeprosyMycobacterial antigen Immunohistochemistry reaction (Peroxidase anti-peroxidase - PAP) was carried out on fifty-two skin biopsies from leprosy patients with the purpose to identify the antigenic pattern in mycobacteria and to study the sensitivity of this method. Five different patterns were found: bacillar, granular, vesicular, cytoplasmatic and deposits, classified according to the antigenic material characteristics. Deposits (thinely particulate material) appeared more frequently, confirming the immunohistochemistry sensitivity to detect small amounts of antigens even when this material is not detected by histochemical stainings. Foi realizada reação imunohistoquímica (Peroxidase anti-peroxidase-PAP) em 52 biópsias de pele de pacientes com hanseníase com o objetivo de verificar quais os padrões antigênicos das micobactérias e estudar a sensibilidade deste método como auxílio diagnóstico da hanseníase. Foram encontrados cinco padrões diferentes, classificados como bacilar, granular, vesicular, citoplasmático e depósitos, de acordo com a característica do material antigênico. Os depósitos (material finamente particulado) apareceram com maior frequencia confirmando a sensibilidade da imunohistoquímica na detecção de pequenas quantidades de antígeno, cujo material não é mais visto por colorações histoquímicas usuais. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1995-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/29224Revista do Instituto de Medicina Tropical de São Paulo; Vol. 37 No. 1 (1995); 7-12 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 37 Núm. 1 (1995); 7-12 Revista do Instituto de Medicina Tropical de São Paulo; v. 37 n. 1 (1995); 7-12 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/29224/31081Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessPagliari, C.Duarte, M. I. S.Sotto, M. N.2012-07-02T01:39:31Zoai:revistas.usp.br:article/29224Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:50:58.541113Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Pattern of mycobacterial antigen detection in leprosy
Detecção de padrões antigênicos de micobactérias na hanseníase
title Pattern of mycobacterial antigen detection in leprosy
spellingShingle Pattern of mycobacterial antigen detection in leprosy
Pagliari, C.
Immunohistochemistry
Leprosy
Mycobacterial antigen
title_short Pattern of mycobacterial antigen detection in leprosy
title_full Pattern of mycobacterial antigen detection in leprosy
title_fullStr Pattern of mycobacterial antigen detection in leprosy
title_full_unstemmed Pattern of mycobacterial antigen detection in leprosy
title_sort Pattern of mycobacterial antigen detection in leprosy
author Pagliari, C.
author_facet Pagliari, C.
Duarte, M. I. S.
Sotto, M. N.
author_role author
author2 Duarte, M. I. S.
Sotto, M. N.
author2_role author
author
dc.contributor.author.fl_str_mv Pagliari, C.
Duarte, M. I. S.
Sotto, M. N.
dc.subject.por.fl_str_mv Immunohistochemistry
Leprosy
Mycobacterial antigen
topic Immunohistochemistry
Leprosy
Mycobacterial antigen
description Immunohistochemistry reaction (Peroxidase anti-peroxidase - PAP) was carried out on fifty-two skin biopsies from leprosy patients with the purpose to identify the antigenic pattern in mycobacteria and to study the sensitivity of this method. Five different patterns were found: bacillar, granular, vesicular, cytoplasmatic and deposits, classified according to the antigenic material characteristics. Deposits (thinely particulate material) appeared more frequently, confirming the immunohistochemistry sensitivity to detect small amounts of antigens even when this material is not detected by histochemical stainings.
publishDate 1995
dc.date.none.fl_str_mv 1995-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/29224
url https://www.revistas.usp.br/rimtsp/article/view/29224
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/29224/31081
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 37 No. 1 (1995); 7-12
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 37 Núm. 1 (1995); 7-12
Revista do Instituto de Medicina Tropical de São Paulo; v. 37 n. 1 (1995); 7-12
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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