Gelatin particle indirect agglutination test for serodiagnosis of schistosomiasis: comparative study with enzyme-linked immunosorbent assay

• Autor(a) principal: Kobayashi, Jun
• Data de Publicação: 1994
• Outros Autores: Carrilho, Flair José, Shimabukuro, Tetsu, Silva, Luiz Caetano da, Soares, Elza Cotrim, Nishimura, Nancy Fusae, Chieffi, Pedro Paulo, Sato, Yoshiya
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
• Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/29189
• topic: Schistosoma mansoni; Serodiagnosis; GPAT (gelatin particle agglutination test); ELISA

A new serological test, the gelatin particle agglutination test (GPAT), was used for the serodiagnosis of schistosomiasis mansoni. This technique showed the sensitivity (90.6%) and specificity (97.8%) close to those of enzyme-linked immunosorbent assay. The GPAT can be easily and rapidly performed without specialized equipment, by using lyophilized antigen-coated gelatin particles. The test also seems to be useful for mass screening of Schistosoma infection in field conditions.