Meigs Syndrome: Case Report

• Autor(a) principal: Santos, Pedro Hugo Gouveia Azevedo dos
• Data de Publicação: 2023
• Outros Autores: Nunes, Paulo Henrique Silva, Lima, Letícia Raabe Mota de, Dias, Vinicius Quintanilha Gomes, Matos, Mariana Ferreira, Matos, Leandro Rodrigo Pereira de, Assunção, Robson Caetano Guedes, Castro Neto, Heládio Feitosa e
• Tipo de documento: Artigo
• Idioma: por; eng; spa
• Título da fonte: Revista Brasileira de Cancerologia (Online)
• Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/3939
• topic: síndrome de Meigs; fibroma; ascite; derrame pleural; oncologia cirúrgica; Meigs syndrome; fibroma; ascites; pleural effusion; surgical oncology; síndrome de Meigs; fibroma; ascitis; derrame pleural; oncología quirúrgica

Introduction: Meigs syndrome is a rare clinical condition, defined as the association of pleural effusion, ascites and ovarian fibroma, with resolution of symptoms after tumor resection. Case report: Female patient, 56 years old, with dry cough associated with hyporexia, weight loss and progressive dyspnea for one month. Chest X-ray and later chest tomography showed massive pleural effusion on the right. Thoracocentesis was performed with drainage of 2,500 ml of serous fluid, suggestive of exudate. On examination, a palpable mass was observed in the hypogastrium, with an upper limit in the umbilicus. Imaging exams show solid expansive formation of possible left ovarian origin and presence of ascitic fluid. The patient underwent total hysterectomy with bilateral salpingo-oophorectomy and resection of the pelvic mass. Intraoperatively, frozen section was suggestive of ovarian fibroma. Histopathological of the surgical specimen confirmed ovarian fibroma measuring 13.0 x 12.5 x 7.5 cm and cytopathological examination of the ascitic fluid was negative for neoplastic cells. The patient evolved in good general condition with resolution of the pleural effusion and ascites and continues without recurrence of symptoms. Conclusion: The definitive diagnosis is made by histological confirmation of ovarian fibroma and resolution of symptoms after removal of the tumor. Dyspnea may be the initial symptom and the CA-125 may be elevated. The prognosis is usually good and the chances of recurrence are minimal.