Giant Cell tumor of the Zygomatic Arch in a Pediatric Patient: Rare Case Report

• Autor(a) principal: Maffini, Jhulia Farinha
• Data de Publicação: 2022
• Outros Autores: De Lucca, Maria Eduarda Turczyn, Antunes, Leonardo Cesar Ferreira, Mazzo, Felipe Antonio Torres, Barcelos, Carlos Eliseu, Moraes, Rodrigo Leite de, Jaouhari, Eduardo Talib Bacchi, Kozonoe , Milena Massumi, Torres, Rosângela Stadnick Lauth de Almeida
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista Brasileira de Cancerologia (Online)
• Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/1880
• topic: tumor de células gigantes do osso; fossa craniana média; neoplasias cranianas; relatos de casos; giant cell tumor of bone; cranial fossa, middle; skull neoplasms; case reports; tumor óseo de células gigantes; fosa craneal media; neoplasias craneales; informes de casos

Introduction: A giant cell tumor (GCT) is a rare tumor, usually benign, which can be locally aggressive, with an almost unknown incidence in the skull. Case report: Case report of a pediatric patient diagnosed with Ewing’s sarcoma (ES) and later GCT when sought medical care for an increased volume in the zygomatic arch and the right preauricular region. Imaging exams showed an expansive lesion in the zygomatic and squamous portion of the right temporal bone, with an extradural intracranial component in the middle fossa, with no evidence of infiltration. From the anatomopathological view, fusocelullar neoplasia was seen. The CD68 marker was positive and the S100 marker was negative. Tumor resection by microsurgery was performed. The patient remains in follow-up, with imaging exams at neurosurgery and orthopedics, the latest magnetic resonances of the skull showing a reduction in the size of the lesion. In addition, the patient did not submit to adjuvant therapy and is currently without complaints. Conclusion: This is an important case due to its rarity and clinical data that contributes for the understanding of the pathologies presented, allowing that, in the future, new studies are able to optimize the treatment, and the prognosis for these patients.