Dosimetry Comparison of Radiotherapy Planning Techniques for Left Breast Cancer

Detalhes bibliográficos
Autor(a) principal: Prandi, Tatiane Mayla Domingos
Data de Publicação: 2023
Outros Autores: Zaias, Herofen, Silva , Charlene da, Müller , Juliana dos Santos, Blasius, Larissa Palhano da Silva, Dorow , Patrícia Fernanda
Tipo de documento: Artigo
Idioma: por
eng
spa
Título da fonte: Revista Brasileira de Cancerologia (Online)
DOI: 10.32635/2176-9745.RBC.2023v69n3.4020
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/4020
Resumo: Introduction: Radiotherapy is utilized to treat breast cancer. For radiotherapy planning, there are several ways to develop the treatment plan, such as 3D conformal radiotherapy (3D-CRT), intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT). Objective: To compare the doses to risk organs and treatment target volume with different planning techniques, 3D-CRT, IMRT, VMAT and modified VMAT for the treatment of breast cancer in an anthropomorphic phantom. Method: The treatment plan was performed in the Eclipse™ v.15.6 system by Varian from CT images acquired from phantom. The established prescription dose was 45 Gy in 25 fractions of 1.8Gy/day. Results: For the planning target volume (PTV) coverage, 3D-CRT techniques (FILTER and field-in-field – FIF) showed inferior coverage compared to IMRT and VMAT plans. The 3D-CRT-FIF plan, on the other hand, shows greater homogeneity when compared to 3D-CRT-FILTER. For the contralateral lung, the 3D-CRT plans (FIF, FILTER) have better restrictions when compared with the other plans. On cardiac exposure, the 3D-CRT (FIF, FILTER) plans showed greater benefits when compared with IMRT, VMAT and Modified VMAT techniques. Conclusion: Conventional 3D-CRT techniques (FIF, FILTER) showed lower doses in organs at risk. However, IMRT and VMAT techniques obtained better homogeneity and conformity of the dose delivered to the PTV when compared to conventional techniques.
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spelling Dosimetry Comparison of Radiotherapy Planning Techniques for Left Breast CancerComparación Dosimétrica entre Técnicas de Planificación de Radioterapia para el Cáncer de Mama IzquierdoComparação Dosimétrica entre Técnicas de Planejamento de Radioterapia para Câncer de Mama Esquerdaradioterapia conformacionalradioterapia de intensidade moduladaneoplasias da mamadoses de radiaçãoradiotherapy, conformalradiotherapy, intensity-modulatedbreast neoplasmsradiation dosageradioterapia conformacionalradioterapia de intensidad moduladaneoplasias de la mamadosis de radiaciónIntroduction: Radiotherapy is utilized to treat breast cancer. For radiotherapy planning, there are several ways to develop the treatment plan, such as 3D conformal radiotherapy (3D-CRT), intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT). Objective: To compare the doses to risk organs and treatment target volume with different planning techniques, 3D-CRT, IMRT, VMAT and modified VMAT for the treatment of breast cancer in an anthropomorphic phantom. Method: The treatment plan was performed in the Eclipse™ v.15.6 system by Varian from CT images acquired from phantom. The established prescription dose was 45 Gy in 25 fractions of 1.8Gy/day. Results: For the planning target volume (PTV) coverage, 3D-CRT techniques (FILTER and field-in-field – FIF) showed inferior coverage compared to IMRT and VMAT plans. The 3D-CRT-FIF plan, on the other hand, shows greater homogeneity when compared to 3D-CRT-FILTER. For the contralateral lung, the 3D-CRT plans (FIF, FILTER) have better restrictions when compared with the other plans. On cardiac exposure, the 3D-CRT (FIF, FILTER) plans showed greater benefits when compared with IMRT, VMAT and Modified VMAT techniques. Conclusion: Conventional 3D-CRT techniques (FIF, FILTER) showed lower doses in organs at risk. However, IMRT and VMAT techniques obtained better homogeneity and conformity of the dose delivered to the PTV when compared to conventional techniques.Introducción: La radioterapia se utiliza en el tratamiento del cáncer de mama. En la planificación de la radioterapia, existen formas de desarrollar el plan de tratamiento, como la radioterapia conformacional 3D (3D-CRT), la radioterapia de intensidad modulada (IMRT) y la arcoterapia volumétrica modulada (VMAT). Objetivo: Comparar las dosis en órganos de riesgo y en el volumen blanco de tratamiento con diferentes técnicas de planificación: 3D-CRT, IMRT, VMAT y VMAT modificada para el tratamiento del cáncer de mama en un fantoma antropomórfico. Método: El plan de tratamiento se realizó en el sistema Eclipse™ v.15.6 de Varian a partir de imágenes de TC adquiridas del fantoma. La dosis de prescripción establecida fue de 45 Gy en 25 fracciones de 1,8Gy/día. Resultados: En cuanto a la cobertura del volumen blanco de planificación (VBP), las técnicas 3D-CRT (filtro - FILTRO y field-in-field – FIF) demostraron una cobertura inferior en comparación con los planes IMRT y VMAT. El plan 3D-RCT-FIF mostró mayor homogeneidad en comparación con el 3D-RCT-FILTRO. Para el pulmón contralateral, los planes 3D-CRT (FIF, FILTER) obtuvieron mejores restricciones en comparación con los otros planes. En la exposición cardiaca, los planes 3D-CRT (FIF, FILTER) mostraron mayores beneficios en comparación con las técnicas IMRT, VMAT y VMAT modificada. Conclusión: Las técnicas convencionales de 3D-CRT (FIF, FILTER) mostraron dosis más bajas en los órganos de riesgo. Sin embargo, las técnicas IMRT y VMAT obtuvieron una mejor homogeneidad y conformidad de la dosis distribuida en el VBP en comparación con las técnicas convencionales.Introdução: A radioterapia é utilizada no tratamento de câncer de mama. No planejamento radioterápico, há formas de desenvolver o plano de tratamento, como a radioterapia 3D conformacional (3D-CRT), a radioterapia de intensidade modulada (IMRT) e a arcoterapia volumétrica modulada (VMAT). Objetivo: Comparar as doses nos órgãos de risco e no volume-alvo de tratamento com as diferentes técnicas de planejamento: 3D-CRT, IMRT, VMAT e VMAT modificada para o tratamento do câncer de mama em um phantom antropomórfico. Método: O plano de tratamento foi realizado no sistema Eclipse™ v.15.6 da Varian a partir de imagens de tomografia computadorizada adquiridas de phantom. A dose de prescrição estabelecida foi de 45 Gy em 25 frações de 1,8 Gy/dia. Resultados: Sobre a cobertura do volume do alvo planejado (PTV), as técnicas 3D-CRT (FILTRO e field-in-field – FIF) demonstram cobertura inferior comparada aos planos de IMRT e VMAT. Já o plano 3D-CRT-FIF apresenta maior homogeneidade comparado ao 3D-CRT-FILTRO. Para o pulmão contralateral, os planos de 3D-CRT (FIF, FILTRO) obtiveram restrições melhores em relação aos demais planos. Sobre a exposição cardíaca, os planos 3D-CRT (FIF, FILTRO) apresentaram maiores benefícios do que as técnicas IMRT, VMAT e VMAT modificada. Conclusão: As técnicas convencionais 3D-CRT (FIF, FILTRO) apresentaram menores doses nos órgãos de risco. Contudo, as técnicas IMRT e VMAT obtiveram melhor homogeneidade e conformidade da dose distribuída no PTV ao comparar as técnicas convencionais.INCA2023-07-13info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfapplication/pdfapplication/pdftext/htmlhttps://rbc.inca.gov.br/index.php/revista/article/view/402010.32635/2176-9745.RBC.2023v69n3.4020Revista Brasileira de Cancerologia; Vol. 69 No. 3 (2023): July/Aug./Sept.; e-074020Revista Brasileira de Cancerologia; Vol. 69 Núm. 3 (2023): jul./ago./sept.; e-074020Revista Brasileira de Cancerologia; v. 69 n. 3 (2023): jul./ago./set.; e-0740202176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporengspahttps://rbc.inca.gov.br/index.php/revista/article/view/4020/3018https://rbc.inca.gov.br/index.php/revista/article/view/4020/3319https://rbc.inca.gov.br/index.php/revista/article/view/4020/3214https://rbc.inca.gov.br/index.php/revista/article/view/4020/3028Copyright (c) 2023 Revista Brasileira de Cancerologiahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPrandi, Tatiane Mayla DomingosZaias, Herofen Silva , Charlene daMüller , Juliana dos SantosBlasius, Larissa Palhano da Silva Dorow , Patrícia Fernanda2024-01-10T14:20:15Zoai:rbc.inca.gov.br:article/4020Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2024-01-10T14:20:15Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Dosimetry Comparison of Radiotherapy Planning Techniques for Left Breast Cancer
Comparación Dosimétrica entre Técnicas de Planificación de Radioterapia para el Cáncer de Mama Izquierdo
Comparação Dosimétrica entre Técnicas de Planejamento de Radioterapia para Câncer de Mama Esquerda
title Dosimetry Comparison of Radiotherapy Planning Techniques for Left Breast Cancer
spellingShingle Dosimetry Comparison of Radiotherapy Planning Techniques for Left Breast Cancer
Dosimetry Comparison of Radiotherapy Planning Techniques for Left Breast Cancer
Prandi, Tatiane Mayla Domingos
radioterapia conformacional
radioterapia de intensidade modulada
neoplasias da mama
doses de radiação
radiotherapy, conformal
radiotherapy, intensity-modulated
breast neoplasms
radiation dosage
radioterapia conformacional
radioterapia de intensidad modulada
neoplasias de la mama
dosis de radiación
Prandi, Tatiane Mayla Domingos
radioterapia conformacional
radioterapia de intensidade modulada
neoplasias da mama
doses de radiação
radiotherapy, conformal
radiotherapy, intensity-modulated
breast neoplasms
radiation dosage
radioterapia conformacional
radioterapia de intensidad modulada
neoplasias de la mama
dosis de radiación
title_short Dosimetry Comparison of Radiotherapy Planning Techniques for Left Breast Cancer
title_full Dosimetry Comparison of Radiotherapy Planning Techniques for Left Breast Cancer
title_fullStr Dosimetry Comparison of Radiotherapy Planning Techniques for Left Breast Cancer
Dosimetry Comparison of Radiotherapy Planning Techniques for Left Breast Cancer
title_full_unstemmed Dosimetry Comparison of Radiotherapy Planning Techniques for Left Breast Cancer
Dosimetry Comparison of Radiotherapy Planning Techniques for Left Breast Cancer
title_sort Dosimetry Comparison of Radiotherapy Planning Techniques for Left Breast Cancer
author Prandi, Tatiane Mayla Domingos
author_facet Prandi, Tatiane Mayla Domingos
Prandi, Tatiane Mayla Domingos
Zaias, Herofen
Silva , Charlene da
Müller , Juliana dos Santos
Blasius, Larissa Palhano da Silva
Dorow , Patrícia Fernanda
Zaias, Herofen
Silva , Charlene da
Müller , Juliana dos Santos
Blasius, Larissa Palhano da Silva
Dorow , Patrícia Fernanda
author_role author
author2 Zaias, Herofen
Silva , Charlene da
Müller , Juliana dos Santos
Blasius, Larissa Palhano da Silva
Dorow , Patrícia Fernanda
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Prandi, Tatiane Mayla Domingos
Zaias, Herofen
Silva , Charlene da
Müller , Juliana dos Santos
Blasius, Larissa Palhano da Silva
Dorow , Patrícia Fernanda
dc.subject.por.fl_str_mv radioterapia conformacional
radioterapia de intensidade modulada
neoplasias da mama
doses de radiação
radiotherapy, conformal
radiotherapy, intensity-modulated
breast neoplasms
radiation dosage
radioterapia conformacional
radioterapia de intensidad modulada
neoplasias de la mama
dosis de radiación
topic radioterapia conformacional
radioterapia de intensidade modulada
neoplasias da mama
doses de radiação
radiotherapy, conformal
radiotherapy, intensity-modulated
breast neoplasms
radiation dosage
radioterapia conformacional
radioterapia de intensidad modulada
neoplasias de la mama
dosis de radiación
description Introduction: Radiotherapy is utilized to treat breast cancer. For radiotherapy planning, there are several ways to develop the treatment plan, such as 3D conformal radiotherapy (3D-CRT), intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT). Objective: To compare the doses to risk organs and treatment target volume with different planning techniques, 3D-CRT, IMRT, VMAT and modified VMAT for the treatment of breast cancer in an anthropomorphic phantom. Method: The treatment plan was performed in the Eclipse™ v.15.6 system by Varian from CT images acquired from phantom. The established prescription dose was 45 Gy in 25 fractions of 1.8Gy/day. Results: For the planning target volume (PTV) coverage, 3D-CRT techniques (FILTER and field-in-field – FIF) showed inferior coverage compared to IMRT and VMAT plans. The 3D-CRT-FIF plan, on the other hand, shows greater homogeneity when compared to 3D-CRT-FILTER. For the contralateral lung, the 3D-CRT plans (FIF, FILTER) have better restrictions when compared with the other plans. On cardiac exposure, the 3D-CRT (FIF, FILTER) plans showed greater benefits when compared with IMRT, VMAT and Modified VMAT techniques. Conclusion: Conventional 3D-CRT techniques (FIF, FILTER) showed lower doses in organs at risk. However, IMRT and VMAT techniques obtained better homogeneity and conformity of the dose delivered to the PTV when compared to conventional techniques.
publishDate 2023
dc.date.none.fl_str_mv 2023-07-13
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/4020
10.32635/2176-9745.RBC.2023v69n3.4020
url https://rbc.inca.gov.br/index.php/revista/article/view/4020
identifier_str_mv 10.32635/2176-9745.RBC.2023v69n3.4020
dc.language.iso.fl_str_mv por
eng
spa
language por
eng
spa
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/4020/3018
https://rbc.inca.gov.br/index.php/revista/article/view/4020/3319
https://rbc.inca.gov.br/index.php/revista/article/view/4020/3214
https://rbc.inca.gov.br/index.php/revista/article/view/4020/3028
dc.rights.driver.fl_str_mv Copyright (c) 2023 Revista Brasileira de Cancerologia
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2023 Revista Brasileira de Cancerologia
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
text/html
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 69 No. 3 (2023): July/Aug./Sept.; e-074020
Revista Brasileira de Cancerologia; Vol. 69 Núm. 3 (2023): jul./ago./sept.; e-074020
Revista Brasileira de Cancerologia; v. 69 n. 3 (2023): jul./ago./set.; e-074020
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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dc.identifier.doi.none.fl_str_mv 10.32635/2176-9745.RBC.2023v69n3.4020

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