Cannabinoids, anxiety, and the periaqueductal gray

Detalhes bibliográficos
Autor(a) principal: Saito,Viviane M
Data de Publicação: 2010
Outros Autores: Moreira,Fabrício A
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Psychology & Neuroscience (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882010000100004
Resumo: The use of Cannabis sativa by humans dates back several thousand years, for both its psychotomimetic and potential medicinal properties. As scientific research methods developed, the cannabinoids present in this herb were characterized, as well as their complex interface with the human central nervous system, provided by the activation of specific receptors. The subsequent description of an endogenous cannabinoid system in the mammalian brain shifted the notion of cannabis as a recreational drug to a therapeutic alternative for psychiatric disorders. However, the neuroanatomical sites mediating its effects have remained uncertain. In the present paper, we review recent data suggesting that the midbrain periaqueductal gray may be a structure involved in the anxiolytic-like effects of cannabinoids.
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spelling Cannabinoids, anxiety, and the periaqueductal graycannabisendocannabinoidsanxietyperiaqueductal grayThe use of Cannabis sativa by humans dates back several thousand years, for both its psychotomimetic and potential medicinal properties. As scientific research methods developed, the cannabinoids present in this herb were characterized, as well as their complex interface with the human central nervous system, provided by the activation of specific receptors. The subsequent description of an endogenous cannabinoid system in the mammalian brain shifted the notion of cannabis as a recreational drug to a therapeutic alternative for psychiatric disorders. However, the neuroanatomical sites mediating its effects have remained uncertain. In the present paper, we review recent data suggesting that the midbrain periaqueductal gray may be a structure involved in the anxiolytic-like effects of cannabinoids.Pontificia Universidade Católica do Rio de JaneiroUniversidade de BrasíliaUniversidade de São Paulo2010-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882010000100004Psychology & Neuroscience v.3 n.1 2010reponame:Psychology & Neuroscience (Online)instname:Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)instacron:PUCRJ10.3922/j.psns.2010.1.004info:eu-repo/semantics/openAccessSaito,Viviane MMoreira,Fabrício Aeng2011-01-12T00:00:00Zoai:scielo:S1983-32882010000100004Revistahttps://www.apa.org/pubs/journals/pnePRIhttps://old.scielo.br/oai/scielo-oai.phppsycneuro@psycneuro.org1983-32881984-3054opendoar:2011-01-12T00:00Psychology & Neuroscience (Online) - Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)false
dc.title.none.fl_str_mv Cannabinoids, anxiety, and the periaqueductal gray
title Cannabinoids, anxiety, and the periaqueductal gray
spellingShingle Cannabinoids, anxiety, and the periaqueductal gray
Saito,Viviane M
cannabis
endocannabinoids
anxiety
periaqueductal gray
title_short Cannabinoids, anxiety, and the periaqueductal gray
title_full Cannabinoids, anxiety, and the periaqueductal gray
title_fullStr Cannabinoids, anxiety, and the periaqueductal gray
title_full_unstemmed Cannabinoids, anxiety, and the periaqueductal gray
title_sort Cannabinoids, anxiety, and the periaqueductal gray
author Saito,Viviane M
author_facet Saito,Viviane M
Moreira,Fabrício A
author_role author
author2 Moreira,Fabrício A
author2_role author
dc.contributor.author.fl_str_mv Saito,Viviane M
Moreira,Fabrício A
dc.subject.por.fl_str_mv cannabis
endocannabinoids
anxiety
periaqueductal gray
topic cannabis
endocannabinoids
anxiety
periaqueductal gray
description The use of Cannabis sativa by humans dates back several thousand years, for both its psychotomimetic and potential medicinal properties. As scientific research methods developed, the cannabinoids present in this herb were characterized, as well as their complex interface with the human central nervous system, provided by the activation of specific receptors. The subsequent description of an endogenous cannabinoid system in the mammalian brain shifted the notion of cannabis as a recreational drug to a therapeutic alternative for psychiatric disorders. However, the neuroanatomical sites mediating its effects have remained uncertain. In the present paper, we review recent data suggesting that the midbrain periaqueductal gray may be a structure involved in the anxiolytic-like effects of cannabinoids.
publishDate 2010
dc.date.none.fl_str_mv 2010-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882010000100004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882010000100004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.3922/j.psns.2010.1.004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Pontificia Universidade Católica do Rio de Janeiro
Universidade de Brasília
Universidade de São Paulo
publisher.none.fl_str_mv Pontificia Universidade Católica do Rio de Janeiro
Universidade de Brasília
Universidade de São Paulo
dc.source.none.fl_str_mv Psychology & Neuroscience v.3 n.1 2010
reponame:Psychology & Neuroscience (Online)
instname:Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)
instacron:PUCRJ
instname_str Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)
instacron_str PUCRJ
institution PUCRJ
reponame_str Psychology & Neuroscience (Online)
collection Psychology & Neuroscience (Online)
repository.name.fl_str_mv Psychology & Neuroscience (Online) - Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)
repository.mail.fl_str_mv psycneuro@psycneuro.org
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