Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats

Detalhes bibliográficos
Autor(a) principal: Veiga,Caroline Perinazzo da
Data de Publicação: 2011
Outros Autores: Aranda,Bruno Carlo Cerpa, Stein,Dirson, Franci,Celso Rodrigues, Miczek,Klaus A., Lucion,Aldo Bolten, Almeida,Rosa Maria Martins de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Psychology & Neuroscience (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882011000100012
Resumo: Among rodents, maternal aggression in the postpartum period represents a species-typical adaptation, but when aggressive behavior increases beyond this adaptive level, it can represent a model of excessive aggression. This study assessed the neuroendocrine response of lactating rats and socially instigated male rats. The aim of the present study was to assess neuroendocrine responses and the behavioral pattern of lactating rats and males that were subjected to an emotional stressor using the social instigation protocol. We measured plasma corticosterone levels as the key hormonal parameter of the hypothalamic-pituitary-adrenal (HPA) axis and oxytocin, prolactin, and progesterone, which are released in response to several types of stressors. Our results showed that lactating rats that were subjected to only social instigation or aggressive confrontation in the presence of their pups had lower plasma corticosterone levels, and this response was similar to oxytocin, prolactin, and progesterone levels. By contrast, male rats showed increased corticosterone levels after being subjected only to social instigation. Male rats also engaged in aggressive behavior compared with the control group. In conclusion, this study demonstrated that lactating rats subjected to social instigation exhibited an attenuation of the HPA axis response, which is considered to be crucial to the dam's welfare so that it can care for its offspring. Thus, we can infer that lactation is a relevant factor in neuroendocrine responses to stress because of the increased levels of corticosterone in males.
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spelling Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar ratssocial instigationlactating ratscorticosteronemaleHPA axisAmong rodents, maternal aggression in the postpartum period represents a species-typical adaptation, but when aggressive behavior increases beyond this adaptive level, it can represent a model of excessive aggression. This study assessed the neuroendocrine response of lactating rats and socially instigated male rats. The aim of the present study was to assess neuroendocrine responses and the behavioral pattern of lactating rats and males that were subjected to an emotional stressor using the social instigation protocol. We measured plasma corticosterone levels as the key hormonal parameter of the hypothalamic-pituitary-adrenal (HPA) axis and oxytocin, prolactin, and progesterone, which are released in response to several types of stressors. Our results showed that lactating rats that were subjected to only social instigation or aggressive confrontation in the presence of their pups had lower plasma corticosterone levels, and this response was similar to oxytocin, prolactin, and progesterone levels. By contrast, male rats showed increased corticosterone levels after being subjected only to social instigation. Male rats also engaged in aggressive behavior compared with the control group. In conclusion, this study demonstrated that lactating rats subjected to social instigation exhibited an attenuation of the HPA axis response, which is considered to be crucial to the dam's welfare so that it can care for its offspring. Thus, we can infer that lactation is a relevant factor in neuroendocrine responses to stress because of the increased levels of corticosterone in males.Pontificia Universidade Católica do Rio de JaneiroUniversidade de BrasíliaUniversidade de São Paulo2011-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882011000100012Psychology & Neuroscience v.4 n.1 2011reponame:Psychology & Neuroscience (Online)instname:Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)instacron:PUCRJ10.3922/j.psns.2011.1.012info:eu-repo/semantics/openAccessVeiga,Caroline Perinazzo daAranda,Bruno Carlo CerpaStein,DirsonFranci,Celso RodriguesMiczek,Klaus A.Lucion,Aldo BoltenAlmeida,Rosa Maria Martins deeng2011-08-23T00:00:00Zoai:scielo:S1983-32882011000100012Revistahttps://www.apa.org/pubs/journals/pnePRIhttps://old.scielo.br/oai/scielo-oai.phppsycneuro@psycneuro.org1983-32881984-3054opendoar:2011-08-23T00:00Psychology & Neuroscience (Online) - Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)false
dc.title.none.fl_str_mv Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
title Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
spellingShingle Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
Veiga,Caroline Perinazzo da
social instigation
lactating rats
corticosterone
male
HPA axis
title_short Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
title_full Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
title_fullStr Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
title_full_unstemmed Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
title_sort Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
author Veiga,Caroline Perinazzo da
author_facet Veiga,Caroline Perinazzo da
Aranda,Bruno Carlo Cerpa
Stein,Dirson
Franci,Celso Rodrigues
Miczek,Klaus A.
Lucion,Aldo Bolten
Almeida,Rosa Maria Martins de
author_role author
author2 Aranda,Bruno Carlo Cerpa
Stein,Dirson
Franci,Celso Rodrigues
Miczek,Klaus A.
Lucion,Aldo Bolten
Almeida,Rosa Maria Martins de
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Veiga,Caroline Perinazzo da
Aranda,Bruno Carlo Cerpa
Stein,Dirson
Franci,Celso Rodrigues
Miczek,Klaus A.
Lucion,Aldo Bolten
Almeida,Rosa Maria Martins de
dc.subject.por.fl_str_mv social instigation
lactating rats
corticosterone
male
HPA axis
topic social instigation
lactating rats
corticosterone
male
HPA axis
description Among rodents, maternal aggression in the postpartum period represents a species-typical adaptation, but when aggressive behavior increases beyond this adaptive level, it can represent a model of excessive aggression. This study assessed the neuroendocrine response of lactating rats and socially instigated male rats. The aim of the present study was to assess neuroendocrine responses and the behavioral pattern of lactating rats and males that were subjected to an emotional stressor using the social instigation protocol. We measured plasma corticosterone levels as the key hormonal parameter of the hypothalamic-pituitary-adrenal (HPA) axis and oxytocin, prolactin, and progesterone, which are released in response to several types of stressors. Our results showed that lactating rats that were subjected to only social instigation or aggressive confrontation in the presence of their pups had lower plasma corticosterone levels, and this response was similar to oxytocin, prolactin, and progesterone levels. By contrast, male rats showed increased corticosterone levels after being subjected only to social instigation. Male rats also engaged in aggressive behavior compared with the control group. In conclusion, this study demonstrated that lactating rats subjected to social instigation exhibited an attenuation of the HPA axis response, which is considered to be crucial to the dam's welfare so that it can care for its offspring. Thus, we can infer that lactation is a relevant factor in neuroendocrine responses to stress because of the increased levels of corticosterone in males.
publishDate 2011
dc.date.none.fl_str_mv 2011-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882011000100012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882011000100012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.3922/j.psns.2011.1.012
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Pontificia Universidade Católica do Rio de Janeiro
Universidade de Brasília
Universidade de São Paulo
publisher.none.fl_str_mv Pontificia Universidade Católica do Rio de Janeiro
Universidade de Brasília
Universidade de São Paulo
dc.source.none.fl_str_mv Psychology & Neuroscience v.4 n.1 2011
reponame:Psychology & Neuroscience (Online)
instname:Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)
instacron:PUCRJ
instname_str Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)
instacron_str PUCRJ
institution PUCRJ
reponame_str Psychology & Neuroscience (Online)
collection Psychology & Neuroscience (Online)
repository.name.fl_str_mv Psychology & Neuroscience (Online) - Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)
repository.mail.fl_str_mv psycneuro@psycneuro.org
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