Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats

Detalhes bibliográficos
Autor(a) principal: Veiga, Caroline Perinazzo da
Data de Publicação: 2011
Outros Autores: Aranda, Bruno Carlo Cerpa, Stein, Dirson João, Franci, Celso Rodrigues, Miczek, Klaus Alexander, Lucion, Aldo Bolten, Almeida, Rosa Maria Martins de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/108547
Resumo: Among rodents, maternal aggression in the postpartum period represents a species-typical adaptation, but when aggressive behavior increases beyond this adaptive level, it can represent a model of excessive aggression. This study assessed the neuroendocrine response of lactating rats and socially instigated male rats. The aim of the present study was to assess neuroendocrine responses and the behavioral pattern of lactating rats and males that were subjected to an emotional stressor using the social instigation protocol. We measured plasma corticosterone levels as the key hormonal parameter of the hypothalamic-pituitary-adrenal (HPA) axis and oxytocin, prolactin, and progesterone, which are released in response to several types of stressors. Our results showed that lactating rats that were subjected to only social instigation or aggressive confrontation in the presence of their pups had lower plasma corticosterone levels, and this response was similar to oxytocin, prolactin, and progesterone levels. By contrast, male rats showed increased corticosterone levels after being subjected only to social instigation. Male rats also engaged in aggressive behavior compared with the control group. In conclusion, this study demonstrated that lactating rats subjected to social instigation exhibited an attenuation of the HPA axis response, which is considered to be crucial to the dam’s welfare so that it can care for its offspring. Thus, we can infer that lactation is a relevant factor in neuroendocrine responses to stress because of the increased levels of corticosterone in males.
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spelling Veiga, Caroline Perinazzo daAranda, Bruno Carlo CerpaStein, Dirson JoãoFranci, Celso RodriguesMiczek, Klaus AlexanderLucion, Aldo BoltenAlmeida, Rosa Maria Martins de2014-12-23T02:13:28Z20111983-3288http://hdl.handle.net/10183/108547000790007Among rodents, maternal aggression in the postpartum period represents a species-typical adaptation, but when aggressive behavior increases beyond this adaptive level, it can represent a model of excessive aggression. This study assessed the neuroendocrine response of lactating rats and socially instigated male rats. The aim of the present study was to assess neuroendocrine responses and the behavioral pattern of lactating rats and males that were subjected to an emotional stressor using the social instigation protocol. We measured plasma corticosterone levels as the key hormonal parameter of the hypothalamic-pituitary-adrenal (HPA) axis and oxytocin, prolactin, and progesterone, which are released in response to several types of stressors. Our results showed that lactating rats that were subjected to only social instigation or aggressive confrontation in the presence of their pups had lower plasma corticosterone levels, and this response was similar to oxytocin, prolactin, and progesterone levels. By contrast, male rats showed increased corticosterone levels after being subjected only to social instigation. Male rats also engaged in aggressive behavior compared with the control group. In conclusion, this study demonstrated that lactating rats subjected to social instigation exhibited an attenuation of the HPA axis response, which is considered to be crucial to the dam’s welfare so that it can care for its offspring. Thus, we can infer that lactation is a relevant factor in neuroendocrine responses to stress because of the increased levels of corticosterone in males.application/pdfengPsychology & neuroscience. Rio de Janeiro, RJ. Vol. 4, n.1 (jan./jun. 2011), 103-113.Psicologia experimentalRatosEstresseLactaçãoComportamento animalCorticosteronaSocial instigationLactating ratsCorticosteroneMaleHPA axisEffect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar ratsinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000790007.pdf000790007.pdfTexto completo (inglês)application/pdf770443http://www.lume.ufrgs.br/bitstream/10183/108547/1/000790007.pdf85cc64c66d24162b344f3a99300ffa57MD51TEXT000790007.pdf.txt000790007.pdf.txtExtracted Texttext/plain57441http://www.lume.ufrgs.br/bitstream/10183/108547/2/000790007.pdf.txt9b809abf8ddab0e141b107f4210c3fa9MD52THUMBNAIL000790007.pdf.jpg000790007.pdf.jpgGenerated Thumbnailimage/jpeg2216http://www.lume.ufrgs.br/bitstream/10183/108547/3/000790007.pdf.jpg7e953c78cd5f641101b72181b90d616fMD5310183/1085472019-11-09 04:49:54.171841oai:www.lume.ufrgs.br:10183/108547Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2019-11-09T06:49:54Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
title Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
spellingShingle Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
Veiga, Caroline Perinazzo da
Psicologia experimental
Ratos
Estresse
Lactação
Comportamento animal
Corticosterona
Social instigation
Lactating rats
Corticosterone
Male
HPA axis
title_short Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
title_full Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
title_fullStr Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
title_full_unstemmed Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
title_sort Effect of social instigation and aggressive behavior on hormone levels of lactating dams and adult male Wistar rats
author Veiga, Caroline Perinazzo da
author_facet Veiga, Caroline Perinazzo da
Aranda, Bruno Carlo Cerpa
Stein, Dirson João
Franci, Celso Rodrigues
Miczek, Klaus Alexander
Lucion, Aldo Bolten
Almeida, Rosa Maria Martins de
author_role author
author2 Aranda, Bruno Carlo Cerpa
Stein, Dirson João
Franci, Celso Rodrigues
Miczek, Klaus Alexander
Lucion, Aldo Bolten
Almeida, Rosa Maria Martins de
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Veiga, Caroline Perinazzo da
Aranda, Bruno Carlo Cerpa
Stein, Dirson João
Franci, Celso Rodrigues
Miczek, Klaus Alexander
Lucion, Aldo Bolten
Almeida, Rosa Maria Martins de
dc.subject.por.fl_str_mv Psicologia experimental
Ratos
Estresse
Lactação
Comportamento animal
Corticosterona
topic Psicologia experimental
Ratos
Estresse
Lactação
Comportamento animal
Corticosterona
Social instigation
Lactating rats
Corticosterone
Male
HPA axis
dc.subject.eng.fl_str_mv Social instigation
Lactating rats
Corticosterone
Male
HPA axis
description Among rodents, maternal aggression in the postpartum period represents a species-typical adaptation, but when aggressive behavior increases beyond this adaptive level, it can represent a model of excessive aggression. This study assessed the neuroendocrine response of lactating rats and socially instigated male rats. The aim of the present study was to assess neuroendocrine responses and the behavioral pattern of lactating rats and males that were subjected to an emotional stressor using the social instigation protocol. We measured plasma corticosterone levels as the key hormonal parameter of the hypothalamic-pituitary-adrenal (HPA) axis and oxytocin, prolactin, and progesterone, which are released in response to several types of stressors. Our results showed that lactating rats that were subjected to only social instigation or aggressive confrontation in the presence of their pups had lower plasma corticosterone levels, and this response was similar to oxytocin, prolactin, and progesterone levels. By contrast, male rats showed increased corticosterone levels after being subjected only to social instigation. Male rats also engaged in aggressive behavior compared with the control group. In conclusion, this study demonstrated that lactating rats subjected to social instigation exhibited an attenuation of the HPA axis response, which is considered to be crucial to the dam’s welfare so that it can care for its offspring. Thus, we can infer that lactation is a relevant factor in neuroendocrine responses to stress because of the increased levels of corticosterone in males.
publishDate 2011
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dc.relation.ispartof.pt_BR.fl_str_mv Psychology & neuroscience. Rio de Janeiro, RJ. Vol. 4, n.1 (jan./jun. 2011), 103-113.
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