Calcium and caffeine interaction in increased calcium balance in ovariectomized rats
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2023 |
| Outros Autores: | , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Revista de Nutrição |
| Texto Completo: | https://periodicos.puc-campinas.edu.br/nutricao/article/view/8428 |
Resumo: | ObjectiveThis study investigated the effects of caffeine intake associated with inadequate or adequate calcium intake in laparotomized or ovariectomized rats by means of the calcium balance. Forty adults Wistar rats were ovariectomized or laparotomized. MethodsThe animals (n=40) were randomly placed in eight groups receiving the AIN-93 diet with 100% or 50% of the recommended calcium intake with or without added caffeine (6mg/kg/day). The animals were kept in individuals metabolic cages at a temperature of 24°±2o C, light/dark cycles of 12/12 hours, and deionized water available ad libitum. On the 8th week of the experiment, food consumption was measured and 24-hour urine and 4-day feces were collected to determine calcium balance [Balance=Ca intake-(Urinary Ca+Fecal Ca)]. ResultsAnimals with adequate calcium intake presented higher balances and rates of calcium absorption and retention (p<0.05) than those with inadequate calcium intake, regardless of caffeine intake (p<0.05). Caffeine intake did not affect urinary calcium excretion but increased balance (p<0.05) in the groups with adequate calcium intake. ConclusionAdequate calcium intake attenuated the negative effects of estrogen deficiency and improved calcium balance even in the presence of caffeine. |
| id |
PUC_CAMP-2_f3d1130d4d8d7b67a96b47efed9fb8e2 |
|---|---|
| oai_identifier_str |
oai:ojs.periodicos.puc-campinas.edu.br:article/8428 |
| network_acronym_str |
PUC_CAMP-2 |
| network_name_str |
Revista de Nutrição |
| repository_id_str |
|
| spelling |
Calcium and caffeine interaction in increased calcium balance in ovariectomized ratsInteração cálcio e cafeína no aumento do balanço de cálcio em ratas ovariectomizadasCaffeineCalcium bioavailabilityEstrogenCafeínaBiodisponibilidade do cálcioEstrogênioObjectiveThis study investigated the effects of caffeine intake associated with inadequate or adequate calcium intake in laparotomized or ovariectomized rats by means of the calcium balance. Forty adults Wistar rats were ovariectomized or laparotomized. MethodsThe animals (n=40) were randomly placed in eight groups receiving the AIN-93 diet with 100% or 50% of the recommended calcium intake with or without added caffeine (6mg/kg/day). The animals were kept in individuals metabolic cages at a temperature of 24°±2o C, light/dark cycles of 12/12 hours, and deionized water available ad libitum. On the 8th week of the experiment, food consumption was measured and 24-hour urine and 4-day feces were collected to determine calcium balance [Balance=Ca intake-(Urinary Ca+Fecal Ca)]. ResultsAnimals with adequate calcium intake presented higher balances and rates of calcium absorption and retention (p<0.05) than those with inadequate calcium intake, regardless of caffeine intake (p<0.05). Caffeine intake did not affect urinary calcium excretion but increased balance (p<0.05) in the groups with adequate calcium intake. ConclusionAdequate calcium intake attenuated the negative effects of estrogen deficiency and improved calcium balance even in the presence of caffeine. ObjetivoInvestigar a relação entre a ingestão de cafeína e a adequação de cálcio dietético em ratas ovariectomizadas ou inteiras, por meio do balanço de cálcio. Foram utilizadas 40 ratas Wistar adultas submetidas à cirurgia de ovariectomia ou laparotomia. MétodosOs animais foram alocados em grupos (n=5) e receberam dieta AIN-93M contendo 100 ou 50% da recomendação de cálcio com ou sem adição de cafeína (6mg/kg/dia). As fêmeas foram alojadas em gaiolas metabólicas individuais, à temperatura de 24±2oC e ciclo de 12 horas claro/escuro e receberam água deionizada ad libitum. Na oitava semana de experimento, quantificou-se a ingestão da dieta e coletaram-se fezes de 4 dias e urina dos animais por 24 horas para determinação do balanço [Balanço=Ca Ingerido - (Ca Fecal+Ca Urinário)]. ResultadosPor meio de interação entre fatores, foi observado que o consumo de 100% de cálcio elevou o balanço e os teores de cálcio absorvido e retido (p<0,05) quando comparados aos grupos 50%. As ratas com adequação no consumo de cálcio aumentaram o balanço (p<0,05), independentemente da suplementação de cafeína. A ingestão de cafeína não afetou a excreção urinária de cálcio e elevou (p<0,05) o balanço nas ratas com 100% de cálcio, mas não nas com 50%. ConclusãoA adequação no consumo de cálcio atenuou os efeitos deletérios da redução estrogênica e proporcionou maior balanço de cálcio mesmo com ingestão de cafeína. Núcleo de Editoração – PUC-Campinas2023-04-20info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.puc-campinas.edu.br/nutricao/article/view/8428Brazilian Journal of Nutrition; Vol. 26 No. 3 (2013): Revista de NutriçãoRevista de Nutrição; Vol. 26 Núm. 3 (2013): Revista de NutriçãoRevista de Nutrição; v. 26 n. 3 (2013): Revista de Nutrição1678-9865reponame:Revista de Nutriçãoinstname:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)instacron:PUC_CAMPenghttps://periodicos.puc-campinas.edu.br/nutricao/article/view/8428/5937Copyright (c) 2023 Sandra Tavares da SILVA, Neuza Maria Brunoro COSTA, Frederico Souza Lima Caldoncelli FRANCO, Antônio José NATALIhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessTavares da SILVA, Sandra Brunoro COSTA, Neuza Maria Souza Lima Caldoncelli FRANCO, Frederico NATALI, Antônio José2023-10-05T19:19:30Zoai:ojs.periodicos.puc-campinas.edu.br:article/8428Revistahttp://www.scielo.br/rnPRIhttps://periodicos.puc-campinas.edu.br/nutricao/oai||sbi.submissionrn@puc-campinas.edu.br1678-98651415-5273opendoar:2023-10-05T19:19:30Revista de Nutrição - Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)false |
| dc.title.none.fl_str_mv |
Calcium and caffeine interaction in increased calcium balance in ovariectomized rats Interação cálcio e cafeína no aumento do balanço de cálcio em ratas ovariectomizadas |
| title |
Calcium and caffeine interaction in increased calcium balance in ovariectomized rats |
| spellingShingle |
Calcium and caffeine interaction in increased calcium balance in ovariectomized rats Tavares da SILVA, Sandra Caffeine Calcium bioavailability Estrogen Cafeína Biodisponibilidade do cálcio Estrogênio |
| title_short |
Calcium and caffeine interaction in increased calcium balance in ovariectomized rats |
| title_full |
Calcium and caffeine interaction in increased calcium balance in ovariectomized rats |
| title_fullStr |
Calcium and caffeine interaction in increased calcium balance in ovariectomized rats |
| title_full_unstemmed |
Calcium and caffeine interaction in increased calcium balance in ovariectomized rats |
| title_sort |
Calcium and caffeine interaction in increased calcium balance in ovariectomized rats |
| author |
Tavares da SILVA, Sandra |
| author_facet |
Tavares da SILVA, Sandra Brunoro COSTA, Neuza Maria Souza Lima Caldoncelli FRANCO, Frederico NATALI, Antônio José |
| author_role |
author |
| author2 |
Brunoro COSTA, Neuza Maria Souza Lima Caldoncelli FRANCO, Frederico NATALI, Antônio José |
| author2_role |
author author author |
| dc.contributor.author.fl_str_mv |
Tavares da SILVA, Sandra Brunoro COSTA, Neuza Maria Souza Lima Caldoncelli FRANCO, Frederico NATALI, Antônio José |
| dc.subject.por.fl_str_mv |
Caffeine Calcium bioavailability Estrogen Cafeína Biodisponibilidade do cálcio Estrogênio |
| topic |
Caffeine Calcium bioavailability Estrogen Cafeína Biodisponibilidade do cálcio Estrogênio |
| description |
ObjectiveThis study investigated the effects of caffeine intake associated with inadequate or adequate calcium intake in laparotomized or ovariectomized rats by means of the calcium balance. Forty adults Wistar rats were ovariectomized or laparotomized. MethodsThe animals (n=40) were randomly placed in eight groups receiving the AIN-93 diet with 100% or 50% of the recommended calcium intake with or without added caffeine (6mg/kg/day). The animals were kept in individuals metabolic cages at a temperature of 24°±2o C, light/dark cycles of 12/12 hours, and deionized water available ad libitum. On the 8th week of the experiment, food consumption was measured and 24-hour urine and 4-day feces were collected to determine calcium balance [Balance=Ca intake-(Urinary Ca+Fecal Ca)]. ResultsAnimals with adequate calcium intake presented higher balances and rates of calcium absorption and retention (p<0.05) than those with inadequate calcium intake, regardless of caffeine intake (p<0.05). Caffeine intake did not affect urinary calcium excretion but increased balance (p<0.05) in the groups with adequate calcium intake. ConclusionAdequate calcium intake attenuated the negative effects of estrogen deficiency and improved calcium balance even in the presence of caffeine. |
| publishDate |
2023 |
| dc.date.none.fl_str_mv |
2023-04-20 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://periodicos.puc-campinas.edu.br/nutricao/article/view/8428 |
| url |
https://periodicos.puc-campinas.edu.br/nutricao/article/view/8428 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
https://periodicos.puc-campinas.edu.br/nutricao/article/view/8428/5937 |
| dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Núcleo de Editoração – PUC-Campinas |
| publisher.none.fl_str_mv |
Núcleo de Editoração – PUC-Campinas |
| dc.source.none.fl_str_mv |
Brazilian Journal of Nutrition; Vol. 26 No. 3 (2013): Revista de Nutrição Revista de Nutrição; Vol. 26 Núm. 3 (2013): Revista de Nutrição Revista de Nutrição; v. 26 n. 3 (2013): Revista de Nutrição 1678-9865 reponame:Revista de Nutrição instname:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS) instacron:PUC_CAMP |
| instname_str |
Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS) |
| instacron_str |
PUC_CAMP |
| institution |
PUC_CAMP |
| reponame_str |
Revista de Nutrição |
| collection |
Revista de Nutrição |
| repository.name.fl_str_mv |
Revista de Nutrição - Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS) |
| repository.mail.fl_str_mv |
||sbi.submissionrn@puc-campinas.edu.br |
| _version_ |
1799126070160523264 |