Cortisol levels in patients presenting generalized chronic periodontitis and diabetes mellitus

Detalhes bibliográficos
Autor(a) principal: Arantes, Júlio César
Data de Publicação: 2008
Outros Autores: Eustáquio, Igor, Stefani, Cristine Miron, Motão, José Claudio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista odonto ciência (Online)
Texto Completo: https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/3869
Resumo: Purpose: This study evaluated cortisol levels in healthy subjects, patients with generalized chronic periodontitis (GCP) and diabetes mellitus (DM) type 2, and patients with GCP without DM. Methods: Fifty-nine subjects were selected and categorized into: 1) Control group (n=19, age: 36.4±5.1 years old), 2) Case 1 group (n=11, age: 54.2±19.6 years old) comprising subjects with GCP and DM type 2, and 3) Case 2 group (n=29, age: 40.9±4.4 years old) comprising subjects with GCP. The clinical parameters assessed were: gingival index (GI), probing pocket depth (PPD), probing attachment level (PAL), cortisol levels in plasma, and blood glucose. Results: The clinical parameters PPD and PAL and cortisol levels were statistically different (P=0.01) between the control group and groups Case 1 and Case 2. There was no significant difference between Case 1 and Case 2 groups. Conclusion: Subjects with GCP and DM type 2 showed significant higher cortisol levels than healthy subjects. However, the presence of diabetes did not worsen periodontal disease. Key words: Cortisol; periodontal disease; diabetes mellitus
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spelling Cortisol levels in patients presenting generalized chronic periodontitis and diabetes mellitusNível de cortisol em pacientes com periodontite crônica generalizada e diabetes mellitusCortisolperiodontal diseasediabetes mellitusPathogenesis of the periodontal diseasePurpose: This study evaluated cortisol levels in healthy subjects, patients with generalized chronic periodontitis (GCP) and diabetes mellitus (DM) type 2, and patients with GCP without DM. Methods: Fifty-nine subjects were selected and categorized into: 1) Control group (n=19, age: 36.4±5.1 years old), 2) Case 1 group (n=11, age: 54.2±19.6 years old) comprising subjects with GCP and DM type 2, and 3) Case 2 group (n=29, age: 40.9±4.4 years old) comprising subjects with GCP. The clinical parameters assessed were: gingival index (GI), probing pocket depth (PPD), probing attachment level (PAL), cortisol levels in plasma, and blood glucose. Results: The clinical parameters PPD and PAL and cortisol levels were statistically different (P=0.01) between the control group and groups Case 1 and Case 2. There was no significant difference between Case 1 and Case 2 groups. Conclusion: Subjects with GCP and DM type 2 showed significant higher cortisol levels than healthy subjects. However, the presence of diabetes did not worsen periodontal disease. Key words: Cortisol; periodontal disease; diabetes mellitusObjetivo: Este trabalho avaliou o nível de cortisol sangüíneo em sujeitos saudáveis, sujeitos com periodontite crônica generalizada (PCG) apresentando diabetes mellitus (DM) tipo 2 e sujeitos com PCG e sem DM. Metodologia: Foram selecionados 59 pacientes de ambos os gêneros, sendo um grupo Controle saudável (n=19, idade média de 36,4±5,1 anos), um grupo Caso 1 apresentando PCG e DM tipo 2 (n=11, idade média de 54,2±19,6 anos) e outro grupo Caso 2 apresentando PCG (n=29, idade média de 40,9±4,4 anos). Os parâmetros clínicos observados foram: profundidade de bolsa à sondagem (PBS), nível de inserção clínica (NIC), taxa de cortisol sangüíneo e glicemia. Resultados: Os parâmetros clínicos PBS e NIC e a taxa de cortisol sangüíneo apresentaram diferenças estatísticas significantes (P=0,01) entre o grupo controle e os grupos Caso 1 e Caso 2, mas não houve diferença significante entre os grupos Caso 1 e Caso 2. Conclusão: Pacientes apresentando PCG e com DM tipo 2 não compensada têm aumento significativo no nível de cortisol em comparação a pacientes saudáveis. No entanto, a presença de DM tipo 2 não agravou a doença periodontal. Palavras-chave: Cortisol; periodontite; diabetes mellitusEDIPUCRS - Editora Universitária da PUCRS2008-10-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed Articlecase-control studyapplication/pdfhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/3869Revista Odonto Ciência; Vol. 23 No. 4 (2008); 384 - 387Revista Odonto Ciência; v. 23 n. 4 (2008); 384 - 3871980-65230102-9460reponame:Revista odonto ciência (Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSenghttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/3869/3441Arantes, Júlio CésarEustáquio, IgorStefani, Cristine MironMotão, José Claudioinfo:eu-repo/semantics/openAccess2013-11-18T10:32:04Zoai:ojs.revistaseletronicas.pucrs.br:article/3869Revistahttps://revistaseletronicas.pucrs.br/ojs/index.php/foPRIhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/oai||odontociencia@pucrs.br1980-65230102-9460opendoar:2013-11-18T10:32:04Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.none.fl_str_mv Cortisol levels in patients presenting generalized chronic periodontitis and diabetes mellitus
Nível de cortisol em pacientes com periodontite crônica generalizada e diabetes mellitus
title Cortisol levels in patients presenting generalized chronic periodontitis and diabetes mellitus
spellingShingle Cortisol levels in patients presenting generalized chronic periodontitis and diabetes mellitus
Arantes, Júlio César
Cortisol
periodontal disease
diabetes mellitus
Pathogenesis of the periodontal disease
title_short Cortisol levels in patients presenting generalized chronic periodontitis and diabetes mellitus
title_full Cortisol levels in patients presenting generalized chronic periodontitis and diabetes mellitus
title_fullStr Cortisol levels in patients presenting generalized chronic periodontitis and diabetes mellitus
title_full_unstemmed Cortisol levels in patients presenting generalized chronic periodontitis and diabetes mellitus
title_sort Cortisol levels in patients presenting generalized chronic periodontitis and diabetes mellitus
author Arantes, Júlio César
author_facet Arantes, Júlio César
Eustáquio, Igor
Stefani, Cristine Miron
Motão, José Claudio
author_role author
author2 Eustáquio, Igor
Stefani, Cristine Miron
Motão, José Claudio
author2_role author
author
author
dc.contributor.author.fl_str_mv Arantes, Júlio César
Eustáquio, Igor
Stefani, Cristine Miron
Motão, José Claudio
dc.subject.por.fl_str_mv Cortisol
periodontal disease
diabetes mellitus
Pathogenesis of the periodontal disease
topic Cortisol
periodontal disease
diabetes mellitus
Pathogenesis of the periodontal disease
description Purpose: This study evaluated cortisol levels in healthy subjects, patients with generalized chronic periodontitis (GCP) and diabetes mellitus (DM) type 2, and patients with GCP without DM. Methods: Fifty-nine subjects were selected and categorized into: 1) Control group (n=19, age: 36.4±5.1 years old), 2) Case 1 group (n=11, age: 54.2±19.6 years old) comprising subjects with GCP and DM type 2, and 3) Case 2 group (n=29, age: 40.9±4.4 years old) comprising subjects with GCP. The clinical parameters assessed were: gingival index (GI), probing pocket depth (PPD), probing attachment level (PAL), cortisol levels in plasma, and blood glucose. Results: The clinical parameters PPD and PAL and cortisol levels were statistically different (P=0.01) between the control group and groups Case 1 and Case 2. There was no significant difference between Case 1 and Case 2 groups. Conclusion: Subjects with GCP and DM type 2 showed significant higher cortisol levels than healthy subjects. However, the presence of diabetes did not worsen periodontal disease. Key words: Cortisol; periodontal disease; diabetes mellitus
publishDate 2008
dc.date.none.fl_str_mv 2008-10-14
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
case-control study
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/3869
url https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/3869
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/3869/3441
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv EDIPUCRS - Editora Universitária da PUCRS
publisher.none.fl_str_mv EDIPUCRS - Editora Universitária da PUCRS
dc.source.none.fl_str_mv Revista Odonto Ciência; Vol. 23 No. 4 (2008); 384 - 387
Revista Odonto Ciência; v. 23 n. 4 (2008); 384 - 387
1980-6523
0102-9460
reponame:Revista odonto ciência (Online)
instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
instname_str Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron_str PUC_RS
institution PUC_RS
reponame_str Revista odonto ciência (Online)
collection Revista odonto ciência (Online)
repository.name.fl_str_mv Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
repository.mail.fl_str_mv ||odontociencia@pucrs.br
_version_ 1754820874355081216

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