Effect of non-surgical periodontal therapy on the levels of C- reactive protein: a pilot study

Detalhes bibliográficos
Autor(a) principal: Freitas, Camila Oliveira Teixeira de
Data de Publicação: 2010
Outros Autores: Gomes-Filho, Isaac Suzart, Naves, Roberta Catapano, Cruz, Simone Seixas da, Santos, Carlos Antônio de Souza Teles, Barbosa, Monica Dourado da Silva
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista odonto ciência (Online)
Texto Completo: https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6227
Resumo: Purpose: C-reactive protein (CRP) is a marker of inflammation that is naturally present in the plasma at levels that may rise due to inflammatory processes, associated with a greater risk of cardiovascular events such as acute myocardial infarction. Periodontal disease is responsible for a host immune-inflammatory response, contributing towards clarifying its association with cardiovascular disease. The aim of this study was to investigate the effect of periodontal therapy on the levels of this inflammatory marker. Methods: The sample consisted of 62 patients of both genders, between the ages of 30 to 60 years, who were referred to dental treatment at the Bahia Foundation for the Development of Sciences, and they were divided into two groups: with and without periodontitis. The clinical descriptors used were the bleeding index, gingival recession, probing depth and clinical attachment level. For CRP analysis, peripheral blood was collected from these individuals and sent to a single clinical analysis laboratory. Results: The group with periodontitis was treated and the results showed that there was a statistically significant difference between the CRP levels before and after periodontal treatment (P < 0.05). Conclusion: From the final findings, it may be concluded that non-surgical periodontal therapy showed a tendency to reduce the CRP serum levels.
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spelling Effect of non-surgical periodontal therapy on the levels of C- reactive protein: a pilot studyEfeito da terapia periodontal não-cirúrgica nos níveis séricos de proteína C-reativa: estudo pilotoPeriodontal diseaseC-reactive proteinCardiovascular diseasePeriodontal diseaseDoença Periodontalproteína c-reativadoença cardiovascularDoença periodontalPurpose: C-reactive protein (CRP) is a marker of inflammation that is naturally present in the plasma at levels that may rise due to inflammatory processes, associated with a greater risk of cardiovascular events such as acute myocardial infarction. Periodontal disease is responsible for a host immune-inflammatory response, contributing towards clarifying its association with cardiovascular disease. The aim of this study was to investigate the effect of periodontal therapy on the levels of this inflammatory marker. Methods: The sample consisted of 62 patients of both genders, between the ages of 30 to 60 years, who were referred to dental treatment at the Bahia Foundation for the Development of Sciences, and they were divided into two groups: with and without periodontitis. The clinical descriptors used were the bleeding index, gingival recession, probing depth and clinical attachment level. For CRP analysis, peripheral blood was collected from these individuals and sent to a single clinical analysis laboratory. Results: The group with periodontitis was treated and the results showed that there was a statistically significant difference between the CRP levels before and after periodontal treatment (P < 0.05). Conclusion: From the final findings, it may be concluded that non-surgical periodontal therapy showed a tendency to reduce the CRP serum levels.Objetivo: Proteína C-Reativa (PCR) é um marcador de inflamação presente no plasma cujos níveis podem se elevar devido a um processo inflamatório, ocasionando um maior risco a eventos cardiovasculares, como o Infarto Agudo do Miocárdio. A doença periodontal promove uma resposta imuno-inflamatória do hospedeiro, contribuindo com níveis mais elevados de PCR, esclarecendo sua associação com a doença cardiovascular. Objetivou-se neste estudo verificar o efeito da terapia periodontal nos níveis desse marcador inflamatório. Metodologia: A amostra constou de 62 pacientes, de ambos os sexos, com faixa etária entre 30 e 60 anos, encaminhados para tratamento odontológico na Fundação Bahiana para Desenvolvimento das Ciências, e distribuídos entre dois grupos: com e sem periodontite. Os descritores clínicos empregados consistiram de Índice de Sangramento, Recessão Gengival, Profundidade de Sondagem e Nível de Inserção Clínica. Para a análise da PCR foi coletado sangue periférico dos indivíduos e encaminhados a um mesmo laboratório de análises clínicas. Resultados: O grupo com periodontite foi tratado e os resultados mostraram que houve diferença estatisticamente significante entre os níveis de PCR antes e após o tratamento periodontal (P < 0,05). Conclusão: De acordo com os achados finais, pode-se concluir que a terapia periodontal não cirúrgica apresentou uma tendência de redução dos níveis séricos da PCR.EDIPUCRS - Editora Universitária da PUCRS2010-11-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed Articlecase-controlcaso-controleapplication/pdfhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6227Revista Odonto Ciência; Vol. 26 No. 1 (2011); 16 - 21Revista Odonto Ciência; v. 26 n. 1 (2011); 16 - 211980-65230102-9460reponame:Revista odonto ciência (Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSenghttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6227/6211Freitas, Camila Oliveira Teixeira deGomes-Filho, Isaac SuzartNaves, Roberta CatapanoCruz, Simone Seixas daSantos, Carlos Antônio de Souza TelesBarbosa, Monica Dourado da Silvainfo:eu-repo/semantics/openAccess2013-11-11T12:11:57Zoai:ojs.revistaseletronicas.pucrs.br:article/6227Revistahttps://revistaseletronicas.pucrs.br/ojs/index.php/foPRIhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/oai||odontociencia@pucrs.br1980-65230102-9460opendoar:2013-11-11T12:11:57Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.none.fl_str_mv Effect of non-surgical periodontal therapy on the levels of C- reactive protein: a pilot study
Efeito da terapia periodontal não-cirúrgica nos níveis séricos de proteína C-reativa: estudo piloto
title Effect of non-surgical periodontal therapy on the levels of C- reactive protein: a pilot study
spellingShingle Effect of non-surgical periodontal therapy on the levels of C- reactive protein: a pilot study
Freitas, Camila Oliveira Teixeira de
Periodontal disease
C-reactive protein
Cardiovascular disease
Periodontal disease
Doença Periodontal
proteína c-reativa
doença cardiovascular
Doença periodontal
title_short Effect of non-surgical periodontal therapy on the levels of C- reactive protein: a pilot study
title_full Effect of non-surgical periodontal therapy on the levels of C- reactive protein: a pilot study
title_fullStr Effect of non-surgical periodontal therapy on the levels of C- reactive protein: a pilot study
title_full_unstemmed Effect of non-surgical periodontal therapy on the levels of C- reactive protein: a pilot study
title_sort Effect of non-surgical periodontal therapy on the levels of C- reactive protein: a pilot study
author Freitas, Camila Oliveira Teixeira de
author_facet Freitas, Camila Oliveira Teixeira de
Gomes-Filho, Isaac Suzart
Naves, Roberta Catapano
Cruz, Simone Seixas da
Santos, Carlos Antônio de Souza Teles
Barbosa, Monica Dourado da Silva
author_role author
author2 Gomes-Filho, Isaac Suzart
Naves, Roberta Catapano
Cruz, Simone Seixas da
Santos, Carlos Antônio de Souza Teles
Barbosa, Monica Dourado da Silva
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Freitas, Camila Oliveira Teixeira de
Gomes-Filho, Isaac Suzart
Naves, Roberta Catapano
Cruz, Simone Seixas da
Santos, Carlos Antônio de Souza Teles
Barbosa, Monica Dourado da Silva
dc.subject.por.fl_str_mv Periodontal disease
C-reactive protein
Cardiovascular disease
Periodontal disease
Doença Periodontal
proteína c-reativa
doença cardiovascular
Doença periodontal
topic Periodontal disease
C-reactive protein
Cardiovascular disease
Periodontal disease
Doença Periodontal
proteína c-reativa
doença cardiovascular
Doença periodontal
description Purpose: C-reactive protein (CRP) is a marker of inflammation that is naturally present in the plasma at levels that may rise due to inflammatory processes, associated with a greater risk of cardiovascular events such as acute myocardial infarction. Periodontal disease is responsible for a host immune-inflammatory response, contributing towards clarifying its association with cardiovascular disease. The aim of this study was to investigate the effect of periodontal therapy on the levels of this inflammatory marker. Methods: The sample consisted of 62 patients of both genders, between the ages of 30 to 60 years, who were referred to dental treatment at the Bahia Foundation for the Development of Sciences, and they were divided into two groups: with and without periodontitis. The clinical descriptors used were the bleeding index, gingival recession, probing depth and clinical attachment level. For CRP analysis, peripheral blood was collected from these individuals and sent to a single clinical analysis laboratory. Results: The group with periodontitis was treated and the results showed that there was a statistically significant difference between the CRP levels before and after periodontal treatment (P < 0.05). Conclusion: From the final findings, it may be concluded that non-surgical periodontal therapy showed a tendency to reduce the CRP serum levels.
publishDate 2010
dc.date.none.fl_str_mv 2010-11-29
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
case-control
caso-controle
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6227
url https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6227
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6227/6211
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv EDIPUCRS - Editora Universitária da PUCRS
publisher.none.fl_str_mv EDIPUCRS - Editora Universitária da PUCRS
dc.source.none.fl_str_mv Revista Odonto Ciência; Vol. 26 No. 1 (2011); 16 - 21
Revista Odonto Ciência; v. 26 n. 1 (2011); 16 - 21
1980-6523
0102-9460
reponame:Revista odonto ciência (Online)
instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
instname_str Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron_str PUC_RS
institution PUC_RS
reponame_str Revista odonto ciência (Online)
collection Revista odonto ciência (Online)
repository.name.fl_str_mv Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
repository.mail.fl_str_mv ||odontociencia@pucrs.br
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