Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?
Autor(a) principal: | |
---|---|
Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10451/54361 |
Resumo: | © The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons. org/licenses/by/4.0/ |
id |
RCAP_10e8ef26c1da65d6a0f77d21ad009a64 |
---|---|
oai_identifier_str |
oai:repositorio.ul.pt:10451/54361 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?© The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons. org/licenses/by/4.0/A consensus has yet to emerge whether deep brain stimulation (DBS) for treatment-refractory obsessive-compulsive disorder (OCD) can be considered an established therapy. In 2014, the World Society for Stereotactic and Functional Neurosurgery (WSSFN) published consensus guidelines stating that a therapy becomes established when "at least two blinded randomized controlled clinical trials from two different groups of researchers are published, both reporting an acceptable risk-benefit ratio, at least comparable with other existing therapies. The clinical trials should be on the same brain area for the same psychiatric indication." The authors have now compiled the available evidence to make a clear statement on whether DBS for OCD is established therapy. Two blinded randomized controlled trials have been published, one with level I evidence (Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score improved 37% during stimulation on), the other with level II evidence (25% improvement). A clinical cohort study (N = 70) showed 40% Y-BOCS score improvement during DBS, and a prospective international multi-center study 42% improvement (N = 30). The WSSFN states that electrical stimulation for otherwise treatment refractory OCD using a multipolar electrode implanted in the ventral anterior capsule region (including bed nucleus of stria terminalis and nucleus accumbens) remains investigational. It represents an emerging, but not yet established therapy. A multidisciplinary team involving psychiatrists and neurosurgeons is a prerequisite for such therapy, and the future of surgical treatment of psychiatric patients remains in the realm of the psychiatrist.Springer NatureRepositório da Universidade de LisboaWu, HemmingsHariz, MarwanVisser-Vandewalle, VeerleZrinzo, LudvicCoenen, Volker A.Sheth, Sameer A.Bervoets, ChrisNaesström, MatildaBlomstedt, PatricCoyne, TerryHamani, ClementSlavin, KonstantinKrauss, Joachim K.Kahl, Kai G.Taira, TakaomiZhang, ChenchengSun, BominToda, HirokiSchlaepfer, ThomasChang, Jin WooRégis, JeanSchuurman, RickSchulder, MichaelDoshi, PareshMosley, PhilipPoologaindran, AnujanLázaro-Muñoz, GabrielPepper, JoshuaSchechtmann, GastonFytagoridis, AndersHuys, DanielFerreira, António GonçalvesD’Haese, Pierre-FrançoisNeimat, JosephBroggi, GiovanniVilela-Filho, OsvaldoVoges, JürgenAlkhani, AhmedNakajima, TakeshiRichieri, RaphaelleDjurfeldt, DianaFontaine, PhilippeMartinez-Alvarez, RobertoOkamura, YasushiChandler, JenniferWatanabe, KatsushigeBarcia, Juan A.Reneses, BlancaLozano, AndresGabriëls, LoesDe Salles, AntonioHalpern, Casey H.Matthews, KeithFins, Joseph J.Nuttin, Bart2022-09-07T14:55:53Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/54361engMol Psychiatry. 2021 Jan;26(1):60-651359-418410.1038/s41380-020-00933-x1476-5578info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:00:08Zoai:repositorio.ul.pt:10451/54361Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:04:52.946088Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy? |
title |
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy? |
spellingShingle |
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy? Wu, Hemmings |
title_short |
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy? |
title_full |
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy? |
title_fullStr |
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy? |
title_full_unstemmed |
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy? |
title_sort |
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy? |
author |
Wu, Hemmings |
author_facet |
Wu, Hemmings Hariz, Marwan Visser-Vandewalle, Veerle Zrinzo, Ludvic Coenen, Volker A. Sheth, Sameer A. Bervoets, Chris Naesström, Matilda Blomstedt, Patric Coyne, Terry Hamani, Clement Slavin, Konstantin Krauss, Joachim K. Kahl, Kai G. Taira, Takaomi Zhang, Chencheng Sun, Bomin Toda, Hiroki Schlaepfer, Thomas Chang, Jin Woo Régis, Jean Schuurman, Rick Schulder, Michael Doshi, Paresh Mosley, Philip Poologaindran, Anujan Lázaro-Muñoz, Gabriel Pepper, Joshua Schechtmann, Gaston Fytagoridis, Anders Huys, Daniel Ferreira, António Gonçalves D’Haese, Pierre-François Neimat, Joseph Broggi, Giovanni Vilela-Filho, Osvaldo Voges, Jürgen Alkhani, Ahmed Nakajima, Takeshi Richieri, Raphaelle Djurfeldt, Diana Fontaine, Philippe Martinez-Alvarez, Roberto Okamura, Yasushi Chandler, Jennifer Watanabe, Katsushige Barcia, Juan A. Reneses, Blanca Lozano, Andres Gabriëls, Loes De Salles, Antonio Halpern, Casey H. Matthews, Keith Fins, Joseph J. Nuttin, Bart |
author_role |
author |
author2 |
Hariz, Marwan Visser-Vandewalle, Veerle Zrinzo, Ludvic Coenen, Volker A. Sheth, Sameer A. Bervoets, Chris Naesström, Matilda Blomstedt, Patric Coyne, Terry Hamani, Clement Slavin, Konstantin Krauss, Joachim K. Kahl, Kai G. Taira, Takaomi Zhang, Chencheng Sun, Bomin Toda, Hiroki Schlaepfer, Thomas Chang, Jin Woo Régis, Jean Schuurman, Rick Schulder, Michael Doshi, Paresh Mosley, Philip Poologaindran, Anujan Lázaro-Muñoz, Gabriel Pepper, Joshua Schechtmann, Gaston Fytagoridis, Anders Huys, Daniel Ferreira, António Gonçalves D’Haese, Pierre-François Neimat, Joseph Broggi, Giovanni Vilela-Filho, Osvaldo Voges, Jürgen Alkhani, Ahmed Nakajima, Takeshi Richieri, Raphaelle Djurfeldt, Diana Fontaine, Philippe Martinez-Alvarez, Roberto Okamura, Yasushi Chandler, Jennifer Watanabe, Katsushige Barcia, Juan A. Reneses, Blanca Lozano, Andres Gabriëls, Loes De Salles, Antonio Halpern, Casey H. Matthews, Keith Fins, Joseph J. Nuttin, Bart |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
dc.contributor.author.fl_str_mv |
Wu, Hemmings Hariz, Marwan Visser-Vandewalle, Veerle Zrinzo, Ludvic Coenen, Volker A. Sheth, Sameer A. Bervoets, Chris Naesström, Matilda Blomstedt, Patric Coyne, Terry Hamani, Clement Slavin, Konstantin Krauss, Joachim K. Kahl, Kai G. Taira, Takaomi Zhang, Chencheng Sun, Bomin Toda, Hiroki Schlaepfer, Thomas Chang, Jin Woo Régis, Jean Schuurman, Rick Schulder, Michael Doshi, Paresh Mosley, Philip Poologaindran, Anujan Lázaro-Muñoz, Gabriel Pepper, Joshua Schechtmann, Gaston Fytagoridis, Anders Huys, Daniel Ferreira, António Gonçalves D’Haese, Pierre-François Neimat, Joseph Broggi, Giovanni Vilela-Filho, Osvaldo Voges, Jürgen Alkhani, Ahmed Nakajima, Takeshi Richieri, Raphaelle Djurfeldt, Diana Fontaine, Philippe Martinez-Alvarez, Roberto Okamura, Yasushi Chandler, Jennifer Watanabe, Katsushige Barcia, Juan A. Reneses, Blanca Lozano, Andres Gabriëls, Loes De Salles, Antonio Halpern, Casey H. Matthews, Keith Fins, Joseph J. Nuttin, Bart |
description |
© The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons. org/licenses/by/4.0/ |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020 2020-01-01T00:00:00Z 2022-09-07T14:55:53Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10451/54361 |
url |
http://hdl.handle.net/10451/54361 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Mol Psychiatry. 2021 Jan;26(1):60-65 1359-4184 10.1038/s41380-020-00933-x 1476-5578 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Springer Nature |
publisher.none.fl_str_mv |
Springer Nature |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799134600377663488 |