Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?

Detalhes bibliográficos
Autor(a) principal: Wu, Hemmings
Data de Publicação: 2020
Outros Autores: Hariz, Marwan, Visser-Vandewalle, Veerle, Zrinzo, Ludvic, Coenen, Volker A., Sheth, Sameer A., Bervoets, Chris, Naesström, Matilda, Blomstedt, Patric, Coyne, Terry, Hamani, Clement, Slavin, Konstantin, Krauss, Joachim K., Kahl, Kai G., Taira, Takaomi, Zhang, Chencheng, Sun, Bomin, Toda, Hiroki, Schlaepfer, Thomas, Chang, Jin Woo, Régis, Jean, Schuurman, Rick, Schulder, Michael, Doshi, Paresh, Mosley, Philip, Poologaindran, Anujan, Lázaro-Muñoz, Gabriel, Pepper, Joshua, Schechtmann, Gaston, Fytagoridis, Anders, Huys, Daniel, Ferreira, António Gonçalves, D’Haese, Pierre-François, Neimat, Joseph, Broggi, Giovanni, Vilela-Filho, Osvaldo, Voges, Jürgen, Alkhani, Ahmed, Nakajima, Takeshi, Richieri, Raphaelle, Djurfeldt, Diana, Fontaine, Philippe, Martinez-Alvarez, Roberto, Okamura, Yasushi, Chandler, Jennifer, Watanabe, Katsushige, Barcia, Juan A., Reneses, Blanca, Lozano, Andres, Gabriëls, Loes, De Salles, Antonio, Halpern, Casey H., Matthews, Keith, Fins, Joseph J., Nuttin, Bart
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/54361
Resumo: © The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons. org/licenses/by/4.0/
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spelling Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?© The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons. org/licenses/by/4.0/A consensus has yet to emerge whether deep brain stimulation (DBS) for treatment-refractory obsessive-compulsive disorder (OCD) can be considered an established therapy. In 2014, the World Society for Stereotactic and Functional Neurosurgery (WSSFN) published consensus guidelines stating that a therapy becomes established when "at least two blinded randomized controlled clinical trials from two different groups of researchers are published, both reporting an acceptable risk-benefit ratio, at least comparable with other existing therapies. The clinical trials should be on the same brain area for the same psychiatric indication." The authors have now compiled the available evidence to make a clear statement on whether DBS for OCD is established therapy. Two blinded randomized controlled trials have been published, one with level I evidence (Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score improved 37% during stimulation on), the other with level II evidence (25% improvement). A clinical cohort study (N = 70) showed 40% Y-BOCS score improvement during DBS, and a prospective international multi-center study 42% improvement (N = 30). The WSSFN states that electrical stimulation for otherwise treatment refractory OCD using a multipolar electrode implanted in the ventral anterior capsule region (including bed nucleus of stria terminalis and nucleus accumbens) remains investigational. It represents an emerging, but not yet established therapy. A multidisciplinary team involving psychiatrists and neurosurgeons is a prerequisite for such therapy, and the future of surgical treatment of psychiatric patients remains in the realm of the psychiatrist.Springer NatureRepositório da Universidade de LisboaWu, HemmingsHariz, MarwanVisser-Vandewalle, VeerleZrinzo, LudvicCoenen, Volker A.Sheth, Sameer A.Bervoets, ChrisNaesström, MatildaBlomstedt, PatricCoyne, TerryHamani, ClementSlavin, KonstantinKrauss, Joachim K.Kahl, Kai G.Taira, TakaomiZhang, ChenchengSun, BominToda, HirokiSchlaepfer, ThomasChang, Jin WooRégis, JeanSchuurman, RickSchulder, MichaelDoshi, PareshMosley, PhilipPoologaindran, AnujanLázaro-Muñoz, GabrielPepper, JoshuaSchechtmann, GastonFytagoridis, AndersHuys, DanielFerreira, António GonçalvesD’Haese, Pierre-FrançoisNeimat, JosephBroggi, GiovanniVilela-Filho, OsvaldoVoges, JürgenAlkhani, AhmedNakajima, TakeshiRichieri, RaphaelleDjurfeldt, DianaFontaine, PhilippeMartinez-Alvarez, RobertoOkamura, YasushiChandler, JenniferWatanabe, KatsushigeBarcia, Juan A.Reneses, BlancaLozano, AndresGabriëls, LoesDe Salles, AntonioHalpern, Casey H.Matthews, KeithFins, Joseph J.Nuttin, Bart2022-09-07T14:55:53Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/54361engMol Psychiatry. 2021 Jan;26(1):60-651359-418410.1038/s41380-020-00933-x1476-5578info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:00:08Zoai:repositorio.ul.pt:10451/54361Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:04:52.946088Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?
title Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?
spellingShingle Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?
Wu, Hemmings
title_short Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?
title_full Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?
title_fullStr Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?
title_full_unstemmed Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?
title_sort Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?
author Wu, Hemmings
author_facet Wu, Hemmings
Hariz, Marwan
Visser-Vandewalle, Veerle
Zrinzo, Ludvic
Coenen, Volker A.
Sheth, Sameer A.
Bervoets, Chris
Naesström, Matilda
Blomstedt, Patric
Coyne, Terry
Hamani, Clement
Slavin, Konstantin
Krauss, Joachim K.
Kahl, Kai G.
Taira, Takaomi
Zhang, Chencheng
Sun, Bomin
Toda, Hiroki
Schlaepfer, Thomas
Chang, Jin Woo
Régis, Jean
Schuurman, Rick
Schulder, Michael
Doshi, Paresh
Mosley, Philip
Poologaindran, Anujan
Lázaro-Muñoz, Gabriel
Pepper, Joshua
Schechtmann, Gaston
Fytagoridis, Anders
Huys, Daniel
Ferreira, António Gonçalves
D’Haese, Pierre-François
Neimat, Joseph
Broggi, Giovanni
Vilela-Filho, Osvaldo
Voges, Jürgen
Alkhani, Ahmed
Nakajima, Takeshi
Richieri, Raphaelle
Djurfeldt, Diana
Fontaine, Philippe
Martinez-Alvarez, Roberto
Okamura, Yasushi
Chandler, Jennifer
Watanabe, Katsushige
Barcia, Juan A.
Reneses, Blanca
Lozano, Andres
Gabriëls, Loes
De Salles, Antonio
Halpern, Casey H.
Matthews, Keith
Fins, Joseph J.
Nuttin, Bart
author_role author
author2 Hariz, Marwan
Visser-Vandewalle, Veerle
Zrinzo, Ludvic
Coenen, Volker A.
Sheth, Sameer A.
Bervoets, Chris
Naesström, Matilda
Blomstedt, Patric
Coyne, Terry
Hamani, Clement
Slavin, Konstantin
Krauss, Joachim K.
Kahl, Kai G.
Taira, Takaomi
Zhang, Chencheng
Sun, Bomin
Toda, Hiroki
Schlaepfer, Thomas
Chang, Jin Woo
Régis, Jean
Schuurman, Rick
Schulder, Michael
Doshi, Paresh
Mosley, Philip
Poologaindran, Anujan
Lázaro-Muñoz, Gabriel
Pepper, Joshua
Schechtmann, Gaston
Fytagoridis, Anders
Huys, Daniel
Ferreira, António Gonçalves
D’Haese, Pierre-François
Neimat, Joseph
Broggi, Giovanni
Vilela-Filho, Osvaldo
Voges, Jürgen
Alkhani, Ahmed
Nakajima, Takeshi
Richieri, Raphaelle
Djurfeldt, Diana
Fontaine, Philippe
Martinez-Alvarez, Roberto
Okamura, Yasushi
Chandler, Jennifer
Watanabe, Katsushige
Barcia, Juan A.
Reneses, Blanca
Lozano, Andres
Gabriëls, Loes
De Salles, Antonio
Halpern, Casey H.
Matthews, Keith
Fins, Joseph J.
Nuttin, Bart
author2_role author
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dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Wu, Hemmings
Hariz, Marwan
Visser-Vandewalle, Veerle
Zrinzo, Ludvic
Coenen, Volker A.
Sheth, Sameer A.
Bervoets, Chris
Naesström, Matilda
Blomstedt, Patric
Coyne, Terry
Hamani, Clement
Slavin, Konstantin
Krauss, Joachim K.
Kahl, Kai G.
Taira, Takaomi
Zhang, Chencheng
Sun, Bomin
Toda, Hiroki
Schlaepfer, Thomas
Chang, Jin Woo
Régis, Jean
Schuurman, Rick
Schulder, Michael
Doshi, Paresh
Mosley, Philip
Poologaindran, Anujan
Lázaro-Muñoz, Gabriel
Pepper, Joshua
Schechtmann, Gaston
Fytagoridis, Anders
Huys, Daniel
Ferreira, António Gonçalves
D’Haese, Pierre-François
Neimat, Joseph
Broggi, Giovanni
Vilela-Filho, Osvaldo
Voges, Jürgen
Alkhani, Ahmed
Nakajima, Takeshi
Richieri, Raphaelle
Djurfeldt, Diana
Fontaine, Philippe
Martinez-Alvarez, Roberto
Okamura, Yasushi
Chandler, Jennifer
Watanabe, Katsushige
Barcia, Juan A.
Reneses, Blanca
Lozano, Andres
Gabriëls, Loes
De Salles, Antonio
Halpern, Casey H.
Matthews, Keith
Fins, Joseph J.
Nuttin, Bart
description © The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons. org/licenses/by/4.0/
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
2022-09-07T14:55:53Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/54361
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dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv Mol Psychiatry. 2021 Jan;26(1):60-65
1359-4184
10.1038/s41380-020-00933-x
1476-5578
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