A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cells

Detalhes bibliográficos
Autor(a) principal: Zhu, Beitong
Data de Publicação: 2021
Outros Autores: Wu, Xiaoli, Rodrigues, João, Hu, Xichao, Sheng, Ruilong, Bao, Guang-Ming
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.13/4088
Resumo: Hydrazine (N2H4) and ClO− are very harmful for public health, hence it is important and necessary to monitor them in living cells. Herein, we rationally designed and synthesized a dual-analytes responsive fluorescent sensor PTMQ for distinguishing detection of N2H4 and ClO−. PTMQ underwent N2H4-induced double bond cleavage, affording colorimetric and green fluorescence enhancement with good selectivity and a low detection limit (89 nM). On the other hand, PTMQ underwent ClO−-induced sulfur oxidation and displayed red fluorescence lighting-up response towards ClO− with good selectivity, rapid response (<0.2 min) and a low detection limit (58 nM). Moreover, PTMQ was successfully employed for in-situ imaging of N2H4 and ClO− in living cells
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spelling A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cellsFluorescent probeDual-analytesN2H4ClO−BioimagingLiving cells.Faculdade de Ciências Exatas e da EngenhariaCentro de Química da MadeiraHydrazine (N2H4) and ClO− are very harmful for public health, hence it is important and necessary to monitor them in living cells. Herein, we rationally designed and synthesized a dual-analytes responsive fluorescent sensor PTMQ for distinguishing detection of N2H4 and ClO−. PTMQ underwent N2H4-induced double bond cleavage, affording colorimetric and green fluorescence enhancement with good selectivity and a low detection limit (89 nM). On the other hand, PTMQ underwent ClO−-induced sulfur oxidation and displayed red fluorescence lighting-up response towards ClO− with good selectivity, rapid response (<0.2 min) and a low detection limit (58 nM). Moreover, PTMQ was successfully employed for in-situ imaging of N2H4 and ClO− in living cellsElsevierDigitUMaZhu, BeitongWu, XiaoliRodrigues, JoãoHu, XichaoSheng, RuilongBao, Guang-Ming2022-02-17T10:59:42Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.13/4088engZhu, B., Wu, X., Rodrigues, J., Hu, X., Sheng, R., & Bao, G. M. (2021). A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cells. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 246, 118953. https://doi.org/10.1016/j.saa.2020.11895310.1016/j.saa.2020.118953info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-17T05:58:04Zoai:digituma.uma.pt:10400.13/4088Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:07:54.803012Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cells
title A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cells
spellingShingle A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cells
Zhu, Beitong
Fluorescent probe
Dual-analytes
N2H4
ClO−
Bioimaging
Living cells
.
Faculdade de Ciências Exatas e da Engenharia
Centro de Química da Madeira
title_short A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cells
title_full A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cells
title_fullStr A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cells
title_full_unstemmed A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cells
title_sort A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cells
author Zhu, Beitong
author_facet Zhu, Beitong
Wu, Xiaoli
Rodrigues, João
Hu, Xichao
Sheng, Ruilong
Bao, Guang-Ming
author_role author
author2 Wu, Xiaoli
Rodrigues, João
Hu, Xichao
Sheng, Ruilong
Bao, Guang-Ming
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv DigitUMa
dc.contributor.author.fl_str_mv Zhu, Beitong
Wu, Xiaoli
Rodrigues, João
Hu, Xichao
Sheng, Ruilong
Bao, Guang-Ming
dc.subject.por.fl_str_mv Fluorescent probe
Dual-analytes
N2H4
ClO−
Bioimaging
Living cells
.
Faculdade de Ciências Exatas e da Engenharia
Centro de Química da Madeira
topic Fluorescent probe
Dual-analytes
N2H4
ClO−
Bioimaging
Living cells
.
Faculdade de Ciências Exatas e da Engenharia
Centro de Química da Madeira
description Hydrazine (N2H4) and ClO− are very harmful for public health, hence it is important and necessary to monitor them in living cells. Herein, we rationally designed and synthesized a dual-analytes responsive fluorescent sensor PTMQ for distinguishing detection of N2H4 and ClO−. PTMQ underwent N2H4-induced double bond cleavage, affording colorimetric and green fluorescence enhancement with good selectivity and a low detection limit (89 nM). On the other hand, PTMQ underwent ClO−-induced sulfur oxidation and displayed red fluorescence lighting-up response towards ClO− with good selectivity, rapid response (<0.2 min) and a low detection limit (58 nM). Moreover, PTMQ was successfully employed for in-situ imaging of N2H4 and ClO− in living cells
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-01-01T00:00:00Z
2022-02-17T10:59:42Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.13/4088
url http://hdl.handle.net/10400.13/4088
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Zhu, B., Wu, X., Rodrigues, J., Hu, X., Sheng, R., & Bao, G. M. (2021). A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cells. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 246, 118953. https://doi.org/10.1016/j.saa.2020.118953
10.1016/j.saa.2020.118953
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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