Multiple lineages of nematode-Wolbachia symbiosis in supergroup F and convergent loss of bacterioferritin in filarial Wolbachia

Detalhes bibliográficos
Autor(a) principal: Sinha, Amit
Data de Publicação: 2023
Outros Autores: Li, Zhiru, Poole, Catherine B, Ettwiller, Laurence, Lima, Nathália F, Ferreira, Marcelo U, Fombad, Fanny F, Wanji, Samuel, Carlow, Clotilde K S
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/160252
Resumo: © The Author(s) 2023. Published by Oxford University Press on behalf of Society for Molecular Biology and Evolution.
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spelling Multiple lineages of nematode-Wolbachia symbiosis in supergroup F and convergent loss of bacterioferritin in filarial WolbachiaWolbachiafilariaevolutionbacterioferritinhemephylogenomicsQR MicrobiologyRA Public aspects of medicineEpidemiologyInfectious DiseasesMicrobiologySDG 3 - Good Health and Well-being© The Author(s) 2023. Published by Oxford University Press on behalf of Society for Molecular Biology and Evolution.The intracellular endosymbiotic proteobacteria Wolbachia have evolved across the phyla nematoda and arthropoda. In Wolbachia phylogeny, supergroup F is the only clade known so far with members from both arthropod and filarial nematode hosts and therefore can provide unique insights into their evolution and biology. In this study, 4 new supergroup F Wolbachia genomes have been assembled using a metagenomic assembly and binning approach, wMoz and wMpe from the human filarial parasites Mansonella ozzardi and Mansonella perstans, and wOcae and wMoviF from the blue mason bee Osmia caerulescens and the sheep ked Melophagus ovinus respectively. A comprehensive phylogenomic analysis revealed two distinct lineages of filarial Wolbachia in supergroup F, indicating multiple horizontal transfer events between arthropod and nematode hosts. The analysis also reveals that the evolution of Wolbachia-filaria symbioses is accompanied by a convergent pseudogenization and loss of the bacterioferritin gene, a phenomenon found to be shared by all filarial Wolbachia, even those outside supergroup F. These observations indicate that differences in heme metabolism might be a key feature distinguishing filarial and arthropod Wolbachia. The new genomes provide a valuable resource for further studies on symbiosis, evolution, and the discovery of new antibiotics to treat mansonellosis.Individual Health Care (IHC)Global Health and Tropical Medicine (GHTM)Instituto de Higiene e Medicina Tropical (IHMT)RUNSinha, AmitLi, ZhiruPoole, Catherine BEttwiller, LaurenceLima, Nathália FFerreira, Marcelo UFombad, Fanny FWanji, SamuelCarlow, Clotilde K S2023-11-21T22:21:14Z2023-05-082023-05-08T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article21application/pdfhttp://hdl.handle.net/10362/160252eng1759-6653PURE: 63157656https://doi.org/10.1093/gbe/evad073info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:42:50Zoai:run.unl.pt:10362/160252Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:57:56.095102Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Multiple lineages of nematode-Wolbachia symbiosis in supergroup F and convergent loss of bacterioferritin in filarial Wolbachia
title Multiple lineages of nematode-Wolbachia symbiosis in supergroup F and convergent loss of bacterioferritin in filarial Wolbachia
spellingShingle Multiple lineages of nematode-Wolbachia symbiosis in supergroup F and convergent loss of bacterioferritin in filarial Wolbachia
Sinha, Amit
Wolbachia
filaria
evolution
bacterioferritin
heme
phylogenomics
QR Microbiology
RA Public aspects of medicine
Epidemiology
Infectious Diseases
Microbiology
SDG 3 - Good Health and Well-being
title_short Multiple lineages of nematode-Wolbachia symbiosis in supergroup F and convergent loss of bacterioferritin in filarial Wolbachia
title_full Multiple lineages of nematode-Wolbachia symbiosis in supergroup F and convergent loss of bacterioferritin in filarial Wolbachia
title_fullStr Multiple lineages of nematode-Wolbachia symbiosis in supergroup F and convergent loss of bacterioferritin in filarial Wolbachia
title_full_unstemmed Multiple lineages of nematode-Wolbachia symbiosis in supergroup F and convergent loss of bacterioferritin in filarial Wolbachia
title_sort Multiple lineages of nematode-Wolbachia symbiosis in supergroup F and convergent loss of bacterioferritin in filarial Wolbachia
author Sinha, Amit
author_facet Sinha, Amit
Li, Zhiru
Poole, Catherine B
Ettwiller, Laurence
Lima, Nathália F
Ferreira, Marcelo U
Fombad, Fanny F
Wanji, Samuel
Carlow, Clotilde K S
author_role author
author2 Li, Zhiru
Poole, Catherine B
Ettwiller, Laurence
Lima, Nathália F
Ferreira, Marcelo U
Fombad, Fanny F
Wanji, Samuel
Carlow, Clotilde K S
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Individual Health Care (IHC)
Global Health and Tropical Medicine (GHTM)
Instituto de Higiene e Medicina Tropical (IHMT)
RUN
dc.contributor.author.fl_str_mv Sinha, Amit
Li, Zhiru
Poole, Catherine B
Ettwiller, Laurence
Lima, Nathália F
Ferreira, Marcelo U
Fombad, Fanny F
Wanji, Samuel
Carlow, Clotilde K S
dc.subject.por.fl_str_mv Wolbachia
filaria
evolution
bacterioferritin
heme
phylogenomics
QR Microbiology
RA Public aspects of medicine
Epidemiology
Infectious Diseases
Microbiology
SDG 3 - Good Health and Well-being
topic Wolbachia
filaria
evolution
bacterioferritin
heme
phylogenomics
QR Microbiology
RA Public aspects of medicine
Epidemiology
Infectious Diseases
Microbiology
SDG 3 - Good Health and Well-being
description © The Author(s) 2023. Published by Oxford University Press on behalf of Society for Molecular Biology and Evolution.
publishDate 2023
dc.date.none.fl_str_mv 2023-11-21T22:21:14Z
2023-05-08
2023-05-08T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/160252
url http://hdl.handle.net/10362/160252
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1759-6653
PURE: 63157656
https://doi.org/10.1093/gbe/evad073
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 21
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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