Nontoxic glasses: Preparation, structural, electrical and biological properties

Detalhes bibliográficos
Autor(a) principal: Gavinho, Sílvia R.
Data de Publicação: 2019
Outros Autores: Prezas, Pedro R., Ramos, Diogo J., Sá-Nogueira, Isabel, Borges, Joao P., Lança, M. Carmo, Silva, Jorges C., Henriques, Célia M. R., Pires, Eduardo, Kumar, Jakka Suresh, Graça, M. P. F.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/112012
Resumo: The authors are grateful by the FEDER funds through the COMPETE 2020 Program and National Funds through FCT?Portuguese Foundation for Science and Technology under the project UID/CTM/50025/2013, UCIBIO, REQUIMTE UID/Multi/04378/2013, and DENTALBLAST project (ref. n? 17956).
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spelling Nontoxic glasses: Preparation, structural, electrical and biological propertiesantibacterial propertiesbioactive glassbiomaterialcytotoxicityelectrical propertiesCeramics and CompositesCondensed Matter PhysicsMarketingMaterials ChemistryThe authors are grateful by the FEDER funds through the COMPETE 2020 Program and National Funds through FCT?Portuguese Foundation for Science and Technology under the project UID/CTM/50025/2013, UCIBIO, REQUIMTE UID/Multi/04378/2013, and DENTALBLAST project (ref. n? 17956).Bacterial infections affect about 1 in 5 patients who receive a dental implant within 5 years of surgery. To avoid the implant rejection it is necessary for the development of innovative biomaterials, with addition or substitution of the ions, for implant coatings that promote a strong bond with the new host bone and antibacterial action. The objective of this work was to synthesize a bioactive glass with different silver concentrations to evaluate their antibacterial performance. The glasses were synthesized with up to 2% silver content by melt-quenching. Structural, morphological, biological, and electrical properties of all samples were studied. The biological behavior was evaluated through cytotoxicity tests and antibacterial activity. The structural analysis shows that the introduction of silver do not promote significant changes, not altering the advantageous properties of the bioglass of the bioglass. It was verified that the glasses with a silver content from 0.5% to 2%, completely prevented the growth of both Staphylococcus aureus and Escherichia coli while being nontoxic toward mammalian cells. Therefore, these bioglasses are promising materials to be used in the production of dental implants with antimicrobial activity.CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)DCM - Departamento de Ciência dos MateriaisUCIBIO - Applied Molecular Biosciences UnitDCV - Departamento de Ciências da VidaRUNGavinho, Sílvia R.Prezas, Pedro R.Ramos, Diogo J.Sá-Nogueira, IsabelBorges, Joao P.Lança, M. CarmoSilva, Jorges C.Henriques, Célia M. R.Pires, EduardoKumar, Jakka SureshGraça, M. P. F.2021-02-17T23:24:26Z2019-09-012019-09-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/112012eng1546-542XPURE: 13010681https://doi.org/10.1111/ijac.13243info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:55:44Zoai:run.unl.pt:10362/112012Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:42:02.876621Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Nontoxic glasses: Preparation, structural, electrical and biological properties
title Nontoxic glasses: Preparation, structural, electrical and biological properties
spellingShingle Nontoxic glasses: Preparation, structural, electrical and biological properties
Gavinho, Sílvia R.
antibacterial properties
bioactive glass
biomaterial
cytotoxicity
electrical properties
Ceramics and Composites
Condensed Matter Physics
Marketing
Materials Chemistry
title_short Nontoxic glasses: Preparation, structural, electrical and biological properties
title_full Nontoxic glasses: Preparation, structural, electrical and biological properties
title_fullStr Nontoxic glasses: Preparation, structural, electrical and biological properties
title_full_unstemmed Nontoxic glasses: Preparation, structural, electrical and biological properties
title_sort Nontoxic glasses: Preparation, structural, electrical and biological properties
author Gavinho, Sílvia R.
author_facet Gavinho, Sílvia R.
Prezas, Pedro R.
Ramos, Diogo J.
Sá-Nogueira, Isabel
Borges, Joao P.
Lança, M. Carmo
Silva, Jorges C.
Henriques, Célia M. R.
Pires, Eduardo
Kumar, Jakka Suresh
Graça, M. P. F.
author_role author
author2 Prezas, Pedro R.
Ramos, Diogo J.
Sá-Nogueira, Isabel
Borges, Joao P.
Lança, M. Carmo
Silva, Jorges C.
Henriques, Célia M. R.
Pires, Eduardo
Kumar, Jakka Suresh
Graça, M. P. F.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)
DCM - Departamento de Ciência dos Materiais
UCIBIO - Applied Molecular Biosciences Unit
DCV - Departamento de Ciências da Vida
RUN
dc.contributor.author.fl_str_mv Gavinho, Sílvia R.
Prezas, Pedro R.
Ramos, Diogo J.
Sá-Nogueira, Isabel
Borges, Joao P.
Lança, M. Carmo
Silva, Jorges C.
Henriques, Célia M. R.
Pires, Eduardo
Kumar, Jakka Suresh
Graça, M. P. F.
dc.subject.por.fl_str_mv antibacterial properties
bioactive glass
biomaterial
cytotoxicity
electrical properties
Ceramics and Composites
Condensed Matter Physics
Marketing
Materials Chemistry
topic antibacterial properties
bioactive glass
biomaterial
cytotoxicity
electrical properties
Ceramics and Composites
Condensed Matter Physics
Marketing
Materials Chemistry
description The authors are grateful by the FEDER funds through the COMPETE 2020 Program and National Funds through FCT?Portuguese Foundation for Science and Technology under the project UID/CTM/50025/2013, UCIBIO, REQUIMTE UID/Multi/04378/2013, and DENTALBLAST project (ref. n? 17956).
publishDate 2019
dc.date.none.fl_str_mv 2019-09-01
2019-09-01T00:00:00Z
2021-02-17T23:24:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/112012
url http://hdl.handle.net/10362/112012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1546-542X
PURE: 13010681
https://doi.org/10.1111/ijac.13243
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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