Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study

Detalhes bibliográficos
Autor(a) principal: Grundmann, Hajo
Data de Publicação: 2017
Outros Autores: Glasner, Corinna, Albiger, Barbara, Aanensen, David M., Tomlinson, Chris T., Andrasević, Arjana Tambić, Cantón, Rafael, Carmeli, Yehuda, Friedrich, Alexander W., Giske, Christian G., Glupczynski, Youri, Gniadkowski, Marek, Livermore, David M., Nordmann, Patrice, Poirel, Laurent, Rossolini, Gian M., Seifert, Harald, Vatopoulos, Alkiviadis, Walsh, Timothy, Woodford, Neil, Monnet, Dominique L., EuSCAPE Working Group, Koraqi, A.., Lacej, D., Apfalter, P., Hartl, R., Glupczynski, Y., Huang, T.D., Strateva, T, Marteva-Proevska, Y., Tambic, Andrasevic A., Butic, I., Pieridou-Bagatzouni, D., Maikanti-Charalampous, P., Hrabak, J., Zemlickova, H., Hammerum, A., Jakobsen, L., Ivanova, M., Pavelkovich, A., Jalava, J., Österblad, M., Dortet, L., Vaux, S., Kaase, M., Gatermann, S.G., Vatopoulos, A., Tryfinopoulou, K., Tóth, A., Jánvári, L., Boo, T.W., McGrath, E., Carmeli, Y., Adler, A., Pantosti, A., Monaco, M., Raka, L., Kurti, A., Balode, A., Saule, M., Miciuleviciene, J., Mierauskaite, A., Perrin -Weniger, M., Reichert, P., Nestorova, N., Debattista, S., Mijovic, G., Lopicic, M., Samuelsen, Ø., Haldorsen, B.J., Żabicka, D., Literacka, E., Caniça, M., Manageiro, V., Kaftandzieva, A., Trajkovska-Dokic, E., Damian, M., Lixandru, B., Jelesic, Z., Trudic, A., Niks, M., Schreterova, E., Pirs, M., Cerar, T., Oteo, J., Aracil, B., Giske, C., Sjöström, K., Gür, D., Cakar, A., Woodford, N., Hopkins, K., Wiuff, C., Brown, D.J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/4250
Resumo: The members of the European Survey on Carbapenemase-Producing Enterobacteriaceae, (EuSCAPE) Working Group are: Portugal—Manuela Caniça and Vera Manageiro
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spelling Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational studyEuSCAPEECDCCarbapenemase-producing Klebsiella pneumoniaeCarbapenemase-producing Escherichia coliResistência aos AntimicrobianosThe members of the European Survey on Carbapenemase-Producing Enterobacteriaceae, (EuSCAPE) Working Group are: Portugal—Manuela Caniça and Vera ManageiroBACKGROUND: Gaps in the diagnostic capacity and heterogeneity of national surveillance and reporting standards in Europe make it difficult to contain carbapenemase-producing Enterobacteriaceae. We report the development of a consistent sampling framework and the results of the first structured survey on the occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in European hospitals. METHODS: National expert laboratories recruited hospitals with diagnostic capacities, who collected the first ten carbapenem non-susceptible clinical isolates of K pneumoniae or E coli and ten susceptible same-species comparator isolates and pertinent patient and hospital information. Isolates and data were relayed back to national expert laboratories, which made laboratory-substantiated information available for central analysis. FINDINGS: Between Nov 1, 2013, and April 30, 2014, 455 sentinel hospitals in 36 countries submitted 2703 clinical isolates (2301 [85%] K pneumoniae and 402 (15%) E coli). 850 (37%) of 2301 K pneumoniae samples and 77 (19%) of 402 E coli samples were carbapenemase (KPC, NDM, OXA-48-like, or VIM) producers. The ratio of K pneumoniae to E coli was 11:1. 1·3 patients per 10 000 hospital admissions had positive clinical specimens. Prevalence differed greatly, with the highest rates in Mediterranean and Balkan countries. Carbapenemase-producing K pneumoniae isolates showed high resistance to last-line antibiotics. INTERPRETATION: This initiative shows an encouraging commitment by all participants, and suggests that challenges in the establishment of a continent-wide enhanced sentinel surveillance for carbapenemase-producing Enterobacteriaeceae can be overcome. Strengthening infection control efforts in hospitals is crucial for controlling spread through local and national health care networks.European Centre for Disease Prevention and ControlElsevier: LancetRepositório Científico do Instituto Nacional de SaúdeGrundmann, HajoGlasner, CorinnaAlbiger, BarbaraAanensen, David M.Tomlinson, Chris T.Andrasević, Arjana TambićCantón, RafaelCarmeli, YehudaFriedrich, Alexander W.Giske, Christian G.Glupczynski, YouriGniadkowski, MarekLivermore, David M.Nordmann, PatricePoirel, LaurentRossolini, Gian M.Seifert, HaraldVatopoulos, AlkiviadisWalsh, TimothyWoodford, NeilMonnet, Dominique L.EuSCAPE Working GroupKoraqi, A..Lacej, D.Apfalter, P.Hartl, R.Glupczynski, Y.Huang, T.D.Strateva, TMarteva-Proevska, Y.Tambic, Andrasevic A.Butic, I.Pieridou-Bagatzouni, D.Maikanti-Charalampous, P.Hrabak, J.Zemlickova, H.Hammerum, A.Jakobsen, L.Ivanova, M.Pavelkovich, A.Jalava, J.Österblad, M.Dortet, L.Vaux, S.Kaase, M.Gatermann, S.G.Vatopoulos, A.Tryfinopoulou, K.Tóth, A.Jánvári, L.Boo, T.W.McGrath, E.Carmeli, Y.Adler, A.Pantosti, A.Monaco, M.Raka, L.Kurti, A.Balode, A.Saule, M.Miciuleviciene, J.Mierauskaite, A.Perrin -Weniger, M.Reichert, P.Nestorova, N.Debattista, S.Mijovic, G.Lopicic, M.Samuelsen, Ø.Haldorsen, B.J.Żabicka, D.Literacka, E.Caniça, M.Manageiro, V.Kaftandzieva, A.Trajkovska-Dokic, E.Damian, M.Lixandru, B.Jelesic, Z.Trudic, A.Niks, M.Schreterova, E.Pirs, M.Cerar, T.Oteo, J.Aracil, B.Giske, C.Sjöström, K.Gür, D.Cakar, A.Woodford, N.Hopkins, K.Wiuff, C.Brown, D.J.2017-11-19T01:30:14Z2017-022017-02-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/4250engLancet Infect Dis. 2017 Feb;17(2):153-163. doi: 10.1016/S1473-3099(16)30257-2. Epub 2016 Nov 18.1473-309910.1016/S1473-3099(16)30257-2info:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:40:18Zoai:repositorio.insa.pt:10400.18/4250Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:39:08.808429Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study
title Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study
spellingShingle Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study
Grundmann, Hajo
EuSCAPE
ECDC
Carbapenemase-producing Klebsiella pneumoniae
Carbapenemase-producing Escherichia coli
Resistência aos Antimicrobianos
title_short Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study
title_full Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study
title_fullStr Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study
title_full_unstemmed Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study
title_sort Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study
author Grundmann, Hajo
author_facet Grundmann, Hajo
Glasner, Corinna
Albiger, Barbara
Aanensen, David M.
Tomlinson, Chris T.
Andrasević, Arjana Tambić
Cantón, Rafael
Carmeli, Yehuda
Friedrich, Alexander W.
Giske, Christian G.
Glupczynski, Youri
Gniadkowski, Marek
Livermore, David M.
Nordmann, Patrice
Poirel, Laurent
Rossolini, Gian M.
Seifert, Harald
Vatopoulos, Alkiviadis
Walsh, Timothy
Woodford, Neil
Monnet, Dominique L.
EuSCAPE Working Group
Koraqi, A..
Lacej, D.
Apfalter, P.
Hartl, R.
Glupczynski, Y.
Huang, T.D.
Strateva, T
Marteva-Proevska, Y.
Tambic, Andrasevic A.
Butic, I.
Pieridou-Bagatzouni, D.
Maikanti-Charalampous, P.
Hrabak, J.
Zemlickova, H.
Hammerum, A.
Jakobsen, L.
Ivanova, M.
Pavelkovich, A.
Jalava, J.
Österblad, M.
Dortet, L.
Vaux, S.
Kaase, M.
Gatermann, S.G.
Vatopoulos, A.
Tryfinopoulou, K.
Tóth, A.
Jánvári, L.
Boo, T.W.
McGrath, E.
Carmeli, Y.
Adler, A.
Pantosti, A.
Monaco, M.
Raka, L.
Kurti, A.
Balode, A.
Saule, M.
Miciuleviciene, J.
Mierauskaite, A.
Perrin -Weniger, M.
Reichert, P.
Nestorova, N.
Debattista, S.
Mijovic, G.
Lopicic, M.
Samuelsen, Ø.
Haldorsen, B.J.
Żabicka, D.
Literacka, E.
Caniça, M.
Manageiro, V.
Kaftandzieva, A.
Trajkovska-Dokic, E.
Damian, M.
Lixandru, B.
Jelesic, Z.
Trudic, A.
Niks, M.
Schreterova, E.
Pirs, M.
Cerar, T.
Oteo, J.
Aracil, B.
Giske, C.
Sjöström, K.
Gür, D.
Cakar, A.
Woodford, N.
Hopkins, K.
Wiuff, C.
Brown, D.J.
author_role author
author2 Glasner, Corinna
Albiger, Barbara
Aanensen, David M.
Tomlinson, Chris T.
Andrasević, Arjana Tambić
Cantón, Rafael
Carmeli, Yehuda
Friedrich, Alexander W.
Giske, Christian G.
Glupczynski, Youri
Gniadkowski, Marek
Livermore, David M.
Nordmann, Patrice
Poirel, Laurent
Rossolini, Gian M.
Seifert, Harald
Vatopoulos, Alkiviadis
Walsh, Timothy
Woodford, Neil
Monnet, Dominique L.
EuSCAPE Working Group
Koraqi, A..
Lacej, D.
Apfalter, P.
Hartl, R.
Glupczynski, Y.
Huang, T.D.
Strateva, T
Marteva-Proevska, Y.
Tambic, Andrasevic A.
Butic, I.
Pieridou-Bagatzouni, D.
Maikanti-Charalampous, P.
Hrabak, J.
Zemlickova, H.
Hammerum, A.
Jakobsen, L.
Ivanova, M.
Pavelkovich, A.
Jalava, J.
Österblad, M.
Dortet, L.
Vaux, S.
Kaase, M.
Gatermann, S.G.
Vatopoulos, A.
Tryfinopoulou, K.
Tóth, A.
Jánvári, L.
Boo, T.W.
McGrath, E.
Carmeli, Y.
Adler, A.
Pantosti, A.
Monaco, M.
Raka, L.
Kurti, A.
Balode, A.
Saule, M.
Miciuleviciene, J.
Mierauskaite, A.
Perrin -Weniger, M.
Reichert, P.
Nestorova, N.
Debattista, S.
Mijovic, G.
Lopicic, M.
Samuelsen, Ø.
Haldorsen, B.J.
Żabicka, D.
Literacka, E.
Caniça, M.
Manageiro, V.
Kaftandzieva, A.
Trajkovska-Dokic, E.
Damian, M.
Lixandru, B.
Jelesic, Z.
Trudic, A.
Niks, M.
Schreterova, E.
Pirs, M.
Cerar, T.
Oteo, J.
Aracil, B.
Giske, C.
Sjöström, K.
Gür, D.
Cakar, A.
Woodford, N.
Hopkins, K.
Wiuff, C.
Brown, D.J.
author2_role author
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dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Grundmann, Hajo
Glasner, Corinna
Albiger, Barbara
Aanensen, David M.
Tomlinson, Chris T.
Andrasević, Arjana Tambić
Cantón, Rafael
Carmeli, Yehuda
Friedrich, Alexander W.
Giske, Christian G.
Glupczynski, Youri
Gniadkowski, Marek
Livermore, David M.
Nordmann, Patrice
Poirel, Laurent
Rossolini, Gian M.
Seifert, Harald
Vatopoulos, Alkiviadis
Walsh, Timothy
Woodford, Neil
Monnet, Dominique L.
EuSCAPE Working Group
Koraqi, A..
Lacej, D.
Apfalter, P.
Hartl, R.
Glupczynski, Y.
Huang, T.D.
Strateva, T
Marteva-Proevska, Y.
Tambic, Andrasevic A.
Butic, I.
Pieridou-Bagatzouni, D.
Maikanti-Charalampous, P.
Hrabak, J.
Zemlickova, H.
Hammerum, A.
Jakobsen, L.
Ivanova, M.
Pavelkovich, A.
Jalava, J.
Österblad, M.
Dortet, L.
Vaux, S.
Kaase, M.
Gatermann, S.G.
Vatopoulos, A.
Tryfinopoulou, K.
Tóth, A.
Jánvári, L.
Boo, T.W.
McGrath, E.
Carmeli, Y.
Adler, A.
Pantosti, A.
Monaco, M.
Raka, L.
Kurti, A.
Balode, A.
Saule, M.
Miciuleviciene, J.
Mierauskaite, A.
Perrin -Weniger, M.
Reichert, P.
Nestorova, N.
Debattista, S.
Mijovic, G.
Lopicic, M.
Samuelsen, Ø.
Haldorsen, B.J.
Żabicka, D.
Literacka, E.
Caniça, M.
Manageiro, V.
Kaftandzieva, A.
Trajkovska-Dokic, E.
Damian, M.
Lixandru, B.
Jelesic, Z.
Trudic, A.
Niks, M.
Schreterova, E.
Pirs, M.
Cerar, T.
Oteo, J.
Aracil, B.
Giske, C.
Sjöström, K.
Gür, D.
Cakar, A.
Woodford, N.
Hopkins, K.
Wiuff, C.
Brown, D.J.
dc.subject.por.fl_str_mv EuSCAPE
ECDC
Carbapenemase-producing Klebsiella pneumoniae
Carbapenemase-producing Escherichia coli
Resistência aos Antimicrobianos
topic EuSCAPE
ECDC
Carbapenemase-producing Klebsiella pneumoniae
Carbapenemase-producing Escherichia coli
Resistência aos Antimicrobianos
description The members of the European Survey on Carbapenemase-Producing Enterobacteriaceae, (EuSCAPE) Working Group are: Portugal—Manuela Caniça and Vera Manageiro
publishDate 2017
dc.date.none.fl_str_mv 2017-11-19T01:30:14Z
2017-02
2017-02-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/4250
url http://hdl.handle.net/10400.18/4250
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Lancet Infect Dis. 2017 Feb;17(2):153-163. doi: 10.1016/S1473-3099(16)30257-2. Epub 2016 Nov 18.
1473-3099
10.1016/S1473-3099(16)30257-2
dc.rights.driver.fl_str_mv info:eu-repo/semantics/embargoedAccess
eu_rights_str_mv embargoedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier: Lancet
publisher.none.fl_str_mv Elsevier: Lancet
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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