Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.18/4250 |
Resumo: | The members of the European Survey on Carbapenemase-Producing Enterobacteriaceae, (EuSCAPE) Working Group are: Portugal—Manuela Caniça and Vera Manageiro |
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Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational studyEuSCAPEECDCCarbapenemase-producing Klebsiella pneumoniaeCarbapenemase-producing Escherichia coliResistência aos AntimicrobianosThe members of the European Survey on Carbapenemase-Producing Enterobacteriaceae, (EuSCAPE) Working Group are: Portugal—Manuela Caniça and Vera ManageiroBACKGROUND: Gaps in the diagnostic capacity and heterogeneity of national surveillance and reporting standards in Europe make it difficult to contain carbapenemase-producing Enterobacteriaceae. We report the development of a consistent sampling framework and the results of the first structured survey on the occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in European hospitals. METHODS: National expert laboratories recruited hospitals with diagnostic capacities, who collected the first ten carbapenem non-susceptible clinical isolates of K pneumoniae or E coli and ten susceptible same-species comparator isolates and pertinent patient and hospital information. Isolates and data were relayed back to national expert laboratories, which made laboratory-substantiated information available for central analysis. FINDINGS: Between Nov 1, 2013, and April 30, 2014, 455 sentinel hospitals in 36 countries submitted 2703 clinical isolates (2301 [85%] K pneumoniae and 402 (15%) E coli). 850 (37%) of 2301 K pneumoniae samples and 77 (19%) of 402 E coli samples were carbapenemase (KPC, NDM, OXA-48-like, or VIM) producers. The ratio of K pneumoniae to E coli was 11:1. 1·3 patients per 10 000 hospital admissions had positive clinical specimens. Prevalence differed greatly, with the highest rates in Mediterranean and Balkan countries. Carbapenemase-producing K pneumoniae isolates showed high resistance to last-line antibiotics. INTERPRETATION: This initiative shows an encouraging commitment by all participants, and suggests that challenges in the establishment of a continent-wide enhanced sentinel surveillance for carbapenemase-producing Enterobacteriaeceae can be overcome. Strengthening infection control efforts in hospitals is crucial for controlling spread through local and national health care networks.European Centre for Disease Prevention and ControlElsevier: LancetRepositório Científico do Instituto Nacional de SaúdeGrundmann, HajoGlasner, CorinnaAlbiger, BarbaraAanensen, David M.Tomlinson, Chris T.Andrasević, Arjana TambićCantón, RafaelCarmeli, YehudaFriedrich, Alexander W.Giske, Christian G.Glupczynski, YouriGniadkowski, MarekLivermore, David M.Nordmann, PatricePoirel, LaurentRossolini, Gian M.Seifert, HaraldVatopoulos, AlkiviadisWalsh, TimothyWoodford, NeilMonnet, Dominique L.EuSCAPE Working GroupKoraqi, A..Lacej, D.Apfalter, P.Hartl, R.Glupczynski, Y.Huang, T.D.Strateva, TMarteva-Proevska, Y.Tambic, Andrasevic A.Butic, I.Pieridou-Bagatzouni, D.Maikanti-Charalampous, P.Hrabak, J.Zemlickova, H.Hammerum, A.Jakobsen, L.Ivanova, M.Pavelkovich, A.Jalava, J.Österblad, M.Dortet, L.Vaux, S.Kaase, M.Gatermann, S.G.Vatopoulos, A.Tryfinopoulou, K.Tóth, A.Jánvári, L.Boo, T.W.McGrath, E.Carmeli, Y.Adler, A.Pantosti, A.Monaco, M.Raka, L.Kurti, A.Balode, A.Saule, M.Miciuleviciene, J.Mierauskaite, A.Perrin -Weniger, M.Reichert, P.Nestorova, N.Debattista, S.Mijovic, G.Lopicic, M.Samuelsen, Ø.Haldorsen, B.J.Żabicka, D.Literacka, E.Caniça, M.Manageiro, V.Kaftandzieva, A.Trajkovska-Dokic, E.Damian, M.Lixandru, B.Jelesic, Z.Trudic, A.Niks, M.Schreterova, E.Pirs, M.Cerar, T.Oteo, J.Aracil, B.Giske, C.Sjöström, K.Gür, D.Cakar, A.Woodford, N.Hopkins, K.Wiuff, C.Brown, D.J.2017-11-19T01:30:14Z2017-022017-02-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/4250engLancet Infect Dis. 2017 Feb;17(2):153-163. doi: 10.1016/S1473-3099(16)30257-2. Epub 2016 Nov 18.1473-309910.1016/S1473-3099(16)30257-2info:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:40:18Zoai:repositorio.insa.pt:10400.18/4250Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:39:08.808429Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study |
title |
Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study |
spellingShingle |
Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study Grundmann, Hajo EuSCAPE ECDC Carbapenemase-producing Klebsiella pneumoniae Carbapenemase-producing Escherichia coli Resistência aos Antimicrobianos |
title_short |
Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study |
title_full |
Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study |
title_fullStr |
Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study |
title_full_unstemmed |
Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study |
title_sort |
Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study |
author |
Grundmann, Hajo |
author_facet |
Grundmann, Hajo Glasner, Corinna Albiger, Barbara Aanensen, David M. Tomlinson, Chris T. Andrasević, Arjana Tambić Cantón, Rafael Carmeli, Yehuda Friedrich, Alexander W. Giske, Christian G. Glupczynski, Youri Gniadkowski, Marek Livermore, David M. Nordmann, Patrice Poirel, Laurent Rossolini, Gian M. Seifert, Harald Vatopoulos, Alkiviadis Walsh, Timothy Woodford, Neil Monnet, Dominique L. EuSCAPE Working Group Koraqi, A.. Lacej, D. Apfalter, P. Hartl, R. Glupczynski, Y. Huang, T.D. Strateva, T Marteva-Proevska, Y. Tambic, Andrasevic A. Butic, I. Pieridou-Bagatzouni, D. Maikanti-Charalampous, P. Hrabak, J. Zemlickova, H. Hammerum, A. Jakobsen, L. Ivanova, M. Pavelkovich, A. Jalava, J. Österblad, M. Dortet, L. Vaux, S. Kaase, M. Gatermann, S.G. Vatopoulos, A. Tryfinopoulou, K. Tóth, A. Jánvári, L. Boo, T.W. McGrath, E. Carmeli, Y. Adler, A. Pantosti, A. Monaco, M. Raka, L. Kurti, A. Balode, A. Saule, M. Miciuleviciene, J. Mierauskaite, A. Perrin -Weniger, M. Reichert, P. Nestorova, N. Debattista, S. Mijovic, G. Lopicic, M. Samuelsen, Ø. Haldorsen, B.J. Żabicka, D. Literacka, E. Caniça, M. Manageiro, V. Kaftandzieva, A. Trajkovska-Dokic, E. Damian, M. Lixandru, B. Jelesic, Z. Trudic, A. Niks, M. Schreterova, E. Pirs, M. Cerar, T. Oteo, J. Aracil, B. Giske, C. Sjöström, K. Gür, D. Cakar, A. Woodford, N. Hopkins, K. Wiuff, C. Brown, D.J. |
author_role |
author |
author2 |
Glasner, Corinna Albiger, Barbara Aanensen, David M. Tomlinson, Chris T. Andrasević, Arjana Tambić Cantón, Rafael Carmeli, Yehuda Friedrich, Alexander W. Giske, Christian G. Glupczynski, Youri Gniadkowski, Marek Livermore, David M. Nordmann, Patrice Poirel, Laurent Rossolini, Gian M. Seifert, Harald Vatopoulos, Alkiviadis Walsh, Timothy Woodford, Neil Monnet, Dominique L. EuSCAPE Working Group Koraqi, A.. Lacej, D. Apfalter, P. Hartl, R. Glupczynski, Y. Huang, T.D. Strateva, T Marteva-Proevska, Y. Tambic, Andrasevic A. Butic, I. Pieridou-Bagatzouni, D. Maikanti-Charalampous, P. Hrabak, J. Zemlickova, H. Hammerum, A. Jakobsen, L. Ivanova, M. Pavelkovich, A. Jalava, J. Österblad, M. Dortet, L. Vaux, S. Kaase, M. Gatermann, S.G. Vatopoulos, A. Tryfinopoulou, K. Tóth, A. Jánvári, L. Boo, T.W. McGrath, E. Carmeli, Y. Adler, A. Pantosti, A. Monaco, M. Raka, L. Kurti, A. Balode, A. Saule, M. Miciuleviciene, J. Mierauskaite, A. Perrin -Weniger, M. Reichert, P. Nestorova, N. Debattista, S. Mijovic, G. Lopicic, M. Samuelsen, Ø. Haldorsen, B.J. Żabicka, D. Literacka, E. Caniça, M. Manageiro, V. Kaftandzieva, A. Trajkovska-Dokic, E. Damian, M. Lixandru, B. Jelesic, Z. Trudic, A. Niks, M. Schreterova, E. Pirs, M. Cerar, T. Oteo, J. Aracil, B. Giske, C. Sjöström, K. Gür, D. Cakar, A. Woodford, N. Hopkins, K. Wiuff, C. Brown, D.J. |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Nacional de Saúde |
dc.contributor.author.fl_str_mv |
Grundmann, Hajo Glasner, Corinna Albiger, Barbara Aanensen, David M. Tomlinson, Chris T. Andrasević, Arjana Tambić Cantón, Rafael Carmeli, Yehuda Friedrich, Alexander W. Giske, Christian G. Glupczynski, Youri Gniadkowski, Marek Livermore, David M. Nordmann, Patrice Poirel, Laurent Rossolini, Gian M. Seifert, Harald Vatopoulos, Alkiviadis Walsh, Timothy Woodford, Neil Monnet, Dominique L. EuSCAPE Working Group Koraqi, A.. Lacej, D. Apfalter, P. Hartl, R. Glupczynski, Y. Huang, T.D. Strateva, T Marteva-Proevska, Y. Tambic, Andrasevic A. Butic, I. Pieridou-Bagatzouni, D. Maikanti-Charalampous, P. Hrabak, J. Zemlickova, H. Hammerum, A. Jakobsen, L. Ivanova, M. Pavelkovich, A. Jalava, J. Österblad, M. Dortet, L. Vaux, S. Kaase, M. Gatermann, S.G. Vatopoulos, A. Tryfinopoulou, K. Tóth, A. Jánvári, L. Boo, T.W. McGrath, E. Carmeli, Y. Adler, A. Pantosti, A. Monaco, M. Raka, L. Kurti, A. Balode, A. Saule, M. Miciuleviciene, J. Mierauskaite, A. Perrin -Weniger, M. Reichert, P. Nestorova, N. Debattista, S. Mijovic, G. Lopicic, M. Samuelsen, Ø. Haldorsen, B.J. Żabicka, D. Literacka, E. Caniça, M. Manageiro, V. Kaftandzieva, A. Trajkovska-Dokic, E. Damian, M. Lixandru, B. Jelesic, Z. Trudic, A. Niks, M. Schreterova, E. Pirs, M. Cerar, T. Oteo, J. Aracil, B. Giske, C. Sjöström, K. Gür, D. Cakar, A. Woodford, N. Hopkins, K. Wiuff, C. Brown, D.J. |
dc.subject.por.fl_str_mv |
EuSCAPE ECDC Carbapenemase-producing Klebsiella pneumoniae Carbapenemase-producing Escherichia coli Resistência aos Antimicrobianos |
topic |
EuSCAPE ECDC Carbapenemase-producing Klebsiella pneumoniae Carbapenemase-producing Escherichia coli Resistência aos Antimicrobianos |
description |
The members of the European Survey on Carbapenemase-Producing Enterobacteriaceae, (EuSCAPE) Working Group are: Portugal—Manuela Caniça and Vera Manageiro |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-11-19T01:30:14Z 2017-02 2017-02-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.18/4250 |
url |
http://hdl.handle.net/10400.18/4250 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Lancet Infect Dis. 2017 Feb;17(2):153-163. doi: 10.1016/S1473-3099(16)30257-2. Epub 2016 Nov 18. 1473-3099 10.1016/S1473-3099(16)30257-2 |
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info:eu-repo/semantics/embargoedAccess |
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embargoedAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier: Lancet |
publisher.none.fl_str_mv |
Elsevier: Lancet |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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