Poroelastic Modeling of Highly Hydrated Collagen Hydrogels: Experimental Results vs. Numerical Simulation With Custom and Commercial Finite Element Solvers
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10884/1491 |
Resumo: | This study presents a comparison between the performances of two Finite Element (FE) solvers for the modeling of the poroelastic behavior of highly hydrated collagen hydrogels. Characterization of collagen hydrogels has been a widespread challenge since this is one of the most used natural biomaterials for Tissue Engineering (TE) applications. V-Biomech® is a free custom FE solver oriented to soft tissue modeling, while Abaqus® is a general-purpose commercial FE package which is widely used for biomechanics computational modeling. Poroelastic simulations with both solvers were compared to two experimental protocols performed by Busby et al. (2013) and Chandran and Barocas (2004), also using different implementations of the frequently used Neo-Hookean hyperelastic model. The average differences between solvers outputs were under 5% throughout the different tests and hydrogel properties. Thus, differences were small enough to be considered negligible and within the variability found experimentally from one sample to another. This work demonstrates that constitutive modeling of soft tissues, such as collagen hydrogels can be achieved with either V-Biomech or Abaqus standard options (without user-subroutine), which is important for the biomechanics and biomaterials research community. V-Biomech has shown its potential for the validation of biomechanical characterization of soft tissues, while Abaqus' versatility is useful for the modeling and analysis of TE applications where other complex phenomena may also need to be captured. |
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Poroelastic Modeling of Highly Hydrated Collagen Hydrogels: Experimental Results vs. Numerical Simulation With Custom and Commercial Finite Element SolversBiomechanicsBiomaterialsbiomedical engineering,soft tissues,collagenfinite element solversThis study presents a comparison between the performances of two Finite Element (FE) solvers for the modeling of the poroelastic behavior of highly hydrated collagen hydrogels. Characterization of collagen hydrogels has been a widespread challenge since this is one of the most used natural biomaterials for Tissue Engineering (TE) applications. V-Biomech® is a free custom FE solver oriented to soft tissue modeling, while Abaqus® is a general-purpose commercial FE package which is widely used for biomechanics computational modeling. Poroelastic simulations with both solvers were compared to two experimental protocols performed by Busby et al. (2013) and Chandran and Barocas (2004), also using different implementations of the frequently used Neo-Hookean hyperelastic model. The average differences between solvers outputs were under 5% throughout the different tests and hydrogel properties. Thus, differences were small enough to be considered negligible and within the variability found experimentally from one sample to another. This work demonstrates that constitutive modeling of soft tissues, such as collagen hydrogels can be achieved with either V-Biomech or Abaqus standard options (without user-subroutine), which is important for the biomechanics and biomaterials research community. V-Biomech has shown its potential for the validation of biomechanical characterization of soft tissues, while Abaqus' versatility is useful for the modeling and analysis of TE applications where other complex phenomena may also need to be captured.Frontiers of Bioengineering and Biotechnology2021-05-11T13:33:44Z2018-10-01T00:00:00Z2018-10info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10884/1491engCastro, André P. G.Yao, JiangBattisti, TomLacroix, Damieninfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-04T11:08:15Zoai:repositorio-cientifico.uatlantica.pt:10884/1491Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:29:59.370535Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Poroelastic Modeling of Highly Hydrated Collagen Hydrogels: Experimental Results vs. Numerical Simulation With Custom and Commercial Finite Element Solvers |
title |
Poroelastic Modeling of Highly Hydrated Collagen Hydrogels: Experimental Results vs. Numerical Simulation With Custom and Commercial Finite Element Solvers |
spellingShingle |
Poroelastic Modeling of Highly Hydrated Collagen Hydrogels: Experimental Results vs. Numerical Simulation With Custom and Commercial Finite Element Solvers Castro, André P. G. Biomechanics Biomaterials biomedical engineering, soft tissues, collagen finite element solvers |
title_short |
Poroelastic Modeling of Highly Hydrated Collagen Hydrogels: Experimental Results vs. Numerical Simulation With Custom and Commercial Finite Element Solvers |
title_full |
Poroelastic Modeling of Highly Hydrated Collagen Hydrogels: Experimental Results vs. Numerical Simulation With Custom and Commercial Finite Element Solvers |
title_fullStr |
Poroelastic Modeling of Highly Hydrated Collagen Hydrogels: Experimental Results vs. Numerical Simulation With Custom and Commercial Finite Element Solvers |
title_full_unstemmed |
Poroelastic Modeling of Highly Hydrated Collagen Hydrogels: Experimental Results vs. Numerical Simulation With Custom and Commercial Finite Element Solvers |
title_sort |
Poroelastic Modeling of Highly Hydrated Collagen Hydrogels: Experimental Results vs. Numerical Simulation With Custom and Commercial Finite Element Solvers |
author |
Castro, André P. G. |
author_facet |
Castro, André P. G. Yao, Jiang Battisti, Tom Lacroix, Damien |
author_role |
author |
author2 |
Yao, Jiang Battisti, Tom Lacroix, Damien |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Castro, André P. G. Yao, Jiang Battisti, Tom Lacroix, Damien |
dc.subject.por.fl_str_mv |
Biomechanics Biomaterials biomedical engineering, soft tissues, collagen finite element solvers |
topic |
Biomechanics Biomaterials biomedical engineering, soft tissues, collagen finite element solvers |
description |
This study presents a comparison between the performances of two Finite Element (FE) solvers for the modeling of the poroelastic behavior of highly hydrated collagen hydrogels. Characterization of collagen hydrogels has been a widespread challenge since this is one of the most used natural biomaterials for Tissue Engineering (TE) applications. V-Biomech® is a free custom FE solver oriented to soft tissue modeling, while Abaqus® is a general-purpose commercial FE package which is widely used for biomechanics computational modeling. Poroelastic simulations with both solvers were compared to two experimental protocols performed by Busby et al. (2013) and Chandran and Barocas (2004), also using different implementations of the frequently used Neo-Hookean hyperelastic model. The average differences between solvers outputs were under 5% throughout the different tests and hydrogel properties. Thus, differences were small enough to be considered negligible and within the variability found experimentally from one sample to another. This work demonstrates that constitutive modeling of soft tissues, such as collagen hydrogels can be achieved with either V-Biomech or Abaqus standard options (without user-subroutine), which is important for the biomechanics and biomaterials research community. V-Biomech has shown its potential for the validation of biomechanical characterization of soft tissues, while Abaqus' versatility is useful for the modeling and analysis of TE applications where other complex phenomena may also need to be captured. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-10-01T00:00:00Z 2018-10 2021-05-11T13:33:44Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10884/1491 |
url |
http://hdl.handle.net/10884/1491 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Frontiers of Bioengineering and Biotechnology |
publisher.none.fl_str_mv |
Frontiers of Bioengineering and Biotechnology |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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