It comes from the sea: macroalgae-derived bioactive compounds with anti-cancer potential

Detalhes bibliográficos
Autor(a) principal: Nova, Paulo
Data de Publicação: 2023
Outros Autores: Gomes, Ana Maria, Costa-Pinto, Ana R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.14/41186
Resumo: Nature derived compounds represent a valuable source of bioactive molecules with enormous potential. The sea is one of the richest environments, full of skilled organisms, where algae stand out due to their unique characteristics. Marine macroalgae adapt their phenotypic characteristics, such as chemical composition, depending on the environmental conditions where they live. The compounds produced by these organisms show tremendous potential to be used in the biomedical field, due to their antioxidant, anti-inflammatory, immunomodulatory, and anti-cancer properties. Cancer is one of the deadliest diseases in the world, and the lack of effective treatments highlights the urgent need for the development of new therapeutic strategies. This review provides an overview of the current advances regarding the anti-cancer activity of the three major groups of marine macroalgae, i.e., red algae (Rhodophyta), brown algae (Phaeophyceae), and green algae (Chlorophyta) on pancreatic, lung, breast, cervical, colorectal, liver, and gastric cancers as well as leukemia and melanoma. In addition, future perspectives, and limitations regarding this field of work are also discussed.
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spelling It comes from the sea: macroalgae-derived bioactive compounds with anti-cancer potentialAlgaeBioactive compoundsCancerDrug discoveryMarine macroalgaeMolecular targetNature derived compounds represent a valuable source of bioactive molecules with enormous potential. The sea is one of the richest environments, full of skilled organisms, where algae stand out due to their unique characteristics. Marine macroalgae adapt their phenotypic characteristics, such as chemical composition, depending on the environmental conditions where they live. The compounds produced by these organisms show tremendous potential to be used in the biomedical field, due to their antioxidant, anti-inflammatory, immunomodulatory, and anti-cancer properties. Cancer is one of the deadliest diseases in the world, and the lack of effective treatments highlights the urgent need for the development of new therapeutic strategies. This review provides an overview of the current advances regarding the anti-cancer activity of the three major groups of marine macroalgae, i.e., red algae (Rhodophyta), brown algae (Phaeophyceae), and green algae (Chlorophyta) on pancreatic, lung, breast, cervical, colorectal, liver, and gastric cancers as well as leukemia and melanoma. In addition, future perspectives, and limitations regarding this field of work are also discussed.Veritati - Repositório Institucional da Universidade Católica PortuguesaNova, PauloGomes, Ana MariaCosta-Pinto, Ana R.2023-05-19T15:27:33Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.14/41186eng0738-855110.1080/07388551.2023.21740688514929570136842998000940449700001info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-12T17:46:46Zoai:repositorio.ucp.pt:10400.14/41186Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:33:51.461093Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv It comes from the sea: macroalgae-derived bioactive compounds with anti-cancer potential
title It comes from the sea: macroalgae-derived bioactive compounds with anti-cancer potential
spellingShingle It comes from the sea: macroalgae-derived bioactive compounds with anti-cancer potential
Nova, Paulo
Algae
Bioactive compounds
Cancer
Drug discovery
Marine macroalgae
Molecular target
title_short It comes from the sea: macroalgae-derived bioactive compounds with anti-cancer potential
title_full It comes from the sea: macroalgae-derived bioactive compounds with anti-cancer potential
title_fullStr It comes from the sea: macroalgae-derived bioactive compounds with anti-cancer potential
title_full_unstemmed It comes from the sea: macroalgae-derived bioactive compounds with anti-cancer potential
title_sort It comes from the sea: macroalgae-derived bioactive compounds with anti-cancer potential
author Nova, Paulo
author_facet Nova, Paulo
Gomes, Ana Maria
Costa-Pinto, Ana R.
author_role author
author2 Gomes, Ana Maria
Costa-Pinto, Ana R.
author2_role author
author
dc.contributor.none.fl_str_mv Veritati - Repositório Institucional da Universidade Católica Portuguesa
dc.contributor.author.fl_str_mv Nova, Paulo
Gomes, Ana Maria
Costa-Pinto, Ana R.
dc.subject.por.fl_str_mv Algae
Bioactive compounds
Cancer
Drug discovery
Marine macroalgae
Molecular target
topic Algae
Bioactive compounds
Cancer
Drug discovery
Marine macroalgae
Molecular target
description Nature derived compounds represent a valuable source of bioactive molecules with enormous potential. The sea is one of the richest environments, full of skilled organisms, where algae stand out due to their unique characteristics. Marine macroalgae adapt their phenotypic characteristics, such as chemical composition, depending on the environmental conditions where they live. The compounds produced by these organisms show tremendous potential to be used in the biomedical field, due to their antioxidant, anti-inflammatory, immunomodulatory, and anti-cancer properties. Cancer is one of the deadliest diseases in the world, and the lack of effective treatments highlights the urgent need for the development of new therapeutic strategies. This review provides an overview of the current advances regarding the anti-cancer activity of the three major groups of marine macroalgae, i.e., red algae (Rhodophyta), brown algae (Phaeophyceae), and green algae (Chlorophyta) on pancreatic, lung, breast, cervical, colorectal, liver, and gastric cancers as well as leukemia and melanoma. In addition, future perspectives, and limitations regarding this field of work are also discussed.
publishDate 2023
dc.date.none.fl_str_mv 2023-05-19T15:27:33Z
2023
2023-01-01T00:00:00Z
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10.1080/07388551.2023.2174068
85149295701
36842998
000940449700001
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