Epstein-Barr Virus-Associated Acute Interstitial Nephritis

Detalhes bibliográficos
Autor(a) principal: Luís, Telma
Data de Publicação: 2022
Outros Autores: Marinhas, Andreia, Neves, Catarina, Carmo, Carmen, Gomes, Clara
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25754/pjp.2022.25277
Resumo: Epstein-Barr virus (EBV) infection is usually asymptomatic in childhood, but acute kidney injury (AKI) may be a rare complication during its course. We report a case of a 5-year-old female presented with fever, vomiting, abdominal pain, anorexia, anemia, thrombocytopenia and acute oliguric renal failure with titer-confirmed EBV infection. Renal biopsy specimen revealed an acute interstitial nephritis (AIN) and endocapillary glomerulonephritis with EBV inclusions in renal tubules epithelium. Methylprednisolone pulse therapy was performed, followed by oral corticoid therapy. Hemodialysis was required for 10 days with renal function complete recovery in 17 days. Physicians should be alert of uncommon presentations of EBV infection in children and consider this differential diagnosis when facing AKI.
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spelling Epstein-Barr Virus-Associated Acute Interstitial NephritisCase reportsEpstein-Barr virus (EBV) infection is usually asymptomatic in childhood, but acute kidney injury (AKI) may be a rare complication during its course. We report a case of a 5-year-old female presented with fever, vomiting, abdominal pain, anorexia, anemia, thrombocytopenia and acute oliguric renal failure with titer-confirmed EBV infection. Renal biopsy specimen revealed an acute interstitial nephritis (AIN) and endocapillary glomerulonephritis with EBV inclusions in renal tubules epithelium. Methylprednisolone pulse therapy was performed, followed by oral corticoid therapy. Hemodialysis was required for 10 days with renal function complete recovery in 17 days. Physicians should be alert of uncommon presentations of EBV infection in children and consider this differential diagnosis when facing AKI.Sociedade Portuguesa de Pediatria2022-12-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25754/pjp.2022.25277eng2184-44532184-3333Luís, TelmaMarinhas, AndreiaNeves, CatarinaCarmo, CarmenGomes, Clarainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T02:58:22Zoai:ojs.revistas.rcaap.pt:article/25277Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:25:39.344711Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Epstein-Barr Virus-Associated Acute Interstitial Nephritis
title Epstein-Barr Virus-Associated Acute Interstitial Nephritis
spellingShingle Epstein-Barr Virus-Associated Acute Interstitial Nephritis
Luís, Telma
Case reports
title_short Epstein-Barr Virus-Associated Acute Interstitial Nephritis
title_full Epstein-Barr Virus-Associated Acute Interstitial Nephritis
title_fullStr Epstein-Barr Virus-Associated Acute Interstitial Nephritis
title_full_unstemmed Epstein-Barr Virus-Associated Acute Interstitial Nephritis
title_sort Epstein-Barr Virus-Associated Acute Interstitial Nephritis
author Luís, Telma
author_facet Luís, Telma
Marinhas, Andreia
Neves, Catarina
Carmo, Carmen
Gomes, Clara
author_role author
author2 Marinhas, Andreia
Neves, Catarina
Carmo, Carmen
Gomes, Clara
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Luís, Telma
Marinhas, Andreia
Neves, Catarina
Carmo, Carmen
Gomes, Clara
dc.subject.por.fl_str_mv Case reports
topic Case reports
description Epstein-Barr virus (EBV) infection is usually asymptomatic in childhood, but acute kidney injury (AKI) may be a rare complication during its course. We report a case of a 5-year-old female presented with fever, vomiting, abdominal pain, anorexia, anemia, thrombocytopenia and acute oliguric renal failure with titer-confirmed EBV infection. Renal biopsy specimen revealed an acute interstitial nephritis (AIN) and endocapillary glomerulonephritis with EBV inclusions in renal tubules epithelium. Methylprednisolone pulse therapy was performed, followed by oral corticoid therapy. Hemodialysis was required for 10 days with renal function complete recovery in 17 days. Physicians should be alert of uncommon presentations of EBV infection in children and consider this differential diagnosis when facing AKI.
publishDate 2022
dc.date.none.fl_str_mv 2022-12-12
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.25754/pjp.2022.25277
url https://doi.org/10.25754/pjp.2022.25277
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2184-4453
2184-3333
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Pediatria
publisher.none.fl_str_mv Sociedade Portuguesa de Pediatria
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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