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spelling A pilot study on the feasibility of European harmonized Human Biomonitoring : strategies towards a common approach, challenges and opportunitiesHuman biomonitoringEnvironmental health policyEuropean harmonizationEthicsStudy protocol© 2014 Elsevier Inc. All rights reserved.In 2004 the European Commission and Member States initiated activities towards a harmonized approach for Human Biomonitoring surveys throughout Europe. The main bjective was to sustain environmental health policy by building a coherent and sustainable framework and by increasing the comparability of data across countries. A pilot study to test common guidelines for setting up surveys was considered a key step in this process. Through a bottom-up approach that included all stakeholders, a joint study protocol was elaborated. From September 2011 till February 2012, 17 European countries collected data from 1844 mother–child pairs in the frame of DEMOnstration of a study to COordinate and Perform Human Biomonitoring on a European Scale (DEMOCOPHES).1 Mercury in hair and urinary cadmium and cotinine were selected as biomarkers of exposure covered by sufficient analytical experience. Phthalate metabolites and Bisphenol A in urine were added to take into account increasing public and political awareness for emerging types of contaminants and to test less advanced markers/markers covered by less analytical experience. Extensive efforts towards chemo-analytical comparability were included. The pilot study showed that common approaches can be found in a context of considerable differences with respect to experience and expertize, socio-cultural background, economic situation and national priorities. It also evidenced that comparable Human Biomonitoring results can be obtained in such context. A European network was built, exchanging information, expertize and experiences, and providing training on all aspects of a survey. A key challenge was finding the right balance between a rigid structure allowing maximal comparability and a flexible approach increasing feasibility and capacity building. Next steps in European harmonization in Human Biomonitoring surveys include the establishment of a joint process for prioritization of substances to cover and biomarkers to develop, linking biomonitoring surveys with health examination surveys and with research, and coping with the diverse implementations of EU regulations and international guidelines with respect to ethics and privacy.Financial support: COPHES (COnsortium to Perform Human Biomonitoring on a European Scale) was funded by the Seventh EU Framework Programme 2007–2011 under grant agreement no [244237]. DEMOCOPHES (DEMOnstration of a study to COordinate and Perform Human Biomonitoring on a European Scale) was co-funded (50%:50%) by the European Commission LIFE+ Programme (LIFE09/ENV/BE/000410) and the partners.ElsevierRepositório da Universidade de LisboaCasteleyn, L.Dumez, B.Becker, K.Kolossa-Gehring, M.Den Hond, E.Schoeters, G.Castaño, A.Koch, H. M.Angerer, J.Esteban, M.Exley, K.Sepai, O.Bloemen, L.Horvat, M.Knudsen, L. E.Joas, A.Joas, R.Biot, P.Koppen, G.Dewolf, M-C.Katsonouri, K.Hadjipanayis, A.Cerná, M.Krsková, A.Schwedler, G.Fiddicke, U.Nielsen, J. K. S.Jensen, J. F.Rudnai, P.Közepésy, S.Mulcahy, M.Mannion, R.Gutleb, A. C.Fischer, M. E.Ligocka, D.Jakubowski, M.Reis, M. F.Namorado, S.Lupsa, I-R.Gurzau, A. E.Halzlova, K.Jajcaj, M.Mazej, D.Snoj, J. TratnikPosada, M.López, E.Berglund, M.Larsson, K.Lehmann, A.Crettaz, P.Aerts, D.2015-03-10T15:25:36Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/17689engEnviron. Res. (2015)0013-9351http://dx.doi.org/10.1016/j.envres.2014.10.028metadata only accessinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:03:26Zoai:repositorio.ul.pt:10451/17689Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:37:28.614387Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A pilot study on the feasibility of European harmonized Human Biomonitoring : strategies towards a common approach, challenges and opportunities
title A pilot study on the feasibility of European harmonized Human Biomonitoring : strategies towards a common approach, challenges and opportunities
spellingShingle A pilot study on the feasibility of European harmonized Human Biomonitoring : strategies towards a common approach, challenges and opportunities
Casteleyn, L.
Human biomonitoring
Environmental health policy
European harmonization
Ethics
Study protocol
title_short A pilot study on the feasibility of European harmonized Human Biomonitoring : strategies towards a common approach, challenges and opportunities
title_full A pilot study on the feasibility of European harmonized Human Biomonitoring : strategies towards a common approach, challenges and opportunities
title_fullStr A pilot study on the feasibility of European harmonized Human Biomonitoring : strategies towards a common approach, challenges and opportunities
title_full_unstemmed A pilot study on the feasibility of European harmonized Human Biomonitoring : strategies towards a common approach, challenges and opportunities
title_sort A pilot study on the feasibility of European harmonized Human Biomonitoring : strategies towards a common approach, challenges and opportunities
author Casteleyn, L.
author_facet Casteleyn, L.
Dumez, B.
Becker, K.
Kolossa-Gehring, M.
Den Hond, E.
Schoeters, G.
Castaño, A.
Koch, H. M.
Angerer, J.
Esteban, M.
Exley, K.
Sepai, O.
Bloemen, L.
Horvat, M.
Knudsen, L. E.
Joas, A.
Joas, R.
Biot, P.
Koppen, G.
Dewolf, M-C.
Katsonouri, K.
Hadjipanayis, A.
Cerná, M.
Krsková, A.
Schwedler, G.
Fiddicke, U.
Nielsen, J. K. S.
Jensen, J. F.
Rudnai, P.
Közepésy, S.
Mulcahy, M.
Mannion, R.
Gutleb, A. C.
Fischer, M. E.
Ligocka, D.
Jakubowski, M.
Reis, M. F.
Namorado, S.
Lupsa, I-R.
Gurzau, A. E.
Halzlova, K.
Jajcaj, M.
Mazej, D.
Snoj, J. Tratnik
Posada, M.
López, E.
Berglund, M.
Larsson, K.
Lehmann, A.
Crettaz, P.
Aerts, D.
author_role author
author2 Dumez, B.
Becker, K.
Kolossa-Gehring, M.
Den Hond, E.
Schoeters, G.
Castaño, A.
Koch, H. M.
Angerer, J.
Esteban, M.
Exley, K.
Sepai, O.
Bloemen, L.
Horvat, M.
Knudsen, L. E.
Joas, A.
Joas, R.
Biot, P.
Koppen, G.
Dewolf, M-C.
Katsonouri, K.
Hadjipanayis, A.
Cerná, M.
Krsková, A.
Schwedler, G.
Fiddicke, U.
Nielsen, J. K. S.
Jensen, J. F.
Rudnai, P.
Közepésy, S.
Mulcahy, M.
Mannion, R.
Gutleb, A. C.
Fischer, M. E.
Ligocka, D.
Jakubowski, M.
Reis, M. F.
Namorado, S.
Lupsa, I-R.
Gurzau, A. E.
Halzlova, K.
Jajcaj, M.
Mazej, D.
Snoj, J. Tratnik
Posada, M.
López, E.
Berglund, M.
Larsson, K.
Lehmann, A.
Crettaz, P.
Aerts, D.
author2_role author
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dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Casteleyn, L.
Dumez, B.
Becker, K.
Kolossa-Gehring, M.
Den Hond, E.
Schoeters, G.
Castaño, A.
Koch, H. M.
Angerer, J.
Esteban, M.
Exley, K.
Sepai, O.
Bloemen, L.
Horvat, M.
Knudsen, L. E.
Joas, A.
Joas, R.
Biot, P.
Koppen, G.
Dewolf, M-C.
Katsonouri, K.
Hadjipanayis, A.
Cerná, M.
Krsková, A.
Schwedler, G.
Fiddicke, U.
Nielsen, J. K. S.
Jensen, J. F.
Rudnai, P.
Közepésy, S.
Mulcahy, M.
Mannion, R.
Gutleb, A. C.
Fischer, M. E.
Ligocka, D.
Jakubowski, M.
Reis, M. F.
Namorado, S.
Lupsa, I-R.
Gurzau, A. E.
Halzlova, K.
Jajcaj, M.
Mazej, D.
Snoj, J. Tratnik
Posada, M.
López, E.
Berglund, M.
Larsson, K.
Lehmann, A.
Crettaz, P.
Aerts, D.
dc.subject.por.fl_str_mv Human biomonitoring
Environmental health policy
European harmonization
Ethics
Study protocol
topic Human biomonitoring
Environmental health policy
European harmonization
Ethics
Study protocol
description © 2014 Elsevier Inc. All rights reserved.
publishDate 2015
dc.date.none.fl_str_mv 2015-03-10T15:25:36Z
2015
2015-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/17689
url http://hdl.handle.net/10451/17689
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Environ. Res. (2015)
0013-9351
http://dx.doi.org/10.1016/j.envres.2014.10.028
dc.rights.driver.fl_str_mv metadata only access
info:eu-repo/semantics/openAccess
rights_invalid_str_mv metadata only access
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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