Fluid extraction from the left-right organizer uncovers mechanical properties needed for symmetry breaking

• Autor(a) principal: Sampaio, Pedro
• Data de Publicação: 2023
• Outros Autores: Pestana, Sara, Bota, Catarina, Guerrero, Adán, Telley, Ivo A., Smith, David, Lopes, Susana Santos
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/10362/157776
• topic: Neuroscience(all); Biochemistry, Genetics and Molecular Biology(all); Immunology and Microbiology(all)

Funding Information: This work was mainly supported by the Fundação para a Ciência e Tecnologia (research grant – PTDC/ BEX-BID/1411/2014). Funding Information: PS was funded by a PhD fellowship FCT: SFRH/BD/111611/2015. SP was funded by a PhD fellowship FCT: SFRH/BD/130272/2017 CB was funded by a PhD fellowship FCT: SFRH/BD/141034/2018 IAT was funded by FCT Investigator IF/00082/2013, EU FP7-PEOPLE-2013-CIG (N° 818743) and by the Fundação Calouste Gulbenkian (FCG). AG thanks to CZI Expanding Global Access to Bioimaging and to PAPIIT (IN211821) for funding support. DJS acknowledges support from the Engineering and Physical Sciences Research Council UK via a Healthcare Technologies Challenge Award (EP/N021096/1) and a Turing Fellowship (EP/N510129/1). SL was funded by FCT Investigator IF/00951/2012, by NOVA Medical School and by FCT CEEC-IND 2018. Zebrafish were reared and maintained in the NMS Fish Facility, with the support from the research consortia Congento funded by LISBOA-01–0145-FEDER-022170, microscopy was performed at the IGC Advanced Imaging Facility which is supported by PPBI-POCI-01–0145-FEDER-022122; all co-financed by Lisboa Regional Operational Program (Lisboa2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (ERDF) and Fundação para a Ciência e Tecnologia under the project. The project LysoCil funded by the European Union Horizon 2020 research and innovation under grant agreement No 811087 supported SL, PS and SP travelling to the FASEB cilia meeting in the USA in 2019, where this work was presented and discussed with peers. We thank Sérgio Dias for reviewing the final version of the manuscript. Publisher Copyright: © Sampaio, Pestana et al.