Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese patients

Detalhes bibliográficos
Autor(a) principal: Rosa, A.
Data de Publicação: 2008
Outros Autores: Fonseca, B.V., Krug, T., Manso, H., Gouveia, L., Albergaria, I., Gaspar, G., Correia, M., Viana-Baptista, M., Simões, R.M., Pinto, A.N., Taipa, R., Ferreira, C., Fontes, J.R., Silva, M.R., Gabriel, J.P., Matos, I., Lopes, G., Ferro, J.M., Vicente, A.M., Oliveira, S.A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/330
Resumo: The genetic contribution to stroke is well established but it has proven difficult to identify the genes and the disease-associated alleles mediating this effect, possibly because only nuclear genes have been intensely investigated so far. Mitochondrial DNA (mtDNA) has been implicated in several disorders having stroke as one of its clinical manifestations. The aim of this case-control study was to assess the contribution of mtDNA polymorphisms and haplogroups to ischemic stroke risk.
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spelling Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese patientsDoenças Cardio e Cérebro-vascularesThe genetic contribution to stroke is well established but it has proven difficult to identify the genes and the disease-associated alleles mediating this effect, possibly because only nuclear genes have been intensely investigated so far. Mitochondrial DNA (mtDNA) has been implicated in several disorders having stroke as one of its clinical manifestations. The aim of this case-control study was to assess the contribution of mtDNA polymorphisms and haplogroups to ischemic stroke risk.BioMed CentralRepositório Científico do Instituto Nacional de SaúdeRosa, A.Fonseca, B.V.Krug, T.Manso, H.Gouveia, L.Albergaria, I.Gaspar, G.Correia, M.Viana-Baptista, M.Simões, R.M.Pinto, A.N.Taipa, R.Ferreira, C.Fontes, J.R.Silva, M.R.Gabriel, J.P.Matos, I.Lopes, G.Ferro, J.M.Vicente, A.M.Oliveira, S.A.2011-11-30T17:20:04Z2008-07-012008-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/330engBMC Med Genet. 2008 Jul 1;9:571471-2350doi:10.1186/1471-2350-9-57info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:38:08Zoai:repositorio.insa.pt:10400.18/330Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:35:33.077486Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese patients
title Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese patients
spellingShingle Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese patients
Rosa, A.
Doenças Cardio e Cérebro-vasculares
title_short Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese patients
title_full Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese patients
title_fullStr Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese patients
title_full_unstemmed Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese patients
title_sort Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese patients
author Rosa, A.
author_facet Rosa, A.
Fonseca, B.V.
Krug, T.
Manso, H.
Gouveia, L.
Albergaria, I.
Gaspar, G.
Correia, M.
Viana-Baptista, M.
Simões, R.M.
Pinto, A.N.
Taipa, R.
Ferreira, C.
Fontes, J.R.
Silva, M.R.
Gabriel, J.P.
Matos, I.
Lopes, G.
Ferro, J.M.
Vicente, A.M.
Oliveira, S.A.
author_role author
author2 Fonseca, B.V.
Krug, T.
Manso, H.
Gouveia, L.
Albergaria, I.
Gaspar, G.
Correia, M.
Viana-Baptista, M.
Simões, R.M.
Pinto, A.N.
Taipa, R.
Ferreira, C.
Fontes, J.R.
Silva, M.R.
Gabriel, J.P.
Matos, I.
Lopes, G.
Ferro, J.M.
Vicente, A.M.
Oliveira, S.A.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Rosa, A.
Fonseca, B.V.
Krug, T.
Manso, H.
Gouveia, L.
Albergaria, I.
Gaspar, G.
Correia, M.
Viana-Baptista, M.
Simões, R.M.
Pinto, A.N.
Taipa, R.
Ferreira, C.
Fontes, J.R.
Silva, M.R.
Gabriel, J.P.
Matos, I.
Lopes, G.
Ferro, J.M.
Vicente, A.M.
Oliveira, S.A.
dc.subject.por.fl_str_mv Doenças Cardio e Cérebro-vasculares
topic Doenças Cardio e Cérebro-vasculares
description The genetic contribution to stroke is well established but it has proven difficult to identify the genes and the disease-associated alleles mediating this effect, possibly because only nuclear genes have been intensely investigated so far. Mitochondrial DNA (mtDNA) has been implicated in several disorders having stroke as one of its clinical manifestations. The aim of this case-control study was to assess the contribution of mtDNA polymorphisms and haplogroups to ischemic stroke risk.
publishDate 2008
dc.date.none.fl_str_mv 2008-07-01
2008-07-01T00:00:00Z
2011-11-30T17:20:04Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/330
url http://hdl.handle.net/10400.18/330
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv BMC Med Genet. 2008 Jul 1;9:57
1471-2350
doi:10.1186/1471-2350-9-57
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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