Interpreting biomarker data from the COPHES/DEMOCOPHES twin projects : using external exposure data to understand biomarker differences among countries
| Autor(a) principal: | |
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| Data de Publicação: | 2014 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10451/15331 |
Resumo: | © 2014 Elsevier Inc. All rights reserved. |
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Interpreting biomarker data from the COPHES/DEMOCOPHES twin projects : using external exposure data to understand biomarker differences among countriesHuman biomonitoringInterpretationCOPHES/DEMOCOPHESExternal exposure data© 2014 Elsevier Inc. All rights reserved.In 2011 and 2012,the COPHES/DEMOCOPHES twin projects performedt he first ever harmonized human biomonitoring survey in 17 European countries.In more than 1800 mother–child pairs,individual lifestyle data were collected and cadmium,cotinine and certain phthalate metabolites were measured in urine. Total mercury was determined in hair samples.While the main goal of the COPHES/DEMOCOPHES twin projects was to develop and test harmonized protocols and procedures,the goal of the current paper is to investigate whether the observed differences in biomarker values among the countries implementing DEMOCOPHES can be interpreted using information from external databases on environmental quality and lifestyle.In general,13 countries having implemented DEMOCOPHES provided high quality data from external sources that were relevant for interpretation purposes.However,some data were not available for reporting or were not in line with predefined specifications. Therefore,only part of the external information could be included in the statistical analyses. Nonetheless,there was a highly significant correlation between national levels of fish consumption and mercury in hair,the strength of antismoking legislation was significantly related to urinary cotinine levels,and we were able to show indications that also urinary cadmium levels were associated with environmental quality and food quality.These results again show the potential of biomonitoring data to provide added value for(the evaluation of)evidence-informed policy making.The European Commission,Belgium,DG for Research and Innovation(RTD),who is funding COPHES in the 7th Framework Programme(No.244237).DEMOCOPHES(LIFE09ENV/BE/000410)received 50% funding through the LIFE+ financial instrument of the European Union(DGENV),as well as 50% through funding received from the DEMOCOPHES partners.ElsevierRepositório da Universidade de LisboaSmolders, R.Den Hond, E.Koppen, G.Govarts, E.Willems, H.Casteleyn, L.Kolossa-Gehring, M.Fiddicke, U.Castaño, A.Koch, H. M.Angerer, J.Esteban, M.Sepai, O.Exley, K.Bloemen, L.Horvat, M.Knudsen, L. E.Joas, A.Joas, R.Biot, P.Aerts, D.Katsonouri, A.Hadjipanayis, A.Cerna, M.Krskova, A.Schwedler, G.Seiwert, M.Nielsen, J. K. S.Rudnai, P.Közepesy, S.Evans, D. S.Ryan, M. P.Gutleb, A. C.Fischer, M. E.Ligocka, D.Jakubowski, M.Reis, M. F.Namorado, S.Lupsa, I. R.Gurzau, A. E.Halzlova, K.Fabianova, E.Mazej, D.Snoj, J. T.Gomez, S.González, S.Berglund, M.Larsson, K.Lehmann, A.Crettaz, P.Schoeters, G.2014-11-24T15:14:16Z20142014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/15331engEnviron. Res. (2014) http://dx.doi.org/10.1016/j.envres.2014.08.0160013-9351http://dx.doi.org/10.1016/j.envres.2014.08.016metadata only accessinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-11-20T17:20:56Zoai:repositorio.ul.pt:10451/15331Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-11-20T17:20:56Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Interpreting biomarker data from the COPHES/DEMOCOPHES twin projects : using external exposure data to understand biomarker differences among countries |
| title |
Interpreting biomarker data from the COPHES/DEMOCOPHES twin projects : using external exposure data to understand biomarker differences among countries |
| spellingShingle |
Interpreting biomarker data from the COPHES/DEMOCOPHES twin projects : using external exposure data to understand biomarker differences among countries Smolders, R. Human biomonitoring Interpretation COPHES/DEMOCOPHES External exposure data |
| title_short |
Interpreting biomarker data from the COPHES/DEMOCOPHES twin projects : using external exposure data to understand biomarker differences among countries |
| title_full |
Interpreting biomarker data from the COPHES/DEMOCOPHES twin projects : using external exposure data to understand biomarker differences among countries |
| title_fullStr |
Interpreting biomarker data from the COPHES/DEMOCOPHES twin projects : using external exposure data to understand biomarker differences among countries |
| title_full_unstemmed |
Interpreting biomarker data from the COPHES/DEMOCOPHES twin projects : using external exposure data to understand biomarker differences among countries |
| title_sort |
Interpreting biomarker data from the COPHES/DEMOCOPHES twin projects : using external exposure data to understand biomarker differences among countries |
| author |
Smolders, R. |
| author_facet |
Smolders, R. Den Hond, E. Koppen, G. Govarts, E. Willems, H. Casteleyn, L. Kolossa-Gehring, M. Fiddicke, U. Castaño, A. Koch, H. M. Angerer, J. Esteban, M. Sepai, O. Exley, K. Bloemen, L. Horvat, M. Knudsen, L. E. Joas, A. Joas, R. Biot, P. Aerts, D. Katsonouri, A. Hadjipanayis, A. Cerna, M. Krskova, A. Schwedler, G. Seiwert, M. Nielsen, J. K. S. Rudnai, P. Közepesy, S. Evans, D. S. Ryan, M. P. Gutleb, A. C. Fischer, M. E. Ligocka, D. Jakubowski, M. Reis, M. F. Namorado, S. Lupsa, I. R. Gurzau, A. E. Halzlova, K. Fabianova, E. Mazej, D. Snoj, J. T. Gomez, S. González, S. Berglund, M. Larsson, K. Lehmann, A. Crettaz, P. Schoeters, G. |
| author_role |
author |
| author2 |
Den Hond, E. Koppen, G. Govarts, E. Willems, H. Casteleyn, L. Kolossa-Gehring, M. Fiddicke, U. Castaño, A. Koch, H. M. Angerer, J. Esteban, M. Sepai, O. Exley, K. Bloemen, L. Horvat, M. Knudsen, L. E. Joas, A. Joas, R. Biot, P. Aerts, D. Katsonouri, A. Hadjipanayis, A. Cerna, M. Krskova, A. Schwedler, G. Seiwert, M. Nielsen, J. K. S. Rudnai, P. Közepesy, S. Evans, D. S. Ryan, M. P. Gutleb, A. C. Fischer, M. E. Ligocka, D. Jakubowski, M. Reis, M. F. Namorado, S. Lupsa, I. R. Gurzau, A. E. Halzlova, K. Fabianova, E. Mazej, D. Snoj, J. T. Gomez, S. González, S. Berglund, M. Larsson, K. Lehmann, A. Crettaz, P. Schoeters, G. |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
| dc.contributor.author.fl_str_mv |
Smolders, R. Den Hond, E. Koppen, G. Govarts, E. Willems, H. Casteleyn, L. Kolossa-Gehring, M. Fiddicke, U. Castaño, A. Koch, H. M. Angerer, J. Esteban, M. Sepai, O. Exley, K. Bloemen, L. Horvat, M. Knudsen, L. E. Joas, A. Joas, R. Biot, P. Aerts, D. Katsonouri, A. Hadjipanayis, A. Cerna, M. Krskova, A. Schwedler, G. Seiwert, M. Nielsen, J. K. S. Rudnai, P. Közepesy, S. Evans, D. S. Ryan, M. P. Gutleb, A. C. Fischer, M. E. Ligocka, D. Jakubowski, M. Reis, M. F. Namorado, S. Lupsa, I. R. Gurzau, A. E. Halzlova, K. Fabianova, E. Mazej, D. Snoj, J. T. Gomez, S. González, S. Berglund, M. Larsson, K. Lehmann, A. Crettaz, P. Schoeters, G. |
| dc.subject.por.fl_str_mv |
Human biomonitoring Interpretation COPHES/DEMOCOPHES External exposure data |
| topic |
Human biomonitoring Interpretation COPHES/DEMOCOPHES External exposure data |
| description |
© 2014 Elsevier Inc. All rights reserved. |
| publishDate |
2014 |
| dc.date.none.fl_str_mv |
2014-11-24T15:14:16Z 2014 2014-01-01T00:00:00Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10451/15331 |
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http://hdl.handle.net/10451/15331 |
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eng |
| language |
eng |
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Environ. Res. (2014) http://dx.doi.org/10.1016/j.envres.2014.08.016 0013-9351 http://dx.doi.org/10.1016/j.envres.2014.08.016 |
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metadata only access info:eu-repo/semantics/openAccess |
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metadata only access |
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application/pdf |
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Elsevier |
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Elsevier |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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mluisa.alvim@gmail.com |
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