Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://hdl.handle.net/10216/153781 |
Resumo: | Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use of plant-derived bioactive molecules for the treatment of autism. Among the plethora of bioactives, curcumin, luteolin, and resveratrol have revealed excellent neuroprotective effects and can be effectively used in the treatment of neuropsychological disorders. However, the number of clinical trials is limited, and none of them have been approved for the treatment of autism or autism-related disorder. Further clinical studies are needed to effectively assess the real potential of such bioactive molecules. |
id |
RCAP_30d913c8f21fe95191a7a4540e431d79 |
---|---|
oai_identifier_str |
oai:repositorio-aberto.up.pt:10216/153781 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum DisorderAutism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use of plant-derived bioactive molecules for the treatment of autism. Among the plethora of bioactives, curcumin, luteolin, and resveratrol have revealed excellent neuroprotective effects and can be effectively used in the treatment of neuropsychological disorders. However, the number of clinical trials is limited, and none of them have been approved for the treatment of autism or autism-related disorder. Further clinical studies are needed to effectively assess the real potential of such bioactive molecules.Hindawi20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10216/153781eng1942-090010.1155/2021/1131280Martins, NQuispe, CKirkin, CSenol, EZulug, AÖzçelik, BAdemiluyi, AOOyeniran, OHSemwal, PKumar, MSharopov, FLópez, VLes, FBagiu, ICButnariu, MSharifi-Rad, JAlshehri, MMCho, WCinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T15:32:37Zoai:repositorio-aberto.up.pt:10216/153781Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:26:09.553259Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder |
title |
Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder |
spellingShingle |
Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder Martins, N |
title_short |
Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder |
title_full |
Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder |
title_fullStr |
Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder |
title_full_unstemmed |
Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder |
title_sort |
Paving Plant-Food-Derived Bioactives as Effective Therapeutic Agents in Autism Spectrum Disorder |
author |
Martins, N |
author_facet |
Martins, N Quispe, C Kirkin, C Senol, E Zulug, A Özçelik, B Ademiluyi, AO Oyeniran, OH Semwal, P Kumar, M Sharopov, F López, V Les, F Bagiu, IC Butnariu, M Sharifi-Rad, J Alshehri, MM Cho, WC |
author_role |
author |
author2 |
Quispe, C Kirkin, C Senol, E Zulug, A Özçelik, B Ademiluyi, AO Oyeniran, OH Semwal, P Kumar, M Sharopov, F López, V Les, F Bagiu, IC Butnariu, M Sharifi-Rad, J Alshehri, MM Cho, WC |
author2_role |
author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Martins, N Quispe, C Kirkin, C Senol, E Zulug, A Özçelik, B Ademiluyi, AO Oyeniran, OH Semwal, P Kumar, M Sharopov, F López, V Les, F Bagiu, IC Butnariu, M Sharifi-Rad, J Alshehri, MM Cho, WC |
description |
Autism spectrum disorder (ASD) is a neurodevelopmental disorder, where social and communication deficits and repetitive behaviors are present. Plant-derived bioactives have shown promising results in the treatment of autism. In this sense, this review is aimed at providing a careful view on the use of plant-derived bioactive molecules for the treatment of autism. Among the plethora of bioactives, curcumin, luteolin, and resveratrol have revealed excellent neuroprotective effects and can be effectively used in the treatment of neuropsychological disorders. However, the number of clinical trials is limited, and none of them have been approved for the treatment of autism or autism-related disorder. Further clinical studies are needed to effectively assess the real potential of such bioactive molecules. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021 2021-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/10216/153781 |
url |
https://hdl.handle.net/10216/153781 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1942-0900 10.1155/2021/1131280 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hindawi |
publisher.none.fl_str_mv |
Hindawi |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799136175406972928 |