Injectable gellan gum-based hydrogels for intervertebral disc regeneration
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/12795 |
Resumo: | Intervertebral disc (IVD) degeneration is a challenging pathology that, due to the inefficiency of the current treatments, urgently demands for the development of new regenerative approaches[1]. The best viable implant material for nucleus pulposus (NP) regeneration has yet to be identified, but it is believed that biodegradable hydrogelbased materials are promising candidates[2]. In this work, we are proposing the use of ionic- and photocrosslinked methacrylated gellan gum (GG-MA) hydrogels as potential acellular and cellular injectable scaffolds for IVD regeneration. |
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Injectable gellan gum-based hydrogels for intervertebral disc regenerationGellan gumIntervertebralIntervertebral disc (IVD) degeneration is a challenging pathology that, due to the inefficiency of the current treatments, urgently demands for the development of new regenerative approaches[1]. The best viable implant material for nucleus pulposus (NP) regeneration has yet to be identified, but it is believed that biodegradable hydrogelbased materials are promising candidates[2]. In this work, we are proposing the use of ionic- and photocrosslinked methacrylated gellan gum (GG-MA) hydrogels as potential acellular and cellular injectable scaffolds for IVD regeneration.Universidade do MinhoSilva-Correia, JoanaOliveira, Joaquim M.Caridade, S. G.Oliveira, J. T.Sousa, R. A.Mano, J. F.Reis, R. L.2011-062011-06-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/12795eng0213-39111info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:43:32Zoai:repositorium.sdum.uminho.pt:1822/12795Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:41:02.199464Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration |
title |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration |
spellingShingle |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration Silva-Correia, Joana Gellan gum Intervertebral |
title_short |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration |
title_full |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration |
title_fullStr |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration |
title_full_unstemmed |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration |
title_sort |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration |
author |
Silva-Correia, Joana |
author_facet |
Silva-Correia, Joana Oliveira, Joaquim M. Caridade, S. G. Oliveira, J. T. Sousa, R. A. Mano, J. F. Reis, R. L. |
author_role |
author |
author2 |
Oliveira, Joaquim M. Caridade, S. G. Oliveira, J. T. Sousa, R. A. Mano, J. F. Reis, R. L. |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Silva-Correia, Joana Oliveira, Joaquim M. Caridade, S. G. Oliveira, J. T. Sousa, R. A. Mano, J. F. Reis, R. L. |
dc.subject.por.fl_str_mv |
Gellan gum Intervertebral |
topic |
Gellan gum Intervertebral |
description |
Intervertebral disc (IVD) degeneration is a challenging pathology that, due to the inefficiency of the current treatments, urgently demands for the development of new regenerative approaches[1]. The best viable implant material for nucleus pulposus (NP) regeneration has yet to be identified, but it is believed that biodegradable hydrogelbased materials are promising candidates[2]. In this work, we are proposing the use of ionic- and photocrosslinked methacrylated gellan gum (GG-MA) hydrogels as potential acellular and cellular injectable scaffolds for IVD regeneration. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-06 2011-06-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/12795 |
url |
http://hdl.handle.net/1822/12795 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0213-39111 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
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instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799132957845225472 |