The HBM4EU chromates study - Outcomes and impacts on EU policies and occupational health practices

Detalhes bibliográficos
Autor(a) principal: Santonen, Tiina
Data de Publicação: 2022
Outros Autores: Louro, Henriqueta, Bocca, Beatrice, Bousoumah, Radia, Duca, Radu Corneliu, Fucic, Aleksandra, Galea, Karen S., Godderis, Lode, Göen, Thomas, Iavicoli, Ivo, Janasik, Beata, Jones, Kate, Leese, Elizabeth, Leso, Veruscka, Ndaw, Sophie, Poels, Katrien, Porras, Simo P., Ruggieri, Flavia, Silva, Maria João, Van Nieuwenhuyse, An, Verdonck, Jelle, Wasowicz, Wojciech, Tavares, Ana, Sepai, Ovnair, Scheepers, Paul T.J., Viegas, Susana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/8544
Resumo: Within the EU human biomonitoring initiative (HBM4EU), a targeted, multi-national study on occupational exposure to hexavalent chromium (Cr(VI)) was performed. Cr(VI) is currently regulated in EU under REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) and under occupational safety and health (OSH) legislation. It has recently been subject to regulatory actions to improve its risk management in European workplaces. Analysis of the data obtained within the HBM4EU chromates study provides support both for the implementation of these regulatory actions and for national enforcement programs and may also contribute to the updating of occupational limit values (OELs) and biological limit values for Cr(VI). It also provides useful insights on the contribution of different risk management measures (RMMs) to further reduce the exposure to Cr(VI) and may support the evaluation of applications for authorisation under REACH. Findings on chrome platers’ additional per- and polyfluoroalkyl substances (PFAS) exposure highlight the need to also pay attention to this substance group in the metals sector. A survey performed to evaluate the policy relevance of the HBM4EU chromates study findings supports the usefulness of the study results. According to the responses received from the survey, the HBM4EU chromates study was able to demonstrate the added value of the human biomonitoring (HBM) approach in assessment and management of occupational exposure to Cr(VI). For future occupational studies, we emphasise the need for engagement of policy makers and regulators throughout the whole research process to ensure awareness, relevance and uptake of the results in future policies.
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spelling The HBM4EU chromates study - Outcomes and impacts on EU policies and occupational health practicesHexavalent ChromiumHuman BiomonitoringBiomonitoringCarcinogensOccupational Exposure Limit ValuesMutagens and Reprotoxic Substances DirectiveEnvironmental GenotoxicityEuropeGenotoxicidade AmbientalWithin the EU human biomonitoring initiative (HBM4EU), a targeted, multi-national study on occupational exposure to hexavalent chromium (Cr(VI)) was performed. Cr(VI) is currently regulated in EU under REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) and under occupational safety and health (OSH) legislation. It has recently been subject to regulatory actions to improve its risk management in European workplaces. Analysis of the data obtained within the HBM4EU chromates study provides support both for the implementation of these regulatory actions and for national enforcement programs and may also contribute to the updating of occupational limit values (OELs) and biological limit values for Cr(VI). It also provides useful insights on the contribution of different risk management measures (RMMs) to further reduce the exposure to Cr(VI) and may support the evaluation of applications for authorisation under REACH. Findings on chrome platers’ additional per- and polyfluoroalkyl substances (PFAS) exposure highlight the need to also pay attention to this substance group in the metals sector. A survey performed to evaluate the policy relevance of the HBM4EU chromates study findings supports the usefulness of the study results. According to the responses received from the survey, the HBM4EU chromates study was able to demonstrate the added value of the human biomonitoring (HBM) approach in assessment and management of occupational exposure to Cr(VI). For future occupational studies, we emphasise the need for engagement of policy makers and regulators throughout the whole research process to ensure awareness, relevance and uptake of the results in future policies.Highlights: Potential policy impact of the HBM4EU chromates study is presented and discussed; Surveyed policy makers confirmed policy relevance of biomonitoring results; Study considered to support national enforcement and further lowering of OELs; Added value of HBM in the management of occupational exposure to Cr(VI) was demonstrated; Close co-operation with regulators to support policy uptake is emphasised.Funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No 733032 and received co-funding from the author's organizations and/or Ministries.ElsevierRepositório Científico do Instituto Nacional de SaúdeSantonen, TiinaLouro, HenriquetaBocca, BeatriceBousoumah, RadiaDuca, Radu CorneliuFucic, AleksandraGalea, Karen S.Godderis, LodeGöen, ThomasIavicoli, IvoJanasik, BeataJones, KateLeese, ElizabethLeso, VerusckaNdaw, SophiePoels, KatrienPorras, Simo P.Ruggieri, FlaviaSilva, Maria JoãoVan Nieuwenhuyse, AnVerdonck, JelleWasowicz, WojciechTavares, AnaSepai, OvnairScheepers, Paul T.J.Viegas, Susana2023-03-03T13:54:06Z2022-12-172022-12-17T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/8544engInt J Hyg Environ Health. 2023 Mar;248:114099. doi: 10.1016/j.ijheh.2022.114099. Epub 2022 Dec 171438-463910.1016/j.ijheh.2022.114099info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:42:37Zoai:repositorio.insa.pt:10400.18/8544Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:43:11.063542Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The HBM4EU chromates study - Outcomes and impacts on EU policies and occupational health practices
title The HBM4EU chromates study - Outcomes and impacts on EU policies and occupational health practices
spellingShingle The HBM4EU chromates study - Outcomes and impacts on EU policies and occupational health practices
Santonen, Tiina
Hexavalent Chromium
Human Biomonitoring
Biomonitoring
Carcinogens
Occupational Exposure Limit Values
Mutagens and Reprotoxic Substances Directive
Environmental Genotoxicity
Europe
Genotoxicidade Ambiental
title_short The HBM4EU chromates study - Outcomes and impacts on EU policies and occupational health practices
title_full The HBM4EU chromates study - Outcomes and impacts on EU policies and occupational health practices
title_fullStr The HBM4EU chromates study - Outcomes and impacts on EU policies and occupational health practices
title_full_unstemmed The HBM4EU chromates study - Outcomes and impacts on EU policies and occupational health practices
title_sort The HBM4EU chromates study - Outcomes and impacts on EU policies and occupational health practices
author Santonen, Tiina
author_facet Santonen, Tiina
Louro, Henriqueta
Bocca, Beatrice
Bousoumah, Radia
Duca, Radu Corneliu
Fucic, Aleksandra
Galea, Karen S.
Godderis, Lode
Göen, Thomas
Iavicoli, Ivo
Janasik, Beata
Jones, Kate
Leese, Elizabeth
Leso, Veruscka
Ndaw, Sophie
Poels, Katrien
Porras, Simo P.
Ruggieri, Flavia
Silva, Maria João
Van Nieuwenhuyse, An
Verdonck, Jelle
Wasowicz, Wojciech
Tavares, Ana
Sepai, Ovnair
Scheepers, Paul T.J.
Viegas, Susana
author_role author
author2 Louro, Henriqueta
Bocca, Beatrice
Bousoumah, Radia
Duca, Radu Corneliu
Fucic, Aleksandra
Galea, Karen S.
Godderis, Lode
Göen, Thomas
Iavicoli, Ivo
Janasik, Beata
Jones, Kate
Leese, Elizabeth
Leso, Veruscka
Ndaw, Sophie
Poels, Katrien
Porras, Simo P.
Ruggieri, Flavia
Silva, Maria João
Van Nieuwenhuyse, An
Verdonck, Jelle
Wasowicz, Wojciech
Tavares, Ana
Sepai, Ovnair
Scheepers, Paul T.J.
Viegas, Susana
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Santonen, Tiina
Louro, Henriqueta
Bocca, Beatrice
Bousoumah, Radia
Duca, Radu Corneliu
Fucic, Aleksandra
Galea, Karen S.
Godderis, Lode
Göen, Thomas
Iavicoli, Ivo
Janasik, Beata
Jones, Kate
Leese, Elizabeth
Leso, Veruscka
Ndaw, Sophie
Poels, Katrien
Porras, Simo P.
Ruggieri, Flavia
Silva, Maria João
Van Nieuwenhuyse, An
Verdonck, Jelle
Wasowicz, Wojciech
Tavares, Ana
Sepai, Ovnair
Scheepers, Paul T.J.
Viegas, Susana
dc.subject.por.fl_str_mv Hexavalent Chromium
Human Biomonitoring
Biomonitoring
Carcinogens
Occupational Exposure Limit Values
Mutagens and Reprotoxic Substances Directive
Environmental Genotoxicity
Europe
Genotoxicidade Ambiental
topic Hexavalent Chromium
Human Biomonitoring
Biomonitoring
Carcinogens
Occupational Exposure Limit Values
Mutagens and Reprotoxic Substances Directive
Environmental Genotoxicity
Europe
Genotoxicidade Ambiental
description Within the EU human biomonitoring initiative (HBM4EU), a targeted, multi-national study on occupational exposure to hexavalent chromium (Cr(VI)) was performed. Cr(VI) is currently regulated in EU under REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) and under occupational safety and health (OSH) legislation. It has recently been subject to regulatory actions to improve its risk management in European workplaces. Analysis of the data obtained within the HBM4EU chromates study provides support both for the implementation of these regulatory actions and for national enforcement programs and may also contribute to the updating of occupational limit values (OELs) and biological limit values for Cr(VI). It also provides useful insights on the contribution of different risk management measures (RMMs) to further reduce the exposure to Cr(VI) and may support the evaluation of applications for authorisation under REACH. Findings on chrome platers’ additional per- and polyfluoroalkyl substances (PFAS) exposure highlight the need to also pay attention to this substance group in the metals sector. A survey performed to evaluate the policy relevance of the HBM4EU chromates study findings supports the usefulness of the study results. According to the responses received from the survey, the HBM4EU chromates study was able to demonstrate the added value of the human biomonitoring (HBM) approach in assessment and management of occupational exposure to Cr(VI). For future occupational studies, we emphasise the need for engagement of policy makers and regulators throughout the whole research process to ensure awareness, relevance and uptake of the results in future policies.
publishDate 2022
dc.date.none.fl_str_mv 2022-12-17
2022-12-17T00:00:00Z
2023-03-03T13:54:06Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/8544
url http://hdl.handle.net/10400.18/8544
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Int J Hyg Environ Health. 2023 Mar;248:114099. doi: 10.1016/j.ijheh.2022.114099. Epub 2022 Dec 17
1438-4639
10.1016/j.ijheh.2022.114099
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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