Competing with precision: incentives for developing predictive biomarker tests

Detalhes bibliográficos
Autor(a) principal: Brekke, Kurt R.
Data de Publicação: 2022
Outros Autores: Dalen, Dag Morten, Straume, Odd Rune
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/76660
Resumo: We study the incentives of drug producers to develop predictive biomarkers, taking into account strategic interaction between drug producers and health plans.For this purpose we develop a two-dimensional spatial frame work that allows us to capture the informational role of biomarkers and their effects on price competition and treatment choices. Although biomarkers increase the information available to prescribers, we identify an anticompetitive effect on the prices set by producers of therapeutically substitutable drugs. We also find that better information about each patient's most therapeutically appropriate drug does not necessarily lead to more efficient treatment outcomes.
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spelling Competing with precision: incentives for developing predictive biomarker testsPharmaceutical marketsPrecision medicineTherapeutic competitionPredictive biomarkersWe study the incentives of drug producers to develop predictive biomarkers, taking into account strategic interaction between drug producers and health plans.For this purpose we develop a two-dimensional spatial frame work that allows us to capture the informational role of biomarkers and their effects on price competition and treatment choices. Although biomarkers increase the information available to prescribers, we identify an anticompetitive effect on the prices set by producers of therapeutically substitutable drugs. We also find that better information about each patient's most therapeutically appropriate drug does not necessarily lead to more efficient treatment outcomes.Universidade do Minho. Núcleo de Investigação em Políticas Económicas (NIPE)Universidade do MinhoBrekke, Kurt R.Dalen, Dag MortenStraume, Odd Rune2022-032022-03-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/76660enghttps://nipe.eeg.uminho.pt/publicacoes-nipe/#documentos-de-trabalhoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:39:35Zoai:repositorium.sdum.uminho.pt:1822/76660Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:36:12.794169Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Competing with precision: incentives for developing predictive biomarker tests
title Competing with precision: incentives for developing predictive biomarker tests
spellingShingle Competing with precision: incentives for developing predictive biomarker tests
Brekke, Kurt R.
Pharmaceutical markets
Precision medicine
Therapeutic competition
Predictive biomarkers
title_short Competing with precision: incentives for developing predictive biomarker tests
title_full Competing with precision: incentives for developing predictive biomarker tests
title_fullStr Competing with precision: incentives for developing predictive biomarker tests
title_full_unstemmed Competing with precision: incentives for developing predictive biomarker tests
title_sort Competing with precision: incentives for developing predictive biomarker tests
author Brekke, Kurt R.
author_facet Brekke, Kurt R.
Dalen, Dag Morten
Straume, Odd Rune
author_role author
author2 Dalen, Dag Morten
Straume, Odd Rune
author2_role author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Brekke, Kurt R.
Dalen, Dag Morten
Straume, Odd Rune
dc.subject.por.fl_str_mv Pharmaceutical markets
Precision medicine
Therapeutic competition
Predictive biomarkers
topic Pharmaceutical markets
Precision medicine
Therapeutic competition
Predictive biomarkers
description We study the incentives of drug producers to develop predictive biomarkers, taking into account strategic interaction between drug producers and health plans.For this purpose we develop a two-dimensional spatial frame work that allows us to capture the informational role of biomarkers and their effects on price competition and treatment choices. Although biomarkers increase the information available to prescribers, we identify an anticompetitive effect on the prices set by producers of therapeutically substitutable drugs. We also find that better information about each patient's most therapeutically appropriate drug does not necessarily lead to more efficient treatment outcomes.
publishDate 2022
dc.date.none.fl_str_mv 2022-03
2022-03-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/76660
url http://hdl.handle.net/1822/76660
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://nipe.eeg.uminho.pt/publicacoes-nipe/#documentos-de-trabalho
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade do Minho. Núcleo de Investigação em Políticas Económicas (NIPE)
publisher.none.fl_str_mv Universidade do Minho. Núcleo de Investigação em Políticas Económicas (NIPE)
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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