Competing with precision: incentives for developing predictive biomarker tests
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/76660 |
Resumo: | We study the incentives of drug producers to develop predictive biomarkers, taking into account strategic interaction between drug producers and health plans.For this purpose we develop a two-dimensional spatial frame work that allows us to capture the informational role of biomarkers and their effects on price competition and treatment choices. Although biomarkers increase the information available to prescribers, we identify an anticompetitive effect on the prices set by producers of therapeutically substitutable drugs. We also find that better information about each patient's most therapeutically appropriate drug does not necessarily lead to more efficient treatment outcomes. |
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Competing with precision: incentives for developing predictive biomarker testsPharmaceutical marketsPrecision medicineTherapeutic competitionPredictive biomarkersWe study the incentives of drug producers to develop predictive biomarkers, taking into account strategic interaction between drug producers and health plans.For this purpose we develop a two-dimensional spatial frame work that allows us to capture the informational role of biomarkers and their effects on price competition and treatment choices. Although biomarkers increase the information available to prescribers, we identify an anticompetitive effect on the prices set by producers of therapeutically substitutable drugs. We also find that better information about each patient's most therapeutically appropriate drug does not necessarily lead to more efficient treatment outcomes.Universidade do Minho. Núcleo de Investigação em Políticas Económicas (NIPE)Universidade do MinhoBrekke, Kurt R.Dalen, Dag MortenStraume, Odd Rune2022-032022-03-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/76660enghttps://nipe.eeg.uminho.pt/publicacoes-nipe/#documentos-de-trabalhoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:39:35Zoai:repositorium.sdum.uminho.pt:1822/76660Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:36:12.794169Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Competing with precision: incentives for developing predictive biomarker tests |
title |
Competing with precision: incentives for developing predictive biomarker tests |
spellingShingle |
Competing with precision: incentives for developing predictive biomarker tests Brekke, Kurt R. Pharmaceutical markets Precision medicine Therapeutic competition Predictive biomarkers |
title_short |
Competing with precision: incentives for developing predictive biomarker tests |
title_full |
Competing with precision: incentives for developing predictive biomarker tests |
title_fullStr |
Competing with precision: incentives for developing predictive biomarker tests |
title_full_unstemmed |
Competing with precision: incentives for developing predictive biomarker tests |
title_sort |
Competing with precision: incentives for developing predictive biomarker tests |
author |
Brekke, Kurt R. |
author_facet |
Brekke, Kurt R. Dalen, Dag Morten Straume, Odd Rune |
author_role |
author |
author2 |
Dalen, Dag Morten Straume, Odd Rune |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Brekke, Kurt R. Dalen, Dag Morten Straume, Odd Rune |
dc.subject.por.fl_str_mv |
Pharmaceutical markets Precision medicine Therapeutic competition Predictive biomarkers |
topic |
Pharmaceutical markets Precision medicine Therapeutic competition Predictive biomarkers |
description |
We study the incentives of drug producers to develop predictive biomarkers, taking into account strategic interaction between drug producers and health plans.For this purpose we develop a two-dimensional spatial frame work that allows us to capture the informational role of biomarkers and their effects on price competition and treatment choices. Although biomarkers increase the information available to prescribers, we identify an anticompetitive effect on the prices set by producers of therapeutically substitutable drugs. We also find that better information about each patient's most therapeutically appropriate drug does not necessarily lead to more efficient treatment outcomes. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-03 2022-03-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/76660 |
url |
http://hdl.handle.net/1822/76660 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://nipe.eeg.uminho.pt/publicacoes-nipe/#documentos-de-trabalho |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade do Minho. Núcleo de Investigação em Políticas Económicas (NIPE) |
publisher.none.fl_str_mv |
Universidade do Minho. Núcleo de Investigação em Políticas Económicas (NIPE) |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799132890745798656 |