Quality of life in patients with mild cognitive impairment
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.12/2451 |
Resumo: | Background: Quality of life (QoL) is affected in patients with dementia, but it is not clear whether it is already disturbed in more initial phases of cognitive decline, like Mild Cognitive Impairment (MCI). Aim: Compare the QoL in MCI patients with controls without cognitive impairment, and ascertain whether there are differences in the reports of QoL made by the subjects and by their informants. Methods: Two hundred participants were enrolled, divided into MCI patients (n¼50), MCI informants (n¼50), recruited from a memory clinic and a dementia outpatient clinic, and controls (n¼50) and controls informants (n¼50), recruited in a family practice clinic. QoL was assessed with the QoL in Alzheimer disease (QOL-AD) scale. Results: The total scores of the QOL-AD questionnaire were 32.1 6.9 for MCI patients self-report, 27.2 6.7 for MCI patients in the opinion of their informants, 35.3 4.9 for controls self-report and 35.6 4.9 for controls in the opinion of their informants. MCI patients had lower QOL-AD scores than controls. The QoL reported by patients with MCI was more favorable than the opinion of their informants. Conclusion: The QoL is affected at early stages of cognitive decline. The QoL reported by patients with MCI is better than the opinion of their informants, similarly to what is known in Alzheimer’s disease patients. QoL appears to be an important domain to be evaluated in aging studies. |
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Quality of life in patients with mild cognitive impairmentQOL-ADMCIAlzheimer’s diseaseCaregiver-reportSelf-reportBackground: Quality of life (QoL) is affected in patients with dementia, but it is not clear whether it is already disturbed in more initial phases of cognitive decline, like Mild Cognitive Impairment (MCI). Aim: Compare the QoL in MCI patients with controls without cognitive impairment, and ascertain whether there are differences in the reports of QoL made by the subjects and by their informants. Methods: Two hundred participants were enrolled, divided into MCI patients (n¼50), MCI informants (n¼50), recruited from a memory clinic and a dementia outpatient clinic, and controls (n¼50) and controls informants (n¼50), recruited in a family practice clinic. QoL was assessed with the QoL in Alzheimer disease (QOL-AD) scale. Results: The total scores of the QOL-AD questionnaire were 32.1 6.9 for MCI patients self-report, 27.2 6.7 for MCI patients in the opinion of their informants, 35.3 4.9 for controls self-report and 35.6 4.9 for controls in the opinion of their informants. MCI patients had lower QOL-AD scores than controls. The QoL reported by patients with MCI was more favorable than the opinion of their informants. Conclusion: The QoL is affected at early stages of cognitive decline. The QoL reported by patients with MCI is better than the opinion of their informants, similarly to what is known in Alzheimer’s disease patients. QoL appears to be an important domain to be evaluated in aging studies.RoutledgeRepositório do ISPABárrios, HelenaNarciso, SofiaGuerreiro, ManuelaMaroco, JoãoLogsdon, RebeccaMendonça, Alexandre de2013-10-28T19:47:10Z2013-01-01T00:00:00Z2013-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.12/2451engAging & Mental Health, 17, 287-2921360-7863info:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-05T16:38:22Zoai:repositorio.ispa.pt:10400.12/2451Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:20:25.670457Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Quality of life in patients with mild cognitive impairment |
title |
Quality of life in patients with mild cognitive impairment |
spellingShingle |
Quality of life in patients with mild cognitive impairment Bárrios, Helena QOL-AD MCI Alzheimer’s disease Caregiver-report Self-report |
title_short |
Quality of life in patients with mild cognitive impairment |
title_full |
Quality of life in patients with mild cognitive impairment |
title_fullStr |
Quality of life in patients with mild cognitive impairment |
title_full_unstemmed |
Quality of life in patients with mild cognitive impairment |
title_sort |
Quality of life in patients with mild cognitive impairment |
author |
Bárrios, Helena |
author_facet |
Bárrios, Helena Narciso, Sofia Guerreiro, Manuela Maroco, João Logsdon, Rebecca Mendonça, Alexandre de |
author_role |
author |
author2 |
Narciso, Sofia Guerreiro, Manuela Maroco, João Logsdon, Rebecca Mendonça, Alexandre de |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Repositório do ISPA |
dc.contributor.author.fl_str_mv |
Bárrios, Helena Narciso, Sofia Guerreiro, Manuela Maroco, João Logsdon, Rebecca Mendonça, Alexandre de |
dc.subject.por.fl_str_mv |
QOL-AD MCI Alzheimer’s disease Caregiver-report Self-report |
topic |
QOL-AD MCI Alzheimer’s disease Caregiver-report Self-report |
description |
Background: Quality of life (QoL) is affected in patients with dementia, but it is not clear whether it is already disturbed in more initial phases of cognitive decline, like Mild Cognitive Impairment (MCI). Aim: Compare the QoL in MCI patients with controls without cognitive impairment, and ascertain whether there are differences in the reports of QoL made by the subjects and by their informants. Methods: Two hundred participants were enrolled, divided into MCI patients (n¼50), MCI informants (n¼50), recruited from a memory clinic and a dementia outpatient clinic, and controls (n¼50) and controls informants (n¼50), recruited in a family practice clinic. QoL was assessed with the QoL in Alzheimer disease (QOL-AD) scale. Results: The total scores of the QOL-AD questionnaire were 32.1 6.9 for MCI patients self-report, 27.2 6.7 for MCI patients in the opinion of their informants, 35.3 4.9 for controls self-report and 35.6 4.9 for controls in the opinion of their informants. MCI patients had lower QOL-AD scores than controls. The QoL reported by patients with MCI was more favorable than the opinion of their informants. Conclusion: The QoL is affected at early stages of cognitive decline. The QoL reported by patients with MCI is better than the opinion of their informants, similarly to what is known in Alzheimer’s disease patients. QoL appears to be an important domain to be evaluated in aging studies. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-10-28T19:47:10Z 2013-01-01T00:00:00Z 2013-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.12/2451 |
url |
http://hdl.handle.net/10400.12/2451 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Aging & Mental Health, 17, 287-292 1360-7863 |
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info:eu-repo/semantics/embargoedAccess |
eu_rights_str_mv |
embargoedAccess |
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application/pdf |
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Routledge |
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Routledge |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799130065453187072 |