Development of liposomes with affinity to ischemic myocardium

Detalhes bibliográficos
Autor(a) principal: Antunes, A.
Data de Publicação: 2004
Outros Autores: Botelho, M. F., Gomes, C., Lima, J. J. P. de, Silva, M. L., Moreira, J. N., Simões, S., Gonçalves, L., Providência, L. A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/4784
https://doi.org/10.1016/j.nuclcard.2004.06.066
Resumo: Background: A major impediment to drug diagnosis and therapy of myocardial infarction is the limited access that drugs have to ischemic myocardium, dependent on regional myocardial blood flow. Investigators report that some liposomes concentrate in the experimental myocardial infarction, suggesting that they may be used to transport drugs to a region of ischemia. One of the most promising approaches for increasing liposome circulation time is coating them with polyethyleneglycol (PEG).
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spelling Development of liposomes with affinity to ischemic myocardiumBackground: A major impediment to drug diagnosis and therapy of myocardial infarction is the limited access that drugs have to ischemic myocardium, dependent on regional myocardial blood flow. Investigators report that some liposomes concentrate in the experimental myocardial infarction, suggesting that they may be used to transport drugs to a region of ischemia. One of the most promising approaches for increasing liposome circulation time is coating them with polyethyleneglycol (PEG).http://www.sciencedirect.com/science/article/B6WKC-4D0XVDT-3B/1/e8e1e8ec0cf1dcf1546291ba169facff2004info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleaplication/PDFhttp://hdl.handle.net/10316/4784http://hdl.handle.net/10316/4784https://doi.org/10.1016/j.nuclcard.2004.06.066engJournal of Nuclear Cardiology. 11:4 (2004) S21-S21Antunes, A.Botelho, M. F.Gomes, C.Lima, J. J. P. deSilva, M. L.Moreira, J. N.Simões, S.Gonçalves, L.Providência, L. A.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2020-11-06T16:49:24Zoai:estudogeral.uc.pt:10316/4784Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:43:34.899676Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Development of liposomes with affinity to ischemic myocardium
title Development of liposomes with affinity to ischemic myocardium
spellingShingle Development of liposomes with affinity to ischemic myocardium
Antunes, A.
title_short Development of liposomes with affinity to ischemic myocardium
title_full Development of liposomes with affinity to ischemic myocardium
title_fullStr Development of liposomes with affinity to ischemic myocardium
title_full_unstemmed Development of liposomes with affinity to ischemic myocardium
title_sort Development of liposomes with affinity to ischemic myocardium
author Antunes, A.
author_facet Antunes, A.
Botelho, M. F.
Gomes, C.
Lima, J. J. P. de
Silva, M. L.
Moreira, J. N.
Simões, S.
Gonçalves, L.
Providência, L. A.
author_role author
author2 Botelho, M. F.
Gomes, C.
Lima, J. J. P. de
Silva, M. L.
Moreira, J. N.
Simões, S.
Gonçalves, L.
Providência, L. A.
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Antunes, A.
Botelho, M. F.
Gomes, C.
Lima, J. J. P. de
Silva, M. L.
Moreira, J. N.
Simões, S.
Gonçalves, L.
Providência, L. A.
description Background: A major impediment to drug diagnosis and therapy of myocardial infarction is the limited access that drugs have to ischemic myocardium, dependent on regional myocardial blood flow. Investigators report that some liposomes concentrate in the experimental myocardial infarction, suggesting that they may be used to transport drugs to a region of ischemia. One of the most promising approaches for increasing liposome circulation time is coating them with polyethyleneglycol (PEG).
publishDate 2004
dc.date.none.fl_str_mv 2004
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/4784
http://hdl.handle.net/10316/4784
https://doi.org/10.1016/j.nuclcard.2004.06.066
url http://hdl.handle.net/10316/4784
https://doi.org/10.1016/j.nuclcard.2004.06.066
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Nuclear Cardiology. 11:4 (2004) S21-S21
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv aplication/PDF
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