Development of liposomes with affinity to ischemic myocardium
Autor(a) principal: | |
---|---|
Data de Publicação: | 2004 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/4784 https://doi.org/10.1016/j.nuclcard.2004.06.066 |
Resumo: | Background: A major impediment to drug diagnosis and therapy of myocardial infarction is the limited access that drugs have to ischemic myocardium, dependent on regional myocardial blood flow. Investigators report that some liposomes concentrate in the experimental myocardial infarction, suggesting that they may be used to transport drugs to a region of ischemia. One of the most promising approaches for increasing liposome circulation time is coating them with polyethyleneglycol (PEG). |
id |
RCAP_4cf0583652ea4b4af04d86ebe6369ad6 |
---|---|
oai_identifier_str |
oai:estudogeral.uc.pt:10316/4784 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Development of liposomes with affinity to ischemic myocardiumBackground: A major impediment to drug diagnosis and therapy of myocardial infarction is the limited access that drugs have to ischemic myocardium, dependent on regional myocardial blood flow. Investigators report that some liposomes concentrate in the experimental myocardial infarction, suggesting that they may be used to transport drugs to a region of ischemia. One of the most promising approaches for increasing liposome circulation time is coating them with polyethyleneglycol (PEG).http://www.sciencedirect.com/science/article/B6WKC-4D0XVDT-3B/1/e8e1e8ec0cf1dcf1546291ba169facff2004info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleaplication/PDFhttp://hdl.handle.net/10316/4784http://hdl.handle.net/10316/4784https://doi.org/10.1016/j.nuclcard.2004.06.066engJournal of Nuclear Cardiology. 11:4 (2004) S21-S21Antunes, A.Botelho, M. F.Gomes, C.Lima, J. J. P. deSilva, M. L.Moreira, J. N.Simões, S.Gonçalves, L.Providência, L. A.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2020-11-06T16:49:24Zoai:estudogeral.uc.pt:10316/4784Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:43:34.899676Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Development of liposomes with affinity to ischemic myocardium |
title |
Development of liposomes with affinity to ischemic myocardium |
spellingShingle |
Development of liposomes with affinity to ischemic myocardium Antunes, A. |
title_short |
Development of liposomes with affinity to ischemic myocardium |
title_full |
Development of liposomes with affinity to ischemic myocardium |
title_fullStr |
Development of liposomes with affinity to ischemic myocardium |
title_full_unstemmed |
Development of liposomes with affinity to ischemic myocardium |
title_sort |
Development of liposomes with affinity to ischemic myocardium |
author |
Antunes, A. |
author_facet |
Antunes, A. Botelho, M. F. Gomes, C. Lima, J. J. P. de Silva, M. L. Moreira, J. N. Simões, S. Gonçalves, L. Providência, L. A. |
author_role |
author |
author2 |
Botelho, M. F. Gomes, C. Lima, J. J. P. de Silva, M. L. Moreira, J. N. Simões, S. Gonçalves, L. Providência, L. A. |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Antunes, A. Botelho, M. F. Gomes, C. Lima, J. J. P. de Silva, M. L. Moreira, J. N. Simões, S. Gonçalves, L. Providência, L. A. |
description |
Background: A major impediment to drug diagnosis and therapy of myocardial infarction is the limited access that drugs have to ischemic myocardium, dependent on regional myocardial blood flow. Investigators report that some liposomes concentrate in the experimental myocardial infarction, suggesting that they may be used to transport drugs to a region of ischemia. One of the most promising approaches for increasing liposome circulation time is coating them with polyethyleneglycol (PEG). |
publishDate |
2004 |
dc.date.none.fl_str_mv |
2004 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/4784 http://hdl.handle.net/10316/4784 https://doi.org/10.1016/j.nuclcard.2004.06.066 |
url |
http://hdl.handle.net/10316/4784 https://doi.org/10.1016/j.nuclcard.2004.06.066 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Nuclear Cardiology. 11:4 (2004) S21-S21 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
aplication/PDF |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799133707835015168 |