Influence of P53 on the radiotherapy response of hepatocellular carcinoma

Detalhes bibliográficos
Autor(a) principal: Gomes, AR
Data de Publicação: 2015
Outros Autores: Abrantes, AM, Brito, AF, Laranjo, M, Casalta-Lopes, JE, Gonçalves, AC, Sarmento-Ribeiro, AB, Botelho, MF, Tralhão, JG
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.4/1898
Resumo: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and it has a poor prognosis and few therapeutic options. Radiotherapy is one of the most effective forms of cancer treatment, and P53 protein is one of the key molecules determining how a cell responds to radiotherapy. The aim of this study was to determine the therapeutic efficacy of iodine-131 in three human HCC cell lines.
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spelling Influence of P53 on the radiotherapy response of hepatocellular carcinomaCarcinoma HepatocelularProteína Supressora de Tumor p53Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and it has a poor prognosis and few therapeutic options. Radiotherapy is one of the most effective forms of cancer treatment, and P53 protein is one of the key molecules determining how a cell responds to radiotherapy. The aim of this study was to determine the therapeutic efficacy of iodine-131 in three human HCC cell lines.RIHUCGomes, ARAbrantes, AMBrito, AFLaranjo, MCasalta-Lopes, JEGonçalves, ACSarmento-Ribeiro, ABBotelho, MFTralhão, JG2016-05-11T15:58:18Z2015-092015-09-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.4/1898engClin Mol Hepatol. 2015 Sep;21(3):257-67.10.3350/cmh.2015.21.3.257info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-11T14:23:11Zoai:rihuc.huc.min-saude.pt:10400.4/1898Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:04:20.904455Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Influence of P53 on the radiotherapy response of hepatocellular carcinoma
title Influence of P53 on the radiotherapy response of hepatocellular carcinoma
spellingShingle Influence of P53 on the radiotherapy response of hepatocellular carcinoma
Gomes, AR
Carcinoma Hepatocelular
Proteína Supressora de Tumor p53
title_short Influence of P53 on the radiotherapy response of hepatocellular carcinoma
title_full Influence of P53 on the radiotherapy response of hepatocellular carcinoma
title_fullStr Influence of P53 on the radiotherapy response of hepatocellular carcinoma
title_full_unstemmed Influence of P53 on the radiotherapy response of hepatocellular carcinoma
title_sort Influence of P53 on the radiotherapy response of hepatocellular carcinoma
author Gomes, AR
author_facet Gomes, AR
Abrantes, AM
Brito, AF
Laranjo, M
Casalta-Lopes, JE
Gonçalves, AC
Sarmento-Ribeiro, AB
Botelho, MF
Tralhão, JG
author_role author
author2 Abrantes, AM
Brito, AF
Laranjo, M
Casalta-Lopes, JE
Gonçalves, AC
Sarmento-Ribeiro, AB
Botelho, MF
Tralhão, JG
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv RIHUC
dc.contributor.author.fl_str_mv Gomes, AR
Abrantes, AM
Brito, AF
Laranjo, M
Casalta-Lopes, JE
Gonçalves, AC
Sarmento-Ribeiro, AB
Botelho, MF
Tralhão, JG
dc.subject.por.fl_str_mv Carcinoma Hepatocelular
Proteína Supressora de Tumor p53
topic Carcinoma Hepatocelular
Proteína Supressora de Tumor p53
description Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and it has a poor prognosis and few therapeutic options. Radiotherapy is one of the most effective forms of cancer treatment, and P53 protein is one of the key molecules determining how a cell responds to radiotherapy. The aim of this study was to determine the therapeutic efficacy of iodine-131 in three human HCC cell lines.
publishDate 2015
dc.date.none.fl_str_mv 2015-09
2015-09-01T00:00:00Z
2016-05-11T15:58:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.4/1898
url http://hdl.handle.net/10400.4/1898
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Clin Mol Hepatol. 2015 Sep;21(3):257-67.
10.3350/cmh.2015.21.3.257
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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