Cosmetic potential of marine fish skin collagen

Detalhes bibliográficos
Autor(a) principal: Alves, Ana L.
Data de Publicação: 2017
Outros Autores: Marques, Ana L. P, Martins, Eva, Silva, Tiago José Quinteiros Lopes Henriques, Reis, R. L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/51397
Resumo: Many cosmetic formulations have collagen as a major component because of its significant benefits as a natural humectant and moisturizer. This industry is constantly looking for innovative, sustainable, and truly efficacious products, so marine collagen based formulations are arising as promising alternatives. A solid description and characterization of this protein is fundamental to guarantee the highest quality of each batch. In the present study, we present an extensive characterization of marine-derived collagen extracted from salmon and codfish skins, targeting its inclusion as component in cosmetic formulations. Chemical and physical characterizations were performed using several techniques such as sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), Fourier Transformation Infrared (FTIR) spectroscopy rheology, circular dichroism, X-ray diffraction, humidity uptake, and a biological assessment of the extracts regarding their irritant potential. The results showed an isolation of type I collagen with high purity but with some structural and chemical differences between sources. Collagen demonstrated a good capacity to retain water, thus being suitable for dermal applications as a moisturizer. A topical exposure of collagen in a human reconstructed dermis, as well as the analysis of molecular markers for irritation and inflammation, exhibited no irritant potential. Thus, the isolation of collagen from fish skins for inclusion in dermocosmetic applications may constitute a sustainable and low-cost platform for the biotechnological valorization of fish by-products.
id RCAP_5429dd3bd1869dd6e89178b9d16c8ce0
oai_identifier_str oai:repositorium.sdum.uminho.pt:1822/51397
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Cosmetic potential of marine fish skin collagenCosmetic applicationFish collagenMarine biomaterialsMarine collagenValorization of fish by-products moisturizerMany cosmetic formulations have collagen as a major component because of its significant benefits as a natural humectant and moisturizer. This industry is constantly looking for innovative, sustainable, and truly efficacious products, so marine collagen based formulations are arising as promising alternatives. A solid description and characterization of this protein is fundamental to guarantee the highest quality of each batch. In the present study, we present an extensive characterization of marine-derived collagen extracted from salmon and codfish skins, targeting its inclusion as component in cosmetic formulations. Chemical and physical characterizations were performed using several techniques such as sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), Fourier Transformation Infrared (FTIR) spectroscopy rheology, circular dichroism, X-ray diffraction, humidity uptake, and a biological assessment of the extracts regarding their irritant potential. The results showed an isolation of type I collagen with high purity but with some structural and chemical differences between sources. Collagen demonstrated a good capacity to retain water, thus being suitable for dermal applications as a moisturizer. A topical exposure of collagen in a human reconstructed dermis, as well as the analysis of molecular markers for irritation and inflammation, exhibited no irritant potential. Thus, the isolation of collagen from fish skins for inclusion in dermocosmetic applications may constitute a sustainable and low-cost platform for the biotechnological valorization of fish by-products.The authors would like to acknowledge to European Union for the financial support under the scope of European Regional Development Fund (ERDF) through the projects 0687_NOVOMAR_1_P (POCTEP (Programa Operacional de Cooperação Transfronteiriça España-Portugal) 2007/2013) and 0302_CVMAR_I_1_P (POCTEP 2014/2020) and the Structured Project NORTE-01-0145-FEDER-000021 (Norte2020) and under the scope of the European Union Seventh Framework Programme (FP7/2007-2013) through grant agreement ERC-2012-ADG 20120216-321266 (ERC Advanced Grant ComplexiTE). The Portuguese Foundation for Science and Technology is also acknowledged for the grant of A.L.A (Ana Luísa Alves.) under Doctoral Programme Do* Mar (PD/BD/127995/2016).info:eu-repo/semantics/publishedVersionMDPIUniversidade do MinhoAlves, Ana L.Marques, Ana L. PMartins, EvaSilva, Tiago José Quinteiros Lopes HenriquesReis, R. L.2017-10-122017-10-12T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/51397engAlves A. L., Marques A. L., Martins E., Silva T. H., Reis R. L. Cosmetic Potential of Marine Fish Skin Collagen, Cosmetics, Vol. 4, Issue 4, doi:10.3390/cosmetics4040039, 20172079-928410.3390/cosmetics4040039http://www.mdpi.com/2079-9284/4/4/39info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:22:12Zoai:repositorium.sdum.uminho.pt:1822/51397Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:15:40.218635Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Cosmetic potential of marine fish skin collagen
title Cosmetic potential of marine fish skin collagen
spellingShingle Cosmetic potential of marine fish skin collagen
Alves, Ana L.
Cosmetic application
Fish collagen
Marine biomaterials
Marine collagen
Valorization of fish by-products moisturizer
title_short Cosmetic potential of marine fish skin collagen
title_full Cosmetic potential of marine fish skin collagen
title_fullStr Cosmetic potential of marine fish skin collagen
title_full_unstemmed Cosmetic potential of marine fish skin collagen
title_sort Cosmetic potential of marine fish skin collagen
author Alves, Ana L.
author_facet Alves, Ana L.
Marques, Ana L. P
Martins, Eva
Silva, Tiago José Quinteiros Lopes Henriques
Reis, R. L.
author_role author
author2 Marques, Ana L. P
Martins, Eva
Silva, Tiago José Quinteiros Lopes Henriques
Reis, R. L.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Alves, Ana L.
Marques, Ana L. P
Martins, Eva
Silva, Tiago José Quinteiros Lopes Henriques
Reis, R. L.
dc.subject.por.fl_str_mv Cosmetic application
Fish collagen
Marine biomaterials
Marine collagen
Valorization of fish by-products moisturizer
topic Cosmetic application
Fish collagen
Marine biomaterials
Marine collagen
Valorization of fish by-products moisturizer
description Many cosmetic formulations have collagen as a major component because of its significant benefits as a natural humectant and moisturizer. This industry is constantly looking for innovative, sustainable, and truly efficacious products, so marine collagen based formulations are arising as promising alternatives. A solid description and characterization of this protein is fundamental to guarantee the highest quality of each batch. In the present study, we present an extensive characterization of marine-derived collagen extracted from salmon and codfish skins, targeting its inclusion as component in cosmetic formulations. Chemical and physical characterizations were performed using several techniques such as sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), Fourier Transformation Infrared (FTIR) spectroscopy rheology, circular dichroism, X-ray diffraction, humidity uptake, and a biological assessment of the extracts regarding their irritant potential. The results showed an isolation of type I collagen with high purity but with some structural and chemical differences between sources. Collagen demonstrated a good capacity to retain water, thus being suitable for dermal applications as a moisturizer. A topical exposure of collagen in a human reconstructed dermis, as well as the analysis of molecular markers for irritation and inflammation, exhibited no irritant potential. Thus, the isolation of collagen from fish skins for inclusion in dermocosmetic applications may constitute a sustainable and low-cost platform for the biotechnological valorization of fish by-products.
publishDate 2017
dc.date.none.fl_str_mv 2017-10-12
2017-10-12T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/51397
url http://hdl.handle.net/1822/51397
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Alves A. L., Marques A. L., Martins E., Silva T. H., Reis R. L. Cosmetic Potential of Marine Fish Skin Collagen, Cosmetics, Vol. 4, Issue 4, doi:10.3390/cosmetics4040039, 2017
2079-9284
10.3390/cosmetics4040039
http://www.mdpi.com/2079-9284/4/4/39
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799132602590822400