Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L.
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/9172 |
Resumo: | The bioactive properties (antioxidant and antitumour activities, and hepatotoxicity) of the infusion and methanolic extracts of Chenopodium ambrosioides L., a plant commonly used in Portuguese folk medicine, were compared. The chemical composition in hydrophilic (sugars, organic acids and phenolic compounds) and lipophilic (fatty acids and tocopherols) fractions were determined. In general, the infusion revealed higher antioxidant activity, while the methanolic extract was the only one showing antitumour effects against colon, cervical and hepatocellular carcinoma cell lines. No toxicity in non-tumour cells was observed either for the infusion or the extract. The studied plant proved to be a good source of natural antioxidants and other bioactive compounds, which may have industrial use. As far as we know, this is the first detailed chemical characterization and bioactivity evaluation of C. ambrosioides methanolic extract and infusion. |
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Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L.Chenopodium ambrosioides L.Antioxidant activityAntitumour activityChemical compoundsThe bioactive properties (antioxidant and antitumour activities, and hepatotoxicity) of the infusion and methanolic extracts of Chenopodium ambrosioides L., a plant commonly used in Portuguese folk medicine, were compared. The chemical composition in hydrophilic (sugars, organic acids and phenolic compounds) and lipophilic (fatty acids and tocopherols) fractions were determined. In general, the infusion revealed higher antioxidant activity, while the methanolic extract was the only one showing antitumour effects against colon, cervical and hepatocellular carcinoma cell lines. No toxicity in non-tumour cells was observed either for the infusion or the extract. The studied plant proved to be a good source of natural antioxidants and other bioactive compounds, which may have industrial use. As far as we know, this is the first detailed chemical characterization and bioactivity evaluation of C. ambrosioides methanolic extract and infusion.Fundação para a Ciência e a Tecnologia (FCT, Portugal) for financial support to CIMO (strategic project PEst-OE/AGR/UI0690/2011). R.C. Calhelha and L. Barros also thank to FCT, POPH-QREN and FSE for their grants (SFRH/BPD/ BPD/68344/2010 and SFRH/BPD/4609/2008, respectively). The GIP-USAL is financially supported by the Spanish Government through the Consolider-Ingenio 2010 Programme (FUN-C-FOOD, CSD2007-00063). M. Dueñas thanks to the Programa Ramón y Cajal for a contract.Biblioteca Digital do IPBBarros, LillianPereira, ElianaCalhelha, Ricardo C.Dueñas, MontserratCarvalho, Ana MariaSantos-Buelga, CelestinoFerreira, Isabel C.F.R.2014-01-27T11:59:27Z20132013-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/10198/9172engBarros, Lillian; Pereira, Eliana; Calhelha, Ricardo C.; Dueñas, Montserrat; Carvalho, Ana Maria; Santos-Buelga, Celestino; Ferrreira, Isabel C.F.R. (2013). Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L. Journal of Functional Foods. ISSN 1756-4646. 5:4, p. 1732–17401756-4646info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:22:09Zoai:bibliotecadigital.ipb.pt:10198/9172Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:00:27.006028Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L. |
title |
Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L. |
spellingShingle |
Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L. Barros, Lillian Chenopodium ambrosioides L. Antioxidant activity Antitumour activity Chemical compounds |
title_short |
Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L. |
title_full |
Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L. |
title_fullStr |
Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L. |
title_full_unstemmed |
Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L. |
title_sort |
Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L. |
author |
Barros, Lillian |
author_facet |
Barros, Lillian Pereira, Eliana Calhelha, Ricardo C. Dueñas, Montserrat Carvalho, Ana Maria Santos-Buelga, Celestino Ferreira, Isabel C.F.R. |
author_role |
author |
author2 |
Pereira, Eliana Calhelha, Ricardo C. Dueñas, Montserrat Carvalho, Ana Maria Santos-Buelga, Celestino Ferreira, Isabel C.F.R. |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Barros, Lillian Pereira, Eliana Calhelha, Ricardo C. Dueñas, Montserrat Carvalho, Ana Maria Santos-Buelga, Celestino Ferreira, Isabel C.F.R. |
dc.subject.por.fl_str_mv |
Chenopodium ambrosioides L. Antioxidant activity Antitumour activity Chemical compounds |
topic |
Chenopodium ambrosioides L. Antioxidant activity Antitumour activity Chemical compounds |
description |
The bioactive properties (antioxidant and antitumour activities, and hepatotoxicity) of the infusion and methanolic extracts of Chenopodium ambrosioides L., a plant commonly used in Portuguese folk medicine, were compared. The chemical composition in hydrophilic (sugars, organic acids and phenolic compounds) and lipophilic (fatty acids and tocopherols) fractions were determined. In general, the infusion revealed higher antioxidant activity, while the methanolic extract was the only one showing antitumour effects against colon, cervical and hepatocellular carcinoma cell lines. No toxicity in non-tumour cells was observed either for the infusion or the extract. The studied plant proved to be a good source of natural antioxidants and other bioactive compounds, which may have industrial use. As far as we know, this is the first detailed chemical characterization and bioactivity evaluation of C. ambrosioides methanolic extract and infusion. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013 2013-01-01T00:00:00Z 2014-01-27T11:59:27Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/9172 |
url |
http://hdl.handle.net/10198/9172 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Barros, Lillian; Pereira, Eliana; Calhelha, Ricardo C.; Dueñas, Montserrat; Carvalho, Ana Maria; Santos-Buelga, Celestino; Ferrreira, Isabel C.F.R. (2013). Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L. Journal of Functional Foods. ISSN 1756-4646. 5:4, p. 1732–1740 1756-4646 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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